Talk:Detailed Cardiac - Atrioventricular Conduction Axis
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Cite this page: Hill, M.A. (2021, March 4) Embryology Detailed Cardiac - Atrioventricular Conduction Axis. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Detailed_Cardiac_-_Atrioventricular_Conduction_Axis
Three Dimensional Visualization of Human Cardiac Conduction Tissue in Whole Heart Specimens by High-Resolution Phase-Contrast CT Imaging Using Synchrotron Radiation
World J Pediatr Congenit Heart Surg. 2016 Nov;7(6):700-705.
Shinohara G1, Morita K2, Hoshino M3, Ko Y1, Tsukube T4, Kaneko Y5, Morishita H5, Oshima Y6, Matsuhisa H6, Iwaki R6, Takahashi M7, Matsuyama T8, Hashimoto K1, Yagi N3.
BACKGROUND: The feasibility of synchrotron radiation-based phase-contrast computed tomography (PCCT) for visualization of the atrioventricular (AV) conduction axis in human whole heart specimens was tested using four postmortem structurally normal newborn hearts obtained at autopsy. METHODS: A PCCT imaging system at the beamline BL20B2 in a SPring-8 synchrotron radiation facility was used. The PCCT imaging of the conduction system was performed with "virtual" slicing of the three-dimensional reconstructed images. For histological verification, specimens were cut into planes similar to the PCCT images, then cut into 5-μm serial sections and stained with Masson's trichrome. RESULTS: In PCCT images of all four of the whole hearts of newborns, the AV conduction axis was distinguished as a low-density structure, which was serially traceable from the compact node to the penetrating bundle within the central fibrous body, and to the branching bundle into the left and right bundle branches. This was verified by histological serial sectioning. CONCLUSION: This is the first demonstration that visualization of the AV conduction axis within human whole heart specimens is feasible with PCCT. © The Author(s) 2016. KEYWORDS: atrioventricular conduction axis; cardiac anatomy/pathologic anatomy; conduction system; congenital heart disease (CHD); congenital heart surgery; imaging (all modalities); myocardial morphology
PMID 27834761 DOI: 10.1177/2150135116675844