Talk:2012 Group Project 5

From the Course Coordinator

2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing

--Mark Hill 09:58, 18 September 2012 (EST) This is a recent review on vision. http://jcb.rupress.org/content/190/6/953.full JCB content allows reuse.

http://www.jove.com/video/3730/isolation-and-culture-of-human-fungiform-taste-papillae-cells

--Mark Hill 08:17, 16 August 2012 (EST) This small section at the top of your discussion page allows me to easily distribute information to all students looking at the group discussion page.

Please do not delete, edit or move the template {{Template:2012GroupDiscussion}} from the top of this page.

1. Search:

• http://www.ncbi.nlm.nih.gov/sites/gquery?term=embryo Pubmed search all databases term embryo, replace this with your own term to set up a search on your topic.
• http://www.ncbi.nlm.nih.gov/pmc/?term=embryo&report=imagesdocsum Pubed Central search for images using the term embryo, replace this with your own term to set up a search on your topic.

2. History

• Embryology History Explore the rich history of sensory research. In particular look through the available images that may complement the text. Any of this material can be used, you should cite the original paper or textbook. Gray | 1921 Bailey and Miller

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Group evaluation

Your introduction is quite short, but it does state what you will be discussing on your page. You might want to include the normal development in the introduction, to allow for an overview of what normally happens before you actually start on the abnormal development. It just seems a little odd that you have abnormal vision as you title and then almost immediately after that you have a normal eye development heading.

I really like the chronological order used in the normal development section. It might be a bit easier to read if you use dot points. References seems to be fine, however, 4 and 5 are the same. It might also be useful to create a link to the group page on normal vision development.

Abnormal development consists of a few subheadings. Personally, I would delete the lines below the different subheadings. It will make it look more like one section on abnormal development. I think it was a good idea to look at the different parts of the eye related to abnormalities – lens, cornea, retina, etc. You look at different genes which play an important role at a certain developmental stage and you explain the resulting effects. I can see a lot of research has been done on this section. Images will need to be made bigger. They look insignificant with this size and it just seems like the text is going on and on. A lot of terms mentioned in this section are not included in the glossary, eg. Dysgenesis, substantia propria, CRX (what does it stand for?). Please add these in. Again, check your references, because some are the same, eg. 8 & 9.

Ocular manifestation is part of the abnormal development section (I think), so please make sure you show this with the headings. Again, immediately below this seems to be another heading with genetics, which has nothing included… or does LCA belong to genetics? I am a bit confused due to all your different headings and lines which seem to separate parts that may potentially belong together.

In your LCA section I would change the order of text a little: definition (as you have at the start), then epidemiology (which you have at the bottom), then the section on Dr Leber (up to “…placing great emphasis upon the high incidence of hereditary factors.”), lastly a new paragraph on the diagnosis (“As stated in the section on… diagnostic protocol for LCA”). The link to Abnormal Retinal Development does not work and will need editing. I can see that your timeline refers to LCA in particular and it is quite expansive. The one reference provided leads to a website with a timeline that seems to have been copied and pasted into your project. Please change this into your own words and (where possible) provide references to the original papers. The table also seems to be located in a strange position and it may be better to include this information in a table on history (in general), which you do not have at the moment. New research development also focuses on LCA only. Maybe create a separate section at the end where you can mention this and include more current research in brief paragraphs. The image relates well and has the appropriate citation, copyright and student template. The description could include a little more information.

Anophthalmia and microphthalmia are other genetic abnormalities described. Again, with the image you can expand slightly upon the description, but besides that it relates well to your text. Information provided is good, and includes the clinical description, genetic causes and management. Most important is that you use the same layout for your headings throughout your project. Within this one section you are using different subheadings and it all looks a bit chaotic and makes it less encouraging to read. You explain the role various genes play and I would like to know at what week/gestational stage they are important and can cause these abnormalities. Make sure all your references are correct, eg. There is no reference for 30.

