Talk:Renal System - Abnormalities: Difference between revisions
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==2010== | |||
===Bilateral intravesical ureterocele associated with unilateral partial duplication of the ureter and other anomalies: proposal of a new variant to the classification of ureterocles based on a perinatal autopsy, review of the literature and embryology=== | ===Bilateral intravesical ureterocele associated with unilateral partial duplication of the ureter and other anomalies: proposal of a new variant to the classification of ureterocles based on a perinatal autopsy, review of the literature and embryology=== | ||
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PMID: 20854476 | PMID: 20854476 | ||
==2009== | |||
===Increased prevalence of renal and urinary tract anomalies in children with Down syndrome=== | |||
Pediatrics. 2009 Oct;124(4):e615-21. Epub 2009 Sep 14. | |||
Kupferman JC, Druschel CM, Kupchik GS. | |||
Source | |||
Divisions of Pediatric Nephrology and Hypertension, Maimonides Infants and Children's Hospital, Brooklyn, New York 11219, USA. jkupferman@maimonidesmed.org | |||
Abstract | |||
OBJECTIVE: | |||
The goal was to investigate the prevalence of renal and urinary tract anomalies (RUTAs) in a Down syndrome (DS) population. | |||
METHODS: | |||
Data were obtained from the New York State Congenital Malformation Registry (NYS-CMR) in this retrospective cohort study. The occurrence of RUTAs was assessed for children with and without DS who were born in NYS between 1992 and 2004. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for each malformation. | |||
RESULTS: | |||
Between 1992 and 2004, 3832 children with DS and 3 411 833 without DS were born in NYS. The prevalence of RUTAs in the DS population was 3.2%, compared with 0.7% in the NYS population (OR: 4.5 [95% CI: 3.8 -5.4]). Children with DS had significantly increased risks of anterior urethral obstruction (OR: 29.7 [95% CI: 4.0 -217.7]), cystic dysplastic kidney (OR: 4.5 [95% CI: 1.5-14.1]), hydronephrosis (OR: 8.7 [95% CI: 6.8 -11.0]), hydroureter (OR: 8.5 [95% CI: 3.5-20.4]), hypospadias (OR: 2.0 [95% CI: 1.4 -2.9]), posterior urethral valves (OR: 7.1 [95% CI: 1.8 -28.8]), prune belly syndrome (OR: 11.9 [95% CI: 1.6 - 85.4]), and renal agenesis (OR: 5.4 [95% CI: 2.8 -10.4]). There was no significantly increased risk of ectopic kidney (OR: 1.6 [95% CI: 0.2-11.2]) or ureteropelvic junction obstruction (OR: 1.4 [95% CI: 0.2-9.9]) in the DS population. | |||
CONCLUSION: | |||
Children with DS have significantly increased risks of RUTAs. | |||
PMID: 19752083 | |||
http://www.ncbi.nlm.nih.gov/pubmed/19752083 | |||
==2006== | |||
===Congenital Megacalyces=== | ===Congenital Megacalyces=== | ||
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his 10-month old male had a large left kidney, thought to be due to tumour. A CT of the renal tracts was performed, which shows no tumour, but confirms enlargement of the left kidney. The image shown is a posterior view from a 3D reconstruction of the excretory phase of the examination (click image for frontal MIP, a virtual IVP). There are more than the usual number of calyces, and they have a bizarre polygonal, faceted shape. | his 10-month old male had a large left kidney, thought to be due to tumour. A CT of the renal tracts was performed, which shows no tumour, but confirms enlargement of the left kidney. The image shown is a posterior view from a 3D reconstruction of the excretory phase of the examination (click image for frontal MIP, a virtual IVP). There are more than the usual number of calyces, and they have a bizarre polygonal, faceted shape. | ||
Congenital megacalyces are thought to be due to developmental hypoplasia of the medullary pyramids. The enlarged, floppy calyces predispose to statis, infection and calculus formation. There is an association with congenital megaureter. | Congenital megacalyces are thought to be due to developmental hypoplasia of the medullary pyramids. The enlarged, floppy calyces predispose to statis, infection and calculus formation. There is an association with congenital megaureter. | ||
Revision as of 15:14, 27 April 2011
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Cite this page: Hill, M.A. (2024, April 19) Embryology Renal System - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Renal_System_-_Abnormalities |
2010
Bilateral intravesical ureterocele associated with unilateral partial duplication of the ureter and other anomalies: proposal of a new variant to the classification of ureterocles based on a perinatal autopsy, review of the literature and embryology
APMIS. 2010 Oct;118(10):809-14. doi: 10.1111/j.1600-0463.2010.02666.x. Epub 2010 Aug 17.
