Talk:2012 Group Project 2

From the Course Coordinator

2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing

--Mark Hill 09:58, 18 September 2012 (EST) This is a recent review on vision. http://jcb.rupress.org/content/190/6/953.full JCB content allows reuse.

http://www.jove.com/video/3730/isolation-and-culture-of-human-fungiform-taste-papillae-cells

--Mark Hill 08:17, 16 August 2012 (EST) This small section at the top of your discussion page allows me to easily distribute information to all students looking at the group discussion page.

Please do not delete, edit or move the template {{Template:2012GroupDiscussion}} from the top of this page.

1. Search:

• http://www.ncbi.nlm.nih.gov/sites/gquery?term=embryo Pubmed search all databases term embryo, replace this with your own term to set up a search on your topic.
• http://www.ncbi.nlm.nih.gov/pmc/?term=embryo&report=imagesdocsum Pubed Central search for images using the term embryo, replace this with your own term to set up a search on your topic.

2. History

• Embryology History Explore the rich history of sensory research. In particular look through the available images that may complement the text. Any of this material can be used, you should cite the original paper or textbook. Gray | 1921 Bailey and Miller

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--Mark Hill 09:57, 18 September 2012 (EST) This is a recent review on touch. http://jcb.rupress.org/content/191/2/237.full JCB content allows reuse.

Group evaluation

- The introduction is small yet detailed --- I like how its an overview of the development. You do need to fix up the references though.

- You have in the intro section “the following picture….” But there is no picture there….if the picture is further ahead maybe write Fig 1 shows….and also label the picture.

- History section needs a bit work on – you should start with the earliest data and proceed in a chronological order so everyone can see the advancement in development of somatosensory organs.

- In the section of “Development of the primary somatosensory cortex” you have mentioned that there are intrinsic and extrinsic mechanisms --- you should mention what those signalling mechanisms are. Also if you are using the one ref for the whole paragraph do not put the ref after each line. Just put it in the end. Also it would be good to give the origin of the neurons like ecto, endo or meso.

- Its good how your description is divided into stages – it might help to give the weeks as well.

- For the touch section you have a lot of detail on what the receptors are which is fine but there is nothing about their development (which is what the project is about). The same thing is noted with “Pain” section – there is nothing on development. I’m sure you can put some genes or signalling molecules that are important for differentiation of cells into the different receptors.

At the moment your project is focused on what the different somatosensory receptors do but very little detail on how they develop, which is what you need to focus on.

More pictures are needed to break up the text.

Good luck!

--Z3333794 09:51, 23 September 2012 (EST)

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Your introduction is quite expansive and the first paragraph gives an excellent overview of what the somatosensory system actually is. At the end of the first paragraph you do refer to a picture; however, there is no picture. Please add this to show the somatosensory organisation within the body. In the second paragraph you mention some key timepoints related to the somatosensory development, which is good. After this (“Development of the system entails…lemniscal system.”) the text is probably too specific for the introduction. This can be used as an introduction for your development subheading. Please make sure that you edit the in-text references to proper references which we can access via your reference list. Also make sure you start adding terms to the glossary, eg. dorsal column-medial lemniscal system (I do not know what this means!)

You have started on your history section, but it would be more interesting and easier to read if you put this in a table. For instance: date – description – significant person. Also try to add a few more important discoveries. Again, please provide proper references. See the ‘editing basics’ section on this embryology website.

The central somatosensory differentiation is good and I can see that a lot of effort has been put into this section. The picture is very helpful and complements the text. To some extend it does seem like the sensory neurons only come from the dorsal aspect (going into the dorsal root ganglion), so maybe put a note in there that the dorsal and ventral rami are mixed nerves and both of them will contain sensory neurons that go to the dorsal root ganglion. With this image, you also have to include the student template. Text and references are good in this section and I particularly found the ‘making connections’ section very clear, organised and enjoyable to read. Do make sure that you add to the glossary – in particular terms from the ‘development of the primary cortex section’, and if possible add more images.

The touch section has a fair amount of text, but no images to complement it. This made it a bit boring to read. Make sure the subheadings stand out by making them bold. Most of the text has not been references at all, which is concerning and could potentially indicate plagiarism. I also did not read anything about the development of the various receptors (or hypotheses it no distinct evidence has been provided yet). Keep in mind we are looking at the development of the system, not the physiology. You did put in some interesting facts, such as that cell abnormalities can lead to Merkel-cell carcinoma.

Pain and hot/cold are similar to touch: good description of the physiology, but no development included. References are only provided as in-text citations or listed below, which will need to be edited to include them into the reference list. Include images to complement your text and engage the reader – this also concerns the touch section.

The pressure section has limited information regarding the development. Please include how this develops – what factors are included etc. In my opinion there is too much focus on the adult physiology. We are studying embryology… As mentioned above, please edit references and include appropriate images.

Current research looks good with an interesting image and the appropriate references, copyright and student template. The description helps to understand the image. Maybe add another research project to this section.

Add to the glossary, references and actually name the external links listed as 1) 2) and 3).

Hope this helps!

