Talk:Mouse Estrous Cycle

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Cite this page: Hill, M.A. (2024, March 28) Embryology Mouse Estrous Cycle. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Mouse_Estrous_Cycle

http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0000382

Naturally occurring Foxp3+regulatory T cells play an important role in the inhibition of an immunological attack of the fetus. As implantation of the fetus poses an immediate antigenic challenge, the immune system has to prepare itself for this event prior to implantation.

2015

Vaginal Cytology of the Laboratory Rat and Mouse: Review and Criteria for the Staging of the Estrous Cycle Using Stained Vaginal Smears

Toxicol Pathol. 2015 Mar 3. pii: 0192623315570339.

Cora MC1, Kooistra L2, Travlos G3.

Abstract

Microscopic evaluation of the types of cells present in vaginal smears has long been used to document the stages of the estrous cycle in laboratory rats and mice and as an index of the functional status of the hypothalamic-pituitary-ovarian axis. The estrous cycle is generally divided into the four stages of proestrus, estrus, metestrus, and diestrus. On cytological evaluation, these stages are defined by the absence, presence, or proportion of 4 basic cell types as well as by the cell density and arrangement of the cells on the slide. Multiple references regarding the cytology of the rat and mouse estrous cycle are available. Many contemporary references and studies, however, have relatively abbreviated definitions of the stages, are in reference to direct wet mount preparations, or lack comprehensive illustrations. This has led to ambiguity and, in some cases, a loss of appreciation for the encountered nuances of dividing a steadily moving cycle into 4 stages. The aim of this review is to provide a detailed description, discussion, and illustration of vaginal cytology of the rat and mouse estrous cycle as it appears on smears stained with metachromatic stains. © 2015 by The Author(s). KEYWORDS: diestrus; estrus; metestrus.; proestrus

PMID 25739587