Difference between revisions of "Talk:2015 Group Project 1"

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The page used a good amount of supporting pubmed articles, hwoever more images/media files could be used to break up the concentrated use of text. The video used is relevant and informative – however there is no copyright information.--[[User:Z5015534|Z5015534]] ([[User talk:Z5015534|talk]]) 22:44, 10 October 2015 (AEDT)
 
The page used a good amount of supporting pubmed articles, hwoever more images/media files could be used to break up the concentrated use of text. The video used is relevant and informative – however there is no copyright information.--[[User:Z5015534|Z5015534]] ([[User talk:Z5015534|talk]]) 22:44, 10 October 2015 (AEDT)
  
Hi guys! I'll start of by saying that the images and video you have included are excellent and are relevant to your topic of discussion. Also, you have a large number of reliable references which is good to see. However you have yet to include a hand drawn image, which is required for the wiki page. I feel like  you could probably eliminate the typed out 'timeline of mitochondrial donation' and instead use this as an opportunity to use a hand drawn image of the timeline. Furthermore, the timeline under 'cystoplasmic transfer' feels a bit awkward and unnecessary. You could probably include this timeline alongside the 'timeline of mitochondrial donation'.  
+
--[[User:Z3416054|Z3416054]] ([[User talk:Z3416054|talk]]) 11:12, 12 October 2015 (AEDT)Hi guys! I'll start of by saying that the images and video you have included are excellent and are relevant to your topic of discussion. Also, you have a large number of reliable references which is good to see. However you have yet to include a hand drawn image, which is required for the wiki page. I feel like  you could probably eliminate the typed out 'timeline of mitochondrial donation' and instead use this as an opportunity to use a hand drawn image of the timeline. Furthermore, the timeline under 'cystoplasmic transfer' feels a bit awkward and unnecessary. You could probably include this timeline alongside the 'timeline of mitochondrial donation'.  
  
 
Under the 'Technical Progression' section it would be best to incorporate human embryo, mouse and human models under a sub-sub heading, as at the moment it feels a bit jumbled.
 
Under the 'Technical Progression' section it would be best to incorporate human embryo, mouse and human models under a sub-sub heading, as at the moment it feels a bit jumbled.
  
 
I would also recommend moving the 'Benefits' heading towards the end of the page. It feels odd reading about the benefits of three person embryos before I gain a proper understanding of how they work. Also it might be worth talking about the disadvantages (if there are any) to three person embryos to balance out the 'benefits' section. As has been previously stated, make sure you sort out the copyright information for your video as it would be a shame to lose marks if it was missing. Also, don't forget to add the 'student template' to the 'Swapping mitochondrial DNA mammalian oocytes' image as it is currently absent.--[[User:Z3416054|Z3416054]] ([[User talk:Z3416054|talk]]) 11:11, 12 October 2015 (AEDT)
 
I would also recommend moving the 'Benefits' heading towards the end of the page. It feels odd reading about the benefits of three person embryos before I gain a proper understanding of how they work. Also it might be worth talking about the disadvantages (if there are any) to three person embryos to balance out the 'benefits' section. As has been previously stated, make sure you sort out the copyright information for your video as it would be a shame to lose marks if it was missing. Also, don't forget to add the 'student template' to the 'Swapping mitochondrial DNA mammalian oocytes' image as it is currently absent.--[[User:Z3416054|Z3416054]] ([[User talk:Z3416054|talk]]) 11:11, 12 October 2015 (AEDT)

Revision as of 11:12, 12 October 2015

2015 Projects: Three Person Embryos | Ovarian Hyper-stimulation Syndrome | Polycystic Ovarian Syndrome | Male Infertility | Oncofertility | Preimplantation Genetic Diagnosis | Students

Links to Project Discussion Pages: Discussion 1 | Discussion 2 | Discussion 3 | Discussion 4 | Discussion 5 | Discussion 6

This is the discussion page for your project.