Jaiman S, Ulhøj BP. Department of Pathology, Randers Regional Hospital, Randers NØ, Denmark. sunijaim@rm.dk Abstract The aims of this study were to demonstrate a case of bilateral intravesical ureterocele associated with megacystis and mega-ureters, unilateral partial duplication of the ureter and unilateral segmental renal dysplasia of the upper pole and an accessory spleen and to propose an addition of the new variant to the classification of ureteroceles. A perinatal necropsy was conducted on the 21-week fetus by employing the Rokitansky procedure with evisceration performed in blocks. The autopsy revealed the aforementioned abnormalities without cardiac or neural anomalies. The amniocentesis report was normal. Ureterocele is a saccular expansion of the distal ureter. It is most commonly observed in females and children and usually affects the upper moiety of a complete pyeloureteral duplication. Four types of ureteroceles are described: (A) ureterocele with single ureter (10%); (B) ureterocele with total duplication and intravesical development (10%); (C) ureterocele with total duplication and extravesical development (62%); and (D) ureterocele with ectopic ureter (3%). One case in a new born with bilateral intravesical ureterocele associated with hydrouretero-nephrosis and hyperechogenic spots in kidneys has been reported, but bilateral intravesical ureterocele with unilateral incomplete pyeloureteral duplication has never been described in the literature. © 2010 The Authors. Journal Compilation © 2010 APMIS.
PMID: 20854476
2009
Increased prevalence of renal and urinary tract anomalies in children with Down syndrome
Pediatrics. 2009 Oct;124(4):e615-21. Epub 2009 Sep 14.
Kupferman JC, Druschel CM, Kupchik GS. Source Divisions of Pediatric Nephrology and Hypertension, Maimonides Infants and Children's Hospital, Brooklyn, New York 11219, USA. jkupferman@maimonidesmed.org Abstract OBJECTIVE: The goal was to investigate the prevalence of renal and urinary tract anomalies (RUTAs) in a Down syndrome (DS) population.
METHODS: Data were obtained from the New York State Congenital Malformation Registry (NYS-CMR) in this retrospective cohort study. The occurrence of RUTAs was assessed for children with and without DS who were born in NYS between 1992 and 2004. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for each malformation.
RESULTS: Between 1992 and 2004, 3832 children with DS and 3 411 833 without DS were born in NYS. The prevalence of RUTAs in the DS population was 3.2%, compared with 0.7% in the NYS population (OR: 4.5 [95% CI: 3.8 -5.4]). Children with DS had significantly increased risks of anterior urethral obstruction (OR: 29.7 [95% CI: 4.0 -217.7]), cystic dysplastic kidney (OR: 4.5 [95% CI: 1.5-14.1]), hydronephrosis (OR: 8.7 [95% CI: 6.8 -11.0]), hydroureter (OR: 8.5 [95% CI: 3.5-20.4]), hypospadias (OR: 2.0 [95% CI: 1.4 -2.9]), posterior urethral valves (OR: 7.1 [95% CI: 1.8 -28.8]), prune belly syndrome (OR: 11.9 [95% CI: 1.6 - 85.4]), and renal agenesis (OR: 5.4 [95% CI: 2.8 -10.4]). There was no significantly increased risk of ectopic kidney (OR: 1.6 [95% CI: 0.2-11.2]) or ureteropelvic junction obstruction (OR: 1.4 [95% CI: 0.2-9.9]) in the DS population.
CONCLUSION: Children with DS have significantly increased risks of RUTAs.
PMID: 19752083 http://www.ncbi.nlm.nih.gov/pubmed/19752083
2006
Congenital Megacalyces
http://www.radpod.org/2006/12/27/congenital-megacalyces/
his 10-month old male had a large left kidney, thought to be due to tumour. A CT of the renal tracts was performed, which shows no tumour, but confirms enlargement of the left kidney. The image shown is a posterior view from a 3D reconstruction of the excretory phase of the examination (click image for frontal MIP, a virtual IVP). There are more than the usual number of calyces, and they have a bizarre polygonal, faceted shape. Congenital megacalyces are thought to be due to developmental hypoplasia of the medullary pyramids. The enlarged, floppy calyces predispose to statis, infection and calculus formation. There is an association with congenital megaureter.
- Renal ectopy
- Renal fusion
- asymptomatic renal ectopia
