Talk:Historic Animation - Heart 04
Part 1 Summary
Introduction to early development
Heart layers - epicardium, myocardium, endocardium
Week 3 Heart Fields Epicardiomantle Mesenchymal cells Endocardium development from double to single tube Cephalic end connects with dorsal aortas Caudal end connects with vitelline veins
End Week 3 Single thin-walled tube Tube bengins to bend
Part 2 Summary
Scale Bar 1 mm
Sinus venosus - draining fluid and blood cells from 3 pairs of vessels (vitelline veins, umbilical veins, common cardinal veins) common cardinal veins = ducts of Cuvier
Heart tube - bends ventrally to the right
Primitive atria - above sinus venosus
Conus - above primitive atria
Truncus arteriosus - above conus
Aortic arches - above truncus arteriosus
Caudal to cranial sequence sinus venosus - primitive atria - conus - truncus arteriosus - aortic arches
Middle Week 3
Splanchnopleuric mesoderm - differentiated into epimyocardial mantle around the tubes
Two heart tubes - brought together by the folding of the body
Foregut - lies dorsal to the heart tubes
End Week 3
Spontaneous cardiac contractions
Detachment of the heart tube dorsally
Primordia of transverse sinus of the pericardium
Part 3 Summary
Four separate shifts of position
Week 4
- Shift 1 - Head fold growth rotates heart and cavity 180 degrees
- Shift 2 - Curvature of the body, cephalic growth
Week 5
- Shift 3 and 4 - Growth of the liver
Week 4 - First aortic arches declining, Third arches well developed
- Myogenic contractions sufficient to circulate blood
- Atrium migrates to higher location
Week 5 - Ventricles do not contract simultaneously
Week 6 - Separation of outflow has begun
Part 4 Summary
Week 7 - (outflow) aortic and pulmonary trunks completely separated
Week 8 - external form similar to that at birth
0.5 mm to 5 mm growth
Week 4 - Dorsal view, Sinus venosus migrates towards the right
End of week 4 forth arches appear
sinus venosus single opening into atria
Week 5 - branched pulmonary vein arises
hepatic part of inferior vena cava (IVC) developing within liver
right pulmonary arch declining to disappear
Week 6 - pulmonary branches taken up by left atrium
Week 7 and 8 - superior vena cava (SVC) migrates upwards
End of Week 8 - coronary sinus, draining veins of cardiac wall
Week 11 - 4 secondary pulmonary branches have openings into the left atrium