It is probably good you only focused on 2 abnormalities caused by environmental factors. Images could really complement the text (although your whole page could probably use a few more images), so please add these. You include some relevant information and statistics, but make sure you also keep adding to the glossary. References are also the same for 45-48, hence these need editing.

In my opinion, firstly change the layout of your page and make it more organised with logical headings. Then focus on some of the other things mentioned above.

Hope this helps!

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Discussion

Hey so what organ did everyone decide on heart or liver. I vote for the Liver

Hi Team! I would first like to apologize for not coming on Wednesday on our practical. So I am sorry one more time for that. I am coming to practicals this Wednesday so we can discuss our topics. Just to ask what happen on Wednesday in regards of our group project? So we need to decide between heart or liver to write our project? If that is so...I vote for the heart then:)

remember to sign after contributions to this page

Hey kidlings, just to let you know, I'm going to be looking through my path/grey's anatomy textbooks for anything i can possibly find. I think we should start with a little intro of what is the normal development and then have some abnormalities that can stem from that? Thoughts? --Z3374173 19:17, 21 August 2012 (EST)

Hey Team, some ideas for the focus of our topic. 1. a basic overview of the development of the eye, 2. divide the eye up into it regions of development and look at the abnormalities that can occur, including the factors which make it abnormal: congenital or defect; percentage of occurance in society and/or likely hood aquiring it; processes of the abnormal development (how abnormaility occurs); living with the abnormality; any treatments and/or prevntions for the abnormality. --Z3220343 19:31, 21 August 2012 (EST)

Possible sources: [1] [2] --Z3374173 10:12, 22 August 2012 (EST)

Textbook: The Developing Human Chapter 20 [3] --Z3220343 10:14, 22 August 2012 (EST)

Looking through textbooks, I have found Retinoblastoma which is a tumor usually in the posterior retina. It says it can occur in 2 year olds but also can occur at birth, so that could be a developmental one. I found that in my pathology textbook, Others i found could be Horner's syndrome, that apparently can start developing in fetal development. I'll go through my mums old midwifery textbooks too. Anyone else find anything?--Z3374173 16:49, 26 August 2012 (EST)

Hey so i was looking through the textbook and i found a list of defects of the retina. further down it also talks about congenital glaucoma. [4] i found this while surfing pubmed may be of some use?[5] i had heard of a genetic disorder in which if both parents are carriers the baby has 25% chance being born blind. i think this was the disorder if not, it still could be interesting for our assignment [6][7][8]--Z3220343 21:09, 28 August 2012 (EST)

I think I shall do Horner's Syndrome. [9]--Z3374173 11:29, 29 August 2012 (EST)

Hi team :D I just found an article that talks about all the current knowledge on conditions related to abnormal visual development in infants. In the article, they have aslo included prevalence, risk factors and mechanisms that are involved with the development of these conditions. I think it would be quite useful to our own topic. Just letting everyone know, i will be doing congenital cataracts. [10]--Z3331330 12:36, 29 August 2012 (EST)

Heres another article description of the normal visual development, each component of the visual system is included and explained very clearly, this would be useful for our general overview on the development of the eye. In particular, the retina development is also mentioned in the article which we can make use of when comparing our disorder with the normal development. [11]--Z3331330 12:47, 29 August 2012 (EST)

Hey Guys, After trawlling through stacks of info on Horner's syndrome I'm not satisfied with the amount of info there is so I'm going to change it up and try Chorioretinal Scars. I can find more information and really hope this comes together!! --Z3374173 21:34, 10 September 2012 (EST)

I did the normal development, feel free to check it over, make changes etc, I have the PDF files of the articles i used if you need to check. Also, I've forgotten how to make all the reference bind together if they are the same text, i cant seem to find the help to help me so I'm just going to leave it until someone can help me! --Z3374173 17:07, 12 September 2012 (EST)

hey team, do u guys think that we have enough information? what else should we add in if we do need some more.--Z3331330 22:00, 17 September 2012 (EST)