Talk:2016 Group Project 2

Group Assessment Criteria   Science Student Projects The key points relating to the topic that your group allocated are clearly described. The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area. Content is correctly cited and referenced. The wiki has an element of teaching at a peer level using the student's own innovative diagrams, tables or figures and/or using interesting examples or explanations. Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities. Relates the topic and content of the Wiki entry to learning aims of embryology. Clearly reflects on editing/feedback from group peers and articulates how the Wiki could be improved (or not) based on peer comments/feedback. Demonstrates an ability to review own work when criticised in an open edited wiki format. Reflects on what was learned from the process of editing a peer's wiki. Evaluates own performance and that of group peers to give a rounded summary of this wiki process in terms of group effort and achievement. The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning. Develops and edits the wiki entries in accordance with the above guidelines. More Information on Assessment Criteria | Science Student Projects

Signalling: 1 Wnt | 2 Notch | 3 FGF Receptor | 4 Hedgehog | 5 T-box | 6 TGF-Beta

Here are some starting places for the topic. Can be patterning, differentiation, etc. as long as a developmental signal process/pathway.

Molecular Development - Signaling Bookshelf Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Universal Mechanisms of Animal Development. Available from: http://www.ncbi.nlm.nih.gov/books/NBK26825/ Cooper GM. The Cell: A Molecular Approach. 2nd edition. Sunderland (MA): Sinauer Associates; 2000. Signaling in Development and Differentiation. Available from: http://www.ncbi.nlm.nih.gov/books/NBK9918/ Interactive Fly - Evolutionarily conserved developmental pathways PMID 12509752 PMID 19399989

Z5015014 (talk) 14:27, 16 September 2016 (AEST) looks like a great picture so I think we can leave it. I just altered the formatting of the image a little bit, but feel free to change it back if you prefer the previous placement! also I think having the copyright info on the file page is enough. thanks for doing that, I'm still hunting out pictures as well. I've been busy this week with another group project but now that it's out of the way I should be able to do a lot more here. :)

Z3462474 (talk) 09:21, 16 September 2016 (AEST) I found one that didnt look too complicated and also found that it allowed unrestricted use so I've added it into the cardio section of our page (we can always delete it later if need be), not 100% about my formatting though and whether I should include the legend/copyright notice directly on our page? If you click the image though its all there :)

Z5015014 (talk) 23:08, 12 September 2016 (AEST) I've been looking around and found some images, but most of the time they involve a lot more detail than we need and I don't want to overcomplicate it. will keep researching this week and see if I can find some simpler diagrams. :) The images in that book look really good but yeah I'm not sure what the copyright details for that are. if it comes to it I think if we reproduce it by hand and credit the source then it's fine!

Z3462474 (talk) 13:50, 12 September 2016 (AEST) Has anyone found any good images to use for our page? I have found a couple of diagrams on cardiac development and Notch in this book chapter: http://www.sciencedirect.com.wwwproxy0.library.unsw.edu.au/science/article/pii/S0070215310920115 but am still looking to the copyright restrictions etc and thought I'd check everyone's opinion

Z3462474 (talk) 09:22, 9 September 2016 (AEST) Hey everyone, I have added some of my notes to the main page, they are still a work in progress though! I'll continue to research the roles of Notch in the development of the different systems

Z3462474 (talk) 10:04, 2 September 2016 (AEST) Just found this online textbook titled 'Notch Signaling : Methods and Protocols' http://www.springerprotocols.com.wwwproxy0.library.unsw.edu.au/BookToc/doi/10.1007/978-1-4939-1139-4

This one also looks like it might be helpful: http://www.sciencedirect.com.wwwproxy0.library.unsw.edu.au/science/bookseries/00702153/92

Z3462474 (talk) 14:27, 26 August 2016 (AEST) Here are some reviews I have found that could be a helpful starting point:

Notch signalling at a glance: http://jcs.biologists.org/content/joces/126/10/2135.full.pdf

Signalling pathways for neural development: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369499/pdf/WJSC-7-437.pdf

Notch's role in diabetic neuropathy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677813/pdf/nihms473246.pdf

Notch in cardio development and disease http://circres.ahajournals.org/content/118/1/e1.full

Z5015014 (talk) 14:28, 26 August 2016 (AEST) here's the embryology site page for Notch signalling!

Z5015014 (talk) 14:31, 26 August 2016 (AEST) I also found a review article for Notch signalling in the common fruit fly, which could be a good idea for a subsection: PMID 12369105 General outlines of the molecular genetics of the Notch signalling pathway in Drosophila melanogaster: a review.

Z5015014 (talk) 14:44, 26 August 2016 (AEST) and here's some more reviews: PMID 22397947 Non-canonical Notch signaling: emerging role and mechanism and PMID 21828089 Notch signaling: simplicity in design, versatility in function.

Z5014803 (talk) https://www.researchgate.net/publication/264164124_Introduction_to_Notch_Signaling This seems like a good link for the history and discovery of the pathway

Z5014803 (talk) https://embryo.asu.edu/pages/notch-signaling-pathway-embryogenesis Can be used for introduction

Z3462474 (talk) 12:41, 19 August 2016 (AEST) Signalling in neural embryonic development looks interesting! Particularly the paper about NSCs and psychiatric disorders.

Z5015014 (talk) 21:59, 18 August 2016 (AEST): Hedgehog signalling (specifically SHH signalling) sounds really interesting!

Z5014803 (talk) 22:39, 18 August 2016 (AEST): Bone Morphogenetic Proteins (BMP) signalling in development looks interesting

Z3491219 (talk) I think looking at how in utero exposure to cigarette smoke affects fetal ovarian development signalling would be interesting.