  • Use this page to discuss online the project with your group members.
  • Paste useful resources here.
  • Remember to use your signature button to identify who you are when adding content here.
  • The following collapsed tables provide starting points for students during project work, you also have tutorials built into practical classes and practice exercises for individual assessmet items.
Group Assessment Criteria  
Mark Hill.jpg Science Student Projects
  1. The key points relating to the topic that your group allocated are clearly described.
  2. The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area.
  3. Content is correctly cited and referenced.
  4. The wiki has an element of teaching at a peer level using the student's own innovative diagrams, tables or figures and/or using interesting examples or explanations.
  5. Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities.
  6. Relates the topic and content of the Wiki entry to learning aims of embryology.
  7. Clearly reflects on editing/feedback from group peers and articulates how the Wiki could be improved (or not) based on peer comments/feedback. Demonstrates an ability to review own work when criticised in an open edited wiki format. Reflects on what was learned from the process of editing a peer's wiki.
  8. Evaluates own performance and that of group peers to give a rounded summary of this wiki process in terms of group effort and achievement.
  9. The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning.
  10. Develops and edits the wiki entries in accordance with the above guidelines.
More Information on Assessment Criteria | Science Student Projects
Uploading Images 
Mark Hill.jpg First Read the help page Images

The following describes how to upload an image with all the information that must be associated with it.

The image must first be uploaded to the site.

  1. Open the left hand menu item “Toolbox” and click “Upload file” and a new window will open.
  2. Click the button ”Choose file” and navigate to where the image is located on your computer and double click the file.
  3. The window will now show the file name in the “Source filename” window.
  4. You can then rename the uploaded file in the “Destination filename” window.
    1. Make sure the new name accurately describes the image.
  5. Add a description of the image to the “Summary” window. Note the description must include:
    1. An image name as a section heading.
    2. Any further description of what the image shows.
    3. A subsection labeled “Reference” and under this the original image source, appropriate reference and all copyright information.
    4. Finally a template indicating that this is a student image. {{Template:Student Image}}

Images not including the above information will be deleted by the course coordinator and be considered in the student assessment process.

Students cannot delete uploaded images. Contact the course coordinator with the file address.

Referencing 
Mark Hill.jpg First Read the help page Referencing

All references used in making your project page should be cited where they appear in the text or images.

In page edit mode where XXXX is the PubMed ID number use the following code.

<ref name=”PMIDXXXX”><pubmed>XXXX</pubmed></ref>

For references not listed on PubMed, and text can be inserted between <ref></ref> tags.

Where the reference list will appear make a new section and on a new line the following code. <references/>

Plagiarism 
Mark Hill.jpg First Read the help page Copyright Tutorial

Currently all students originally assigned to each group are listed as equal authors/contributors to their project. If you have not contributed the content you had originally agreed to, nor participated in the group work process, then you should contact the course coordinator immediately and either discuss your contribution or request removal from the group author list. Remember that all student online contributions are recorded by date, time and the actual contributed content. A similar email reminder of this information was sent to all current students.

Please note the Universities Policy regarding Plagiarism

"Plagiarism at UNSW is defined as using the words or ideas of others and passing them off as your own." (extract from UNSW statement on Academic Honesty and Plagiarism)

Academic Misconduct carries penalties. If a student is found guilty of academic misconduct, the penalties include warnings, remedial educative action, being failed in an assignment or excluded from the University for two years.


Please also read Copyright Tutorial with regard to content that can be used in your project.

2015 Group Project Topic - Assisted Reproductive Technology
ART in Australia (2012)

Some Potential Topics

  • Your own selected topic (consult coordinator)
  • oocyte quality
  • spermatozoa quality
  • prenatal genetic diagnosis
  • frozen oocytes
  • in vitro oocyte development
  • assisted hatching
  • cryopreserved ovarian tissue
  • oncofertility
  • 3 person embryos
  • fertility drugs
  • Ovarian hyperstimulation syndrome (OHSS)
  • ART for genetic disorders
  • male infertility
  • female infertility

Assisted Reproductive Technology

Journal Searches  
Below are shown some easy methods, with examples, for setting up simple searches of PubMed and other Journal databases. In most cases, you simply need to replace the existing term (embryo) where it appears in Wiki code with your own. Note there may also be additional "Advanced search" options available within these sites.


Students - read the paper first before committing to use/cite the material, to ensure you are using the information correctly and in context.


