Talk:Third Trimester

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On this website the Discussion Tab or "talk pages" for a topic has been used for several purposes: References - recent and historic that relates to the topic Additional topic information - currently prepared in draft format Links - to related webpages Topic page - an edit history as used on other Wiki sites Lecture/Practical - student feedback Student Projects - online project discussions. Links: Pubmed Most Recent | Reference Tutorial | Journal Searches Glossary Links Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link Cite this page: Hill, M.A. (2024, April 16) Embryology Third Trimester. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Third_Trimester

2012

Impact of maternal characteristics on fetal growth in the third trimester of pregnancy. A population-based study

Ultrasound Obstet Gynecol. 2012 Feb 3. doi: 10.1002/uog.11125. [Epub ahead of print]

Lindell G, Maršál K, Källén K. Source Department of Obstetrics and Gynecology, Clinical Sciences Lund, Lund University, Lund, Sweden. gun.lindell@med.lu.se.

Abstract

Objectives. To investigate the association between maternal characteristics and fetal growth during the third trimester of pregnancy. Methods. Using a population-based perinatal register, 48,809 term singleton pregnancies were identified for which a routine ultrasound examination in the third trimester was performed between 1995 and 2009. Fetal and infant weight, respectively, were expressed as gestational age specific standard deviation scores (z-scores) using a Swedish ultrasound-based reference curve. The growth of each fetus was assessed using the difference between the birth weight z-score and the fetal weight z-score estimated at the ultrasound examination, adjusted for gestational age, and divided by the time elapsed between the ultrasound examination and birth. Analyses were performed using multivariate linear and polynomial regression analyses. Results. Positive associations were found between maternal body mass index (BMI), height, preexisting diabetes mellitus, and a high fetal growth, whereas maternal smoking had a negative impact. In the univariate analyses, primiparity and grand multiparity (≥4 previous children) were significantly associated with a reduced fetal growth, but in the multivariate analysis, no association between parity and fetal growth could be detected. Both the univariate and the multivariate analyses revealed a significant inverse u-shaped association between maternal age and fetal growth. Conclusions. Fetal third trimester growth was positively associated with increasing maternal BMI, height, and pre-existing diabetes mellitus, and was negatively associated with maternal smoking. No significant association between fetal growth and maternal parity or gestational diabetes mellitus was detected when adjustments were made for gestational age and the other maternal characteristics. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.

PMID 22302307

Third-trimester pregnancy complications

Prim Care. 2012 Mar;39(1):95-113.

Newfield E. Source Department of Obstetrics and Gynecology, Contra Costa Regional Medical Center, 2500 Alhambra Avenue, Martinez, CA 94543, USA. dr.emily.newfield@gmail.com

Abstract

Complications arising in the third trimester often challenge the clinician to balance the concern for maternal well-being with the consequences of infant prematurity. The most serious and challenging antepartum issues relate to preterm labor and birth, hypertensive disorders, and bleeding events. This article guides the practitioner through decision-making and management of these problems. Copyright © 2012 Elsevier Inc. All rights reserved.

PMID 22309584

http://www.primarycare.theclinics.com/article/S0095-4543(11)00092-3/abstract

A morphometric study of suprarenal gland development in the fetal period

Surg Radiol Anat. 2012 Mar 20. [Epub ahead of print]

Ozgüner G, Sulak O, Koyuncu E. Source Department of Anatomy, Faculty of Medicine, Suleyman Demirel University, 32260, Isparta, Turkey, ozgunerg@hotmail.com.

Abstract

PURPOSE: The present study's purpose was to examine the morphometric development of the suprarenal gland using anatomic dissection methods during the fetal period. METHODS: This study was performed on 172 human fetuses (76 males and 96 females) and 344 fetal suprarenal glands obtained from ages 9-40 weeks of gestation with no external pathology or anomaly. Fetuses were divided into 4 groups between gestational ages as follows: Group 1, 9-12 weeks (first trimester); Group 2, 13-25 weeks (second trimester); Group 3, 26-37 weeks (third trimester); and Group 4, 38-40 weeks (full term). Also, the fetuses were grouped into monthly cohorts: 9-12 weeks 3rd month, 13-16 weeks 4th month, 17-20 weeks 5th month, 21-24 weeks 6th month, 25-28 weeks 7th month, 29-32 weeks 8th month, 33-36 weeks 9th month, and 37-40 weeks 10th month. The suprarenal glands were dissected in the abdominal cavity. The dimensions (width, length, and thickness), volumes and weights of the suprarenal glands were evaluated. The ratio of the fetal suprarenal gland weight/fetal body weight, the ratio of the fetal suprarenal gland volume/fetal kidney volume, and the ratio of the fetal suprarenal gland dimensions/fetal kidney dimensions were evaluated. RESULTS: Mean values and standard deviations of all parameters according to gestational weeks and trimesters were calculated. It is found that all parameters increase with gestational age. There was significant correlation between gestational age and all parameters (p < 0.001). No significant differences were observed between sexes for any of the parameters (p > 0.05). There was no difference between the right and left sides of parameters except the thickness of the suprarenal glands. The left suprarenal glands were thicker than the right. The ratio of suprarenal volumes to kidney volumes was determined, and we observed that the ratio decreased during the fetal period. CONCLUSIONS: We believe that the results obtained from this study will be beneficial in understanding the development of suprarenal glands and also contribute to future studies in obstetrics, perinatology, and fetopathology.

