Template:BGDB Sexual Differentiation - Sex Determination Interactive: Difference between revisions

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Here are a few simple Quiz questions that relate to Sex Determination from the lecture and practical.
Here are a few simple Quiz questions that relate to Sex Determination from the lecture and practical.


++Questions to be updated++


<quiz display=simple>
<quiz display=simple>


{Which of the following is the most correct statement about the primitive streak:
{Sex determination occurs initially through the SRY transcription factor acting on the:
|type="()"}
|type="()"}
- &nbsp; extends from the primitive node to the parachordal plate
- &nbsp; primordial germ cells
- &nbsp; is a primary inducer during organogenesis
|| Incorrect! The {{primordial germ cell}}s are not involved in this initial sex determination step. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.
+ &nbsp; is a site of migration of epiblast cells to form the mesoderm
- &nbsp; anterior pituitary
|| The primitive streak is a site of migration of epiblast cells to form firstly endoderm and then the mesoderm.
|| Incorrect! The anterior pituitary participates in later hormonal events. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.
- &nbsp; persists as the parachordal plate
+ &nbsp; testes support cells
- &nbsp; all of the above are correct
|| Correct! The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into {{Sertoli cell}}s, also called sustentacular cells of Sertoli. The primordial germ cells are not involved in this initial sex determination step. The anterior pituitary participates in later hormonal events. Ovary support cells (granulosa cells) differentiate in the absence of SRY. Mesonephric duct cells, while present early in genital ridge development, are not the initiators of this process but later effected by gonad differentiation.
- &nbsp; ovary support cells
|| Incorrect! Female ovary support cells ({{granulosa cell}}s) differentiate in the absence of SRY. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.
- &nbsp; mesonephric duct cells
|| Incorrect! Mesonephric duct cells, while present early in genital ridge development, are not the initiators of this process but later effected by gonad differentiation. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.


{The cells in the adult male and female gonad forming from equivalent primordial cells in each sex are:
|type="()"}
- &nbsp; Sertoli cells and thecal cells
|| Incorrect!
- &nbsp; Leydig cells and interstitial cells
|| Incorrect!
- &nbsp; primordial germ cells and oocytes
|| Incorrect!
+ &nbsp; thecal cells and interstitial cells
|| Correct! '''Thecal cells''' (female) and  '''interstitial cells''' (male) both form the sex hormone secreting cell population in the gonads. Leydig cells and interstitial cells are 2 names for the same cell in the testis. Primordial germ cells exist in both sexes and do form oocytes, but this is not what the question asked. The ductus deferens is the male internal genital tract formed from the mesonephric ducts.
- &nbsp; ductus deferens and mesonephric ducts
|| Incorrect!
{The genes for testes-determining factors are located on the:
|type="()"}
+ &nbsp; short arm of the Y chromosome
|| Correct! The gene for testes-determining factor {{SRY}} is located on the short arm of the {{ChrY}} chromosome
- &nbsp; long arm of the Y chromosome.
|| Incorrect! {{SRY}} (sex-determining region on the Y chromosome) gene was found in 1990 on the Y and the first {{SOX}} gene identified, the sry gene encodes a "testis-determining factor" a 204aa protein (Mr 23884 Da).
|| Incorrect! The genes for testes-determining factors are located on the short arm of the {{ChrY}} chromosome. {{SRY}} (sex-determining region on the Y chromosome) gene was found in 1990 on the Y and the first {{SOX}} gene identified, the sry gene encodes a "testis-determining factor" a 204aa protein (Mr 23884 Da).
- &nbsp; short arm of the X chromosome
|| Incorrect! The genes for testes-determining factors are located on the short arm of the {{ChrY}} chromosome. {{SRY}} (sex-determining region on the Y chromosome) gene was found in 1990 on the Y and the first {{SOX}} gene identified, the sry gene encodes a "testis-determining factor" a 204aa protein (Mr 23884 Da).
- &nbsp; long arm of the X chromosome
|| Incorrect! The genes for testes-determining factors are located on the short arm of the {{ChrY}} chromosome. {{SRY}} (sex-determining region on the Y chromosome) gene was found in 1990 on the Y and the first {{SOX}} gene identified, the sry gene encodes a "testis-determining factor" a 204aa protein (Mr 23884 Da).
- &nbsp; both the X and Y chromosomes contain these genes
|| Incorrect! The genes for testes-determining factors are located on the short arm of the {{ChrY}} chromosome. {{SRY}} (sex-determining region on the Y chromosome) gene was found in 1990 on the Y and the first {{SOX}} gene identified, the sry gene encodes a "testis-determining factor" a 204aa protein (Mr 23884 Da).
{The protein product of the gene SRY acts as a
|type="()"}
- &nbsp; growth factor
|| Incorrect! Sry acts as a transcriptional activator (HMG type-high mobility group) binding to DNA and initiating male sex determination then regulating male development.
- &nbsp; endocrine factor
|| Incorrect! Sry acts as a transcriptional activator (HMG type-high mobility group) binding to DNA and initiating male sex determination then regulating male development.
- &nbsp; receptor protein
|| Incorrect! Sry acts as a transcriptional activator (HMG type-high mobility group) binding to DNA and initiating male sex determination then regulating male development.
+ &nbsp; transcription factor
|| Correct! Sry acts as a transcriptional activator (HMG type-high mobility group) binding to DNA and initiating male sex determination then regulating male development.


</quiz>
</quiz>
<br>
<br>
{{BGDALabPlacenta}}
{{BGDB SexDiffn}}
<br>
{|
{|
|-bgcolor="FAF5FF"
|-bgcolor="FAF5FF"
|  
|  
:[[Template:Med Prac additional Information|'''Additional Information:''']]  
:[[Template:Med Prac additional Information|'''Additional Information:''']] {{SRY}} | {{testis}} | {{Sertoli cell}}
|}
|}
|}<noinclude>[[Category:BGD]][[Category:Template]][[Category:Quiz]][[Category:Genital]][[Category:Male]][[Category:Female]]</noinclude>
|}<noinclude>[[Category:BGD]][[Category:Template]][[Category:Quiz]][[Category:Genital]][[Category:Male]][[Category:Female]]</noinclude>

Latest revision as of 14:19, 12 June 2019

Sex Determination Interactive Component

Attempt the Quiz - Sex Determination  
BGDsmall.jpg

Here are a few simple Quiz questions that relate to Sex Determination from the lecture and practical.


1 Sex determination occurs initially through the SRY transcription factor acting on the:

  primordial germ cells
  anterior pituitary
  testes support cells
  ovary support cells
  mesonephric duct cells

2 The cells in the adult male and female gonad forming from equivalent primordial cells in each sex are:

  Sertoli cells and thecal cells
  Leydig cells and interstitial cells
  primordial germ cells and oocytes
  thecal cells and interstitial cells
  ductus deferens and mesonephric ducts

3 The genes for testes-determining factors are located on the:

  short arm of the Y chromosome
  long arm of the Y chromosome.
  short arm of the X chromosome
  long arm of the X chromosome
  both the X and Y chromosomes contain these genes

4 The protein product of the gene SRY acts as a

  growth factor
  endocrine factor
  receptor protein
  transcription factor


BGDsmall.jpg
Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio


Additional Information: SRY | testis | sertoli cell