Talk:Gastrointestinal Tract - Stomach Development

From Embryology

Gastrointestinal Tract - Stomach

Introduction

This section of notes gives an overview of how the stomach and duodenum develops. The GIT is best imagined as a simple tube, the upper part being the foregut diverticulum, which is further divided into oesophagus and stomach.


File:D5lst13stom.gif
File:Stomach.jpg
Embryo stage 13/14 stomach
Adult stomach anatomy

During week 4 where the stomach will form the tube begins to dilate, forming an enlarged lumen in the tube. Dorsal border grows more rapidly than ventral, which establishes the greater curvature of the stomach. A second rotation (of 90 degrees) occurs on the longitudinal axis establishing the adult orientation of the stomach.

Stage 13/14 Stomach

File:St1314sm.gif File:D2st13stom.gif File:D3lst13stom.gif File:D4st13stom.gif
Sections from D2 to D7 downward.
(viewed from beneath, top is right, bottom is left)
View through osophageal pyloric region at top of stomach.(base of R. and L. lung buds) Beginning of stomach rotation. Broad dorsal mesogastrium, narrow ventral mesogastrium. Cavity beneath stomach is the omentum bursa. Section through the body of the stomach. Dorsal mesogastrium beneath the omentum bursa will form greater omentum.
File:D5st13stom.gif File:D6st13stom.gif File:D7st13stom.gif
Section through the body of the stomach. Section at the stomach duodenal junction.

Stage 22 Stomach

File:St22hum.gif File:E6lst22stom.gif File:E7lst22stom.gif
Sections from E6 to D4 downward.
Note thick muscular wall of stomach body and change in lumen shape between pyloris and duodenum.
File:F1lst22stom.gif File:F2lst22stom.gif File:F3lst22stom.gif
File:F4lst22stom.gif File:F5lst22stom.gif
File:Mov.gifSee[../Movies/st22/e6f5lstom.mov Labelled Movie of Stomach][../Movies/st22/e6f5lstom.mov ][../Movies/st22/e6f5lstom.mov (sections E6-D5)](237 Kb)
[../embryo/Movies/st22/e6f5stom.mov Unlabelled Movie](243 Kb)

Greater Omentum

The greater omentum hangs like an apron over the small intestine and transverse colon. It begins attacted to the inferior end of the stomach as a fold of the dorsal mesogastrium which later fuses to form the structure we recognise anatomically. The figure below shows a lateral view of this process comparing the early second trimester arrangement with the newborn structure. (More? [git12.htm GIT Folding])


Development of the greater omentum

Stomach Development Movies

File:Stomrot.jpg[../Movies/larsen/stomrot.mov Stomach Rotation] (326 Kb) File:Stomrot2.jpg[../Movies/larsen/stomrot2.mov Stomach Rotation ]large version (620 Kb)
File:LessersacA.jpg[../Movies/larsen/lessersacA.mov Lesser Sac ]superior view (104 Kb) File:LessersacB.jpg[../Movies/larsen/lessersacB.mov Lesser Sac] ventrolateral view (408 Kb)

3D Model Movies

The following are links to 3D reconstruction animations of serial images of the gastrointestinal tract at an early and late embryonic stage. (More? [3dmodel.htm 3D Model Movies])

File:Git resp kidney.gif

Stage 13/14 Embryo: [../Movies/GIT3dmodel.htm Gastrointestinal Tract]

Stage 22 Embryo: [../Movies/GIT3dmodelst22.htm Gastrointestinal Tract]

Adult Stomach Position


File:Stomach-position.jpg Movie of anatomical position of the erect adult stomach position on filling, based upon historic drawings.

Quicktime: [../Movies/git/adult_stomach_position.mov adult_stomach_position.mov (36 Kb)]

Abnormalities

  • Congenital hypertrophic pyloric stenosis
  • duodenal atresia
  • duodenal stenosis

WWW Links

Indiana University animation showing Development of the Stomach, Omenta and Duodenum Discussion of the development of the stomach from the foregut, the omenta development from the mesenteries, and the rotational movements of the stomach and duodenum.(approx. 2 minutes)