Difference between revisions of "Talk:K12 Limbs"

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{|
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|-bgcolor="CEDFF2"
| width=200px|Axis
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! width=150px|Axis
| Proximodistal  
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! width=210px|Proximodistal  
| Dorsoventral  
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! width=210px|Dorsoventral  
| Anteroposterior
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! width=210px|Anteroposterior
 
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| Limb Structure
 
| Limb Structure
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| back and front of the limb
 
| back and front of the limb
 
| order of digits
 
| order of digits
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|-bgcolor="F5FAFF"
 
| Gene
 
| Gene
 
| Wnt7a growth factor then secretes other growth factors (FGF2, 4, 8)
 
| Wnt7a growth factor then secretes other growth factors (FGF2, 4, 8)
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| Where
 
| Where
| at tip of the limb Apical Ectodermal Ridge (AER)
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| tip of the limb Apical Ectodermal Ridge (AER)
 
| back of the limb
 
| back of the limb
 
| mesenchyme Zone of Polarizing Activity (ZPA)
 
| mesenchyme Zone of Polarizing Activity (ZPA)
 
|-
 
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| Expression Example (mouse)
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| Expression Example<br>(mouse)
 
| [[File:Limb patterning factors 04.jpg|200px]]
 
| [[File:Limb patterning factors 04.jpg|200px]]
 
| [[File:Limb patterning factors 01.jpg|200px]]
 
| [[File:Limb patterning factors 01.jpg|200px]]
 
| [[File:Limb patterning factors 03.jpg|200px]]
 
| [[File:Limb patterning factors 03.jpg|200px]]
 
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Latest revision as of 15:54, 12 September 2016

9 The timing of gene expression is important in the developmental process

9.1 Identify the role of genes in embryonic development

9.2 Summarise the role of gene cascades in determining limb formation in birds and mammals.

9.3 Describe the evidence which indicates the presence of ancestral vertebrate gene homologues in lower animal classes

9.4 Discuss the evidence available from current research about the evolution of genes and their actions

9.5 Identify data sources, gather, process and analyse information from secondary sources and use available evidence to assess the evidence that analysis of genes provides for evolutionary relationships


Axis Proximodistal Dorsoventral Anteroposterior
Limb Structure shoulder to fingers, hip to toes back and front of the limb order of digits
Gene Wnt7a growth factor then secretes other growth factors (FGF2, 4, 8) Wnt7a growth factor Sonic hedgehog (SHH)
Where tip of the limb Apical Ectodermal Ridge (AER) back of the limb mesenchyme Zone of Polarizing Activity (ZPA)
Expression Example
(mouse)
Limb patterning factors 04.jpg Limb patterning factors 01.jpg Limb patterning factors 03.jpg