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The introduction is very detailed and precise, and it really prepares the readers for what is going to be covered within the project. I thought it was a good introduction but the referencing needs to be fixed up because it looks really different too all the other parts of the project. I do not think that style of in-text citation is needed for the purpose of this project. The histories of discoveries will look better if it is in dot-points, it would be so much easier to read.

In the central somatosensory differentiation section, you mentioned that there are three components, but to me, only the primary somatosensory cortex has been extensively researched, i think more research should be done on the other two components. There is an imbalance of information between the three components. Also, I can see that only 2 references have been used in this entire section, maybe this is why there is an imbalance of information. Using a large variety of resources will definitely expand your knowledge and enable you to put in more information in this section. I thought the hand-drawn image was impressive but the colour is a bit vague and hard to see. A larger version of the image should be uploaded so that it is easier to see.

The "making connection" section has very good description on the physiology and the signalling process of CNS but I do not really understand the stages? Are they the stage events that are involved in embryonic development? Some more detailed explanation is needed here, and maybe some images will help?

The touch section has some good information but again only 2 references have been used which shows the need for further research. Images should be put in here because right now it is very crowded with text. Also, the same problem keeps occurring throughout the project, I feel like there are lots of information about the function of different components of the somatosensory system but not how they are developed. Make sure you do not go off track. There are some weird referencing in the hot/cold section which needs fixing up. There are nothing in the glossary, scientific terms and definition should be put here because not everyone will understand the terms used within the project page. The structure of the project was good though, very clear and simple which makes the page very easy to follow.

Overall, the page is looking good but maybe more research should be done and more images should be put in to balance with the large amount of text. Also, keeping the information related to the research topic will be a huge aspect to focus on.

Group Assessment Criteria:

1. The key points relating to the topic that your group was allocated are clearly described. The introduction outlines the importance of the somatosensory system and provides a good summary of the developmental stages. More emphasis could be made on the key points of the project page.
2. The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area. The content shows an understanding of the topic area, however the layout makes the text difficult to follow. There is not a clear connection between the ‘Central Somatosensory Differentiation’ and the somatosensory system. There is a lack of diagrams, tables and graphs to explain the written content.
3. Content is correctly cited and referenced. Some sections are correctly referenced whilst others are completely lacking. This area needs working on.
4. The wiki has an element of teaching at a peer level using the student’s own innovative diagrams, tables or figures and/or using interesting examples or explanations. The information is broken down well by headings and subheadings, however there is a lack of relating images to compliment the information. The one student drawn image is very useful.
5. Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities. The information provided is well researched and satisfies the aims of the project in terms of developmental stages, however in order to go ‘beyond the formal teaching activities’ it needs to include sections such as abnormal development and more on the history, current and future research.
6. Relates the topics and content of the Wiki entry to learning aims of embryology. The topics and content relate to the learning aims of embryology by describing the developmental stages if the somatosensory cortex.
7. The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning. There has been a fair amount of research into the topic, however a bulk of the information is focused on descriptions of each of the senses. More emphasis should be placed on the development of each of these sense as that is the key topic area.

Additional points:

• The Introduction and Central Somatosensory Differentiation sections were well written and the accompanying diagram was very useful.
• The layout of the page could be improved with the use of tables and diagrams to reduce/replace the amount of text
• The project seems largely incomplete; more research needs to go into the History and research sections and there is a lack of images

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Search

Hi, whoever wrote the history section, can you include some dates as to when the discoveries were made. I was thinking of putting that info into a table but we need the dates to do that. Thank you. --Z3332863 14:50, 15 September 2012 (EST)

search pubmed GTO development

Development of Nociceptors, Thermoceptors,and Pruriceptors

Lopes C, Liu Z, Xu Y, Ma Q. Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15. <pubmed>22787056</pubmed>

Review for general Somatosensory development - just for background knowledge:

<pubmed>7812142</pubmed> --Z3332863 14:53, 23 August 2012 (EST)

Central sensory Neuron development:

<pubmed>2918087</pubmed> --Z3332863 14:53, 23 August 2012 (EST)

Article on Pain Development:

<pubmed>16446141</pubmed>

--Z3332863 10:05, 22 August 2012 (EST)

I think it would be cool to do an organ, but i'll be just as happy to do one of the senses. Does anyone have a specific organ they were thinking of?

My preference was Sensory, but if we get organ that's fine also. If we did do organ I still want to look into some of the topics before I give my opinion, depending on the research and information behind it. If we got sensory, sight could be cool? - ==Z3330539 08:26, 10 August 2012 (EST)==

I'd prefer Sensory.

I agree; if we got Sensory, I would be happy to do Sight. But if we got Organ, I want to do the Heart but I'd be just as as happy to do another organ if anyone's keen. --Z3332863 09:14, 10 August 2012 (EST)

Hi all,

I started with; and have mainly been looking into development relating to "Touch" and the receptors involved and time at which this occurs. I am happy to keep going or do research on the other categories as well? I will share what I found when we meet next. --Z3330539 22:02, 20 August 2012 (EST)--