Reference Links: Embryology Textbooks | Journals | Journal Searches | Reference Tutorial | Copyright | For Students | UNSW Online Textbooks | iBooks | Journals | RSS Feeds | Online | Societies | Online Databases | Historic - Textbooks | Pubmed Most Recent | Category:References


Editing Links: Editing Basics | Images | Tables | Referencing | Journal Searches | Copyright | Font Colours | Virtual Slide Permalink | My Preferences | One Page Wiki Card | Printing | Movies | Language Translation | Student Movies | Using OpenOffice | Internet Browsers | Moodle | Navigation/Contribution | Term Link | Short URLs | 2018 Test Student


Please use the following as a guide:

  • Always when citing, identify reviews separately from original research articles.
  • Always identify copyright conditions allow your reuse of content before uploading.
  • If quoting text verbatim always include in "quotation marks" and reference, or additionally identify in brackets after the excerpt.


External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.

Database Example search Wiki code (note - copy text when in Read mode)
Pubmed (all databases) embryo [http://www.ncbi.nlm.nih.gov/sites/gquery?term=embryo ''embryo'']
Pubmed embryo [http://www.ncbi.nlm.nih.gov/pubmed?term=embryo ''embryo'']
Pubmed 5 most recent references[1] <pubmed limit=5>embryo</pubmed>
Pubmed Central embryo [http://www.ncbi.nlm.nih.gov/pmc/?term=embryo ''embryo'']
Pubmed Central (images) embryo [http://www.ncbi.nlm.nih.gov/pmc/?term=embryo&report=imagesdocsum ''embryo'']
PLoS (Public Library of Science) embryo [https://www.plos.org/?s=embryo&submit=Go ''embryo'']
BioMed Central embryo [http://www.biomedcentral.com/search/results?terms=embryo ''embryo'']
BMC Developmental Biology embryo [http://www.biomedcentral.com/bmcdevbiol/search/results?terms=embryo ''embryo'']
Biology Open (BiO) embryo [http://bio.biologists.org/search?submit=yes&titleabstract=embryo&andorexacttitleabs=and&fulltext=&submit=yes&submit=Submit ''embryo'']
About Journal Searches
The following general information is about the above online databases and journals.

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.

  • PubMed - comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
    • PubMed Central (PMC) - is a free full-text archive of biomedical and life sciences journal literature at the U.S. National Institutes of Health's National Library of Medicine (NIH/NLM).
  • Public Library of Science (PLOS) - is a nonprofit publisher and advocacy organization founded to accelerate progress in science and medicine by leading a transformation in research communication.
  • BioMed Central (BMC) - is an STM (Science, Technology and Medicine) publisher of 291 peer-reviewed open access journals.
    • BMC Developmental Biology - is an open access, peer-reviewed journal that considers articles on the development, growth, differentiation and regeneration of multicellular organisms, including molecular, cellular, tissue, organ and whole organism research.
    • Reproductive Health - is an open access, peer-reviewed online journal focusing on all aspects of human reproduction.
    • Reproductive Biology and Endocrinology (RB&E) - aims to act as a forum for the dissemination of results from excellent research in the reproductive sciences. RB&E represents a global platform for reproductive and developmental biologists, reproductive endocrinologists, immunologists, theriogenologists, infertility specialists, obstetricians, gynecologists, andrologists, urogynecologists, specialists in menopause, reproductive tract oncologists, and reproductive epidemiologists.
  • Biology Open (BiO) - is an online-only Open Access journal that publishes peer-reviewed original research across all aspects of the biological sciences, including cell science, developmental biology and experimental biology.
  1. Note the references appear where the code is pasted and will be updated each time the page is loaded, and may occasionally list articles that do not appear directly related to the search topic.


You can paste this template on your own page for easy reference. This current template is also available as a plain page.

Stem cell presentation

Hi, I have listed some papers which I am interested in doing because it is highly relevant to my own project. But I am more than happy if you post other papers and topics which interest you and we can work on them together and get ready earlier.

PMID 26295456

PMID 26439174

PMID 24837661

PMID 26418893

PMID 24981862

Useful resources

Here is a good source for overview and status of 3 Person IVF. http://www.geneticsandsociety.org/article.php?id=6527

Mitochondria

  • discovered in muscle by Kölliker in 1857
  • mitochondria are the "powerhouses" of the cell and the location where respiration occurs at the cellular level.
  • mitochondria contain their own DNA (mitochondrial DNA or mtDNA) that has been originally inherited only from the oocyte (maternal inheritance).
  • The spermatozoa (paternal) mitochondria- energy for fertilization motility but are generally destroyed during the first mitotic cell divisions.
  • This pattern of inheritance has important implications for a variety of mitochondrial associated diseases, usually occurring in tissues requiring lots of energy (muscle, brain).
Electron micrograph of mitochondria.

