Talk:Developmental Mechanisms

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On this website the Discussion Tab or "talk pages" for a topic has been used for several purposes: References - recent and historic that relates to the topic Additional topic information - currently prepared in draft format Links - to related webpages Topic page - an edit history as used on other Wiki sites Lecture/Practical - student feedback Student Projects - online project discussions. Links: Pubmed Most Recent | Reference Tutorial | Journal Searches Glossary Links Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link Cite this page: Hill, M.A. (2024, April 16) Embryology Developmental Mechanisms. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Developmental_Mechanisms

http://www.nature.com/nrg/journal/v7/n4/full/nrg1830.html

2012

Cilia, calcium and the basis of left-right asymmetry

BMC Biol. 2012 Dec 19;10:102. doi: 10.1186/1741-7007-10-102.

Norris DP. Source Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. d.norris@har.mrc.ac.uk. Abstract ABSTRACT: The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body. How leftward flow is interpreted and information propagated to other tissues is the subject of debate. Four recent papers have shed fresh light on the possible mechanisms.

PMID 23256866

Extracellular matrix and cytoskeletal dynamics during branching morphogenesis

Organogenesis. 2012 Apr-Jun;8(2):56-64. doi: 10.4161/org.19813. Epub 2012 Apr 1.

Kim HY, Nelson CM. Source Department of Chemical and Biological Engineering, Princeton University; Princeton, NJ USA.

Abstract

Branching morphogenesis is a fundamental developmental process which results in amplification of epithelial surface area for exchanging molecules in organs including the lung, kidney, mammary gland and salivary gland. These complex tree-like structures are built by iterative rounds of simple routines of epithelial morphogenesis, including bud formation, extension, and bifurcation, that require constant remodeling of the extracellular matrix (ECM) and the cytoskeleton. In this review, we highlight the current understanding of the role of the ECM and cytoskeletal dynamics in branching morphogenesis across these different organs. The cellular and molecular mechanisms shared during this morphogenetic process provide insight into the development of other branching organs. PMID 22609561

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429513/

http://www.landesbioscience.com/journals/organogenesis/article/19813/?nocache=1100256833

2011

The bending of cell sheets--from folding to rolling

BMC Biol. 2011 Dec 29;9:90. Keller R, Shook D. Source Department of Biology, 241 Gilmer Hall, University of Virginia, Charlottesville, VA 22904, USA. rek3k@virginia.edu

Abstract

The bending of cell sheets plays a major role in multicellular embryonic morphogenesis. Recent advances are leading to a deeper understanding of how the biophysical properties and the force-producing behaviors of cells are regulated, and how these forces are integrated across cell sheets during bending. We review work that shows that the dynamic balance of apical versus basolateral cortical tension controls specific aspects of invagination of epithelial sheets, and recent evidence that tissue expansion by growth contributes to neural retinal invagination in a stem cell-derived, self-organizing system. Of special interest is the detailed analysis of the type B inversion in Volvox reported in BMC Biology by Höhn and Hallmann, as this is a system that promises to be particularly instructive in understanding morphogenesis of any monolayered spheroid system. © 2011 Keller and Shook; licensee BioMed Central Ltd.

PMID 22206439