Talk:2018 Group Project 4: Difference between revisions

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During early development neural folds are formed along the anteroposterior-axis in the ectoderm. Upon fusion the folds give rise to the neural tube. During the process of neural tube formation, cells detach at the border of the neural and epidermal ectoderm, i.e. at the dorsal aspect of the forming neural tube. These cells are referred to as neural crest cells. Neural crest cells migrate along defined pathways throughout the body. Upon arrival at their destination, they differentiate into various cell types, among which melanocytes, peripheral neurons and their supporting cells, and skeletal elements. The neural crest cells are formed along the entire cranio–caudal axis of the body and can be divided into two major populations the cranial and truncal neural crest cells. The cranial neural crest extends from the diencephalon up to somite pair 5, and the truncal neural crest from somite pair 6 to the caudal end of the neural tube. The truncal neural crest is involved in sympathetic innervation of the heart, whereas the cranial neural crest is associated with parasympathetic innervation of the heart.
"During early development neural folds are formed along the anteroposterior-axis in the ectoderm. Upon fusion the folds give rise to the neural tube. During the process of neural tube formation, cells detach at the border of the neural and epidermal ectoderm, i.e. at the dorsal aspect of the forming neural tube. These cells are referred to as neural crest cells. Neural crest cells migrate along defined pathways throughout the body. Upon arrival at their destination, they differentiate into various cell types, among which melanocytes, peripheral neurons and their supporting cells, and skeletal elements. The neural crest cells are formed along the entire cranio–caudal axis of the body and can be divided into two major populations the cranial and truncal neural crest cells. The cranial neural crest extends from the diencephalon up to somite pair 5, and the truncal neural crest from somite pair 6 to the caudal end of the neural tube. The truncal neural crest is involved in sympathetic innervation of the heart, whereas the cranial neural crest is associated with parasympathetic innervation of the heart."




{{#pmid:10946058}}
{{#pmid:10946058}}
[[User:Z5229185|Z5229185]] ([[User talk:Z5229185|talk]]) 11:51, 21 August 2018 (AEST) Sounds good for a brief introduction of the neural crest roles to the heart development


===Embryonic origins/embyronic contributions===
===Embryonic origins/embyronic contributions===

Revision as of 12:51, 21 August 2018

Projects 2018: 1 Adrenal Medulla | 3 Melanocytes | 4 Cardiac | 5 Dorsal Root Ganglion

Project Pages are currently being updated (notice removed when completed)

Neural Crest and Cardiovascular Development

About this Discussion Page

The project discussion page is where your group members can post discussion on the project topic. This will be demonstrated in the practical tutorial in week 3.

Please follow these 3 simple rules:

  1. Never identify yourself or any other students by name, use only your student number.
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  3. Only add content that is both correctly cited and you have permission to reuse.
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Mark Hill.jpg Science Student Projects
  1. The key points relating to the topic that your group allocated are clearly described.
  2. The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area.
  3. Content is correctly cited and referenced.
  4. The wiki has an element of teaching at a peer level using the student's own innovative diagrams, tables or figures and/or using interesting examples or explanations.
  5. Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities.
  6. Relates the topic and content of the Wiki entry to learning aims of embryology.
  7. Clearly reflects on editing/feedback from group peers and articulates how the Wiki could be improved (or not) based on peer comments/feedback. Demonstrates an ability to review own work when criticised in an open edited wiki format. Reflects on what was learned from the process of editing a peer's wiki.
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  9. The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning.
  10. Develops and edits the wiki entries in accordance with the above guidelines.
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Z5229189 (talk) 12:28, 14 August 2018 (AEST)

Neural Crest and Cardiac Development

Introduction/history/structure of the cardiovascular network/histology/anatomy/physiology

"During early development neural folds are formed along the anteroposterior-axis in the ectoderm. Upon fusion the folds give rise to the neural tube. During the process of neural tube formation, cells detach at the border of the neural and epidermal ectoderm, i.e. at the dorsal aspect of the forming neural tube. These cells are referred to as neural crest cells. Neural crest cells migrate along defined pathways throughout the body. Upon arrival at their destination, they differentiate into various cell types, among which melanocytes, peripheral neurons and their supporting cells, and skeletal elements. The neural crest cells are formed along the entire cranio–caudal axis of the body and can be divided into two major populations the cranial and truncal neural crest cells. The cranial neural crest extends from the diencephalon up to somite pair 5, and the truncal neural crest from somite pair 6 to the caudal end of the neural tube. The truncal neural crest is involved in sympathetic innervation of the heart, whereas the cranial neural crest is associated with parasympathetic innervation of the heart."


van den Hoff MJ & Moorman AF. (2000). Cardiac neural crest: the holy grail of cardiac abnormalities?. Cardiovasc. Res. , 47, 212-6. PMID: 10946058 Z5229185 (talk) 11:51, 21 August 2018 (AEST) Sounds good for a brief introduction of the neural crest roles to the heart development

Embryonic origins/embyronic contributions

Early development

Later development

Developmental time course/carnegie stages/overview

Cell signalling involved/molecular mechanisms/factors/genes

Disorders/abnormalities

Current research/main animal models/future questions

Reference

PMID: 10359559 Waldo K, Zdanowicz M, Burch J, Kumiski DH, Stadt HA, Godt RE, Creazzo TL & Kirby ML. (1999). A novel role for cardiac neural crest in heart development. J. Clin. Invest. , 103, 1499-507. PMID: 10359559 DOI.

<pubmed limit=5>Neural Crest Embryology</pubmed>


A novel role for cardiac neural crest in heart development

PMID: 10359559 Waldo K, Zdanowicz M, Burch J, Kumiski DH, Stadt HA, Godt RE, Creazzo TL & Kirby ML. (1999). A novel role for cardiac neural crest in heart development. J. Clin. Invest. , 103, 1499-507. PMID: 10359559 DOI.

Z5229281 (talk) 12:47, 14 August 2018 (AEST)

Z5229185 (talk) 12:48, 14 August 2018 (AEST)

Z5229177 (talk) 12:49, 14 August 2018 (AEST)

Z5229189 (talk) 12:51, 14 August 2018 (AEST)