Eukaryotic mitochondrial genomes

  • double stranded circular DNA (mitoDNA. mtDNA)
  • 1981 complete human sequence (16,569 nucleotides)
    • 37 genes
    • encodes 13 polypeptides involved in oxidative phosphorylation
  • remaining genes transfer RNA (tRNA) and ribosomal RNA (rRNA)
  • multiple copies within the matrix
  • maternally inherited
  • remainder encoded by nuclear DNA
  • proteins made in cytosol and imported into mitochondria


link to Embryology website Mitochondria

Chat

--Mark Hill (talk) 11:13, 25 September 2015 (AEST) OK so just text on your page to date and not yet a thorough coverage of the topic. Animal models, timeline, images, diseases.

--Mark Hill (talk) 16:07, 21 August 2015 (AEST) I think you will have 3 students and therefore will exist as a group.

--Z3251292 (talk) 17:29, 21 August 2015 (AEST) hi all,sorry that I still could not make my way to uni today due to illness. I will definitely be back next week. I have added few sub-headings to the points you guys setup, feel free to change them. BTW, would you like to pick one of the 5 topics for now? and start working on it? or there was some good arrangement already? please let me know.

--Z3292373 (talk) 20:51, 24 August 2015 (AEST) Hey, ummm sorry i lead us astray putting up those headings female fertility had been taken so we have to pick another. I put up the list of ones left. My choice would be three parent ivf. So ill do a bit of research and on that now (add some headings)just 'cuase i got some free time, but by all means if you guys would like to do something else that interests you I'm more then happy to change.

--Z3251292 (talk) 13:19, 27 August 2015 (AEST) Hi all, I am good with your choice. let's work on 3 person embryo. i have added few papers I find good on this topic.

General

Note to self doing history benifits.

Section

Peer Reviews

This wiki page does well in covering a lot of areas relating to the topic, however the website does not outline the information found/used quite clear enough or to the right extent. The page would benefit largely in focusing much more attention to the mechanics of the process itself and how it physically works. There is lots of information regarding other various aspects relating to the topic, however the fundamentals of the topic are not clearly discussed on the page, and it is not clear what goes on in the process.

The page should also fix up some grammatical and syntax errors. Read through the page carefully and ensure all paragraphs make sense ensuring that the quality of the information portrayed is fully appreciated. To also make the page clearer, some thought should be given to rethinking the order of the subheadings. Having a natural cohesion throughout the page as a whole is important – some subheadings do not fit into place correctly and could be moved around a little bit. Also having linking sentences within paragraphs – involving each subheading with others and the topic as a whole – will make the page much more cohesive.

The page used a good amount of supporting pubmed articles, hwoever more images/media files could be used to break up the concentrated use of text. The video used is relevant and informative – however there is no copyright information.--Z5015534 (talk) 22:44, 10 October 2015 (AEDT)

--Z3416054 (talk) 11:12, 12 October 2015 (AEDT)Hi guys! I'll start of by saying that the images and video you have included are excellent and are relevant to your topic of discussion. Also, you have a large number of reliable references which is good to see. However you have yet to include a hand drawn image, which is required for the wiki page. I feel like you could probably eliminate the typed out 'timeline of mitochondrial donation' and instead use this as an opportunity to use a hand drawn image of the timeline. Furthermore, the timeline under 'cystoplasmic transfer' feels a bit awkward and unnecessary. You could probably include this timeline alongside the 'timeline of mitochondrial donation'.

Under the 'Technical Progression' section it would be best to incorporate human embryo, mouse and human models under a sub-sub heading, as at the moment it feels a bit jumbled.

I would also recommend moving the 'Benefits' heading towards the end of the page. It feels odd reading about the benefits of three person embryos before I gain a proper understanding of how they work. Also it might be worth talking about the disadvantages (if there are any) to three person embryos to balance out the 'benefits' section. As has been previously stated, make sure you sort out the copyright information for your video as it would be a shame to lose marks if it was missing. Also, don't forget to add the 'student template' to the 'Swapping mitochondrial DNA mammalian oocytes' image as it is currently absent.--Z3416054 (talk) 11:11, 12 October 2015 (AEDT)