PMID 22430763

Acute and Long-Term Purkinje Cell Loss Following a Single Ethanol Binge During the Early Third Trimester Equivalent in the Rat

Alcohol Clin Exp Res. 2012 Mar 8. doi: 10.1111/j.1530-0277.2012.01743.x. [Epub ahead of print]

Idrus NM, Napper RM. Source Department of Anatomy and Structural Biology, University of Otago, Dunedin, New Zealand. Abstract BACKGROUND: In the rat, binge-like ethanol (EtOH) exposure during the early neonatal period (a developmental period equivalent to the human third trimester) can result in a permanent deficit of cerebellar Purkinje cells (Pcells). However, the consequences of a moderate binge alcohol exposure on a single day during this postnatal period have not been established. This is an issue of importance as many pregnant women binge drink periodically at social drinking levels. This study aimed to identify both the acute and long-term effects of exposure to a single alcohol binge that achieved a mean peak blood EtOH concentration of approximately 250 mg/dl during early postnatal life using a rat model of fetal alcohol spectrum disorders. METHODS: Acute apoptotic Pcell death 10 hours after a moderate dose binge EtOH exposure from postnatal days (PDs) 0 to 10 was assessed using active caspase-3 immunolabeling. Acute Pcell apoptosis was quantified in cerebellar vermal lobules I-X using the physical disector method. Long-term effects were assessed at PD 60 using stereological methods to determine total Pcell numbers in the vermis, lobule III, and lobule IX, following a moderate dose binge EtOH exposure at PDs 0, 2, or 4. RESULTS: Acute apoptosis was induced by EtOH on PDs 1 to 8 in a time and lobular-dependent manner. For EtOH exposure on PD 2, significant long-term Pcell loss occurred in lobule III. EtOH exposure on PD 4 resulted in significant long-term Pcell loss throughout the entire vermis. CONCLUSIONS: These results indicate that a single, early EtOH episode of moderate dose can create significant and permanent Pcell loss in the developing cerebellum. Copyright © 2012 by the Research Society on Alcoholism.

PMID 22404759

2006

Teenage pregnancy: use of drugs in the third trimester and prevalence of psychiatric disorders

Rev Bras Psiquiatr. 2006 Jun;28(2):122-5. Epub 2006 Jun 26.

Mitsuhiro SS, Chalem E, Barros MM, Guinsburg R, Laranjeira R. Source Research Unit of Alcohol and Drugs, Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, SP, Brazil. mitsuhiro@uol.com.br

Abstract

OBJECTIVE: To determine the prevalence of psychiatric disorders during pregnancy, the prevalence of cocaine and marijuana use during the third trimester of gestation and the socio-demographic characteristics of a population of low-income teenagers. METHOD: One thousand pregnant teenagers were evaluated using the Composite International Diagnostic Interview, and a socio-demographic and socio-economic questionnaire at the obstetric center of a public hospital in São Paulo, Brazil. Hair sample was collected for analysis. RESULTS: Of the 1000 pregnant teenagers interviewed, 53.6% were poor, 90.4% were unemployed, 92.5% were financially dependent and 60.2% dropped out of school. Those using drugs during the third trimester of pregnancy were equal to 6% (marijuana: 4%, cocaine: 1.7%, both: 0.3%). Those having at least one psychiatric disorder equaled 27.6%. The most frequent diagnoses were depression (12.9%), posttraumatic stress disorder (10.0%) and anxiety disorders (5.6%). DISCUSSION: Unstructured families, dropping out of school, unemployment and a low level of professional training are all contributing factors to the maintenance of an unfavorable socio-economic environment in which there is a high prevalence of cocaine and marijuana use during the third trimester of pregnancy and an abnormally high incidence of psychiatric disorders.

PMID 16810395

2005

Third-trimester ultrasound dating algorithms derived from pregnancies conceived with artificial reproductive techniques

Ultrasound Obstet Gynecol. 2005 Aug;26(2):129-31.

Mongelli M, Chew S, Yuxin NG, Biswas A. Source Division of Women and Children's Health, Nepean Hospital, Penrith, NSW, Australia. max_mongelli@yahoo.com

Abstract

OBJECTIVE: To derive an accurate formula for ultrasound estimation of gestational age in late pregnancy. METHODS: A database of 123 singleton pregnancies conceived by artificial reproductive techniques with third-trimester ultrasound measurements was studied. Biometry variables included the fetal head circumference (HC) and femur length (FL). The dataset was equally divided into a derivation sample and a target sample. To derive the equations of best fit, regression analysis was used, with true menstrual age as the dependent variable and fetal biometry measurements as independent variables. The formulae were tested on the target set and the menstrual age estimates were compared with the actual menstrual age. Clinical performance was estimated in terms of systematic and random errors, absolute errors and their 95% CI values. RESULTS: The menstrual ages at time of scanning ranged from 26 to 41 weeks, with a mean of 33 weeks. The best performing derived formula was a combination of HC and FL. This had a random error of 7.5 days and prediction errors within a 95% confidence limit of -13 to +17 days. With FL only, the random error was 8.2 days, whereas using the HC only yielded a random error of 9.4 days. CONCLUSIONS: Ultrasound estimation of gestational age in late pregnancy is better than indicated by older publications. It is more accurately estimated by combining the HC with the FL than by using the FL measurements alone. Copyright 2005 ISUOG. Published by John Wiley & Sons, Ltd.

PMID 16041677