Template:BGDB Sexual Differentiation - Sex Determination Interactive: Difference between revisions

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-   primordial germ cells
-   primordial germ cells
|| Incorrect! The primordial germ cells are not involved in this initial sex determination step.
|| Incorrect! The primordial germ cells are not involved in this initial sex determination step. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.
-   anterior pituitary
-   anterior pituitary
|| Incorrect! The anterior pituitary participates in later hormonal events.  
|| Incorrect! The anterior pituitary participates in later hormonal events. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.
+   testes support cells
+   testes support cells
|| Correct! The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into {{Sertoli cell}}s, also called sustentacular (structural support) cells of Sertoli. The primordial germ cells are not involved in this initial sex determination step. The anterior pituitary participates in later hormonal events. Ovary support cells (granulosa cells) differentiate in the absence of SRY. Mesonephric duct cells, while present early in genital ridge development, are not the initiators of this process but later effected by gonad differentiation.
|| Correct! The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into {{Sertoli cell}}s, also called sustentacular cells of Sertoli. The primordial germ cells are not involved in this initial sex determination step. The anterior pituitary participates in later hormonal events. Ovary support cells (granulosa cells) differentiate in the absence of SRY. Mesonephric duct cells, while present early in genital ridge development, are not the initiators of this process but later effected by gonad differentiation.
-   ovary support cells
-   ovary support cells
|| Incorrect! Female ovary support cells ({{granulosa cell}}s) differentiate in the absence of SRY.
|| Incorrect! Female ovary support cells ({{granulosa cell}}s) differentiate in the absence of SRY. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.
-   mesonephric duct cells
-   mesonephric duct cells
|| Incorrect! Mesonephric duct cells, while present early in genital ridge development, are not the initiators of this process but later effected by gonad differentiation.
|| Incorrect! Mesonephric duct cells, while present early in genital ridge development, are not the initiators of this process but later effected by gonad differentiation. The support cells in the genital ridge, forming the testes, express {{SRY}} and this leads to a cascade of signaling differentiating these cells into '''{{Sertoli cell}}s''', also called sustentacular cells of Sertoli.


</quiz>
</quiz>

Revision as of 09:40, 18 May 2019

Sex Determination Interactive Component

Attempt the Quiz - Sex Determination  
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Here are a few simple Quiz questions that relate to Sex Determination from the lecture and practical.

++Questions to be updated++

Sex determination occurs initially through the SRY transcription factor acting on the:

  primordial germ cells
  anterior pituitary
  testes support cells
  ovary support cells
  mesonephric duct cells


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Practical 14: Implantation and Early Placentation | Villi Development | Maternal Decidua | Cord Development | Placental Functions | Diagnostic Techniques | Abnormalities

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