Talk:2010 Group Project 6

Co-ordinator Comments

--This is an area for members of the group to communicate online and to place links and information relevant to the project. Do not forget to sign your additions and always add the newer material to the top of this page.

Projects: 1 | 2 | 3 | 4 | 5 | 6 | Students Page | Help:Editing Basics

--Mark Hill 22:56, 11 August 2010 (UTC) Well group 6 where is your work that should have been done before this week's Lab?

Hey guys, ive only really done some light background research about alpha-fetaprotein testing via wiki/google/journal articles hehe :P

Anyway, i forgot to save the links i got for the journal articles ive already printed off, but i’ll stick up their titles which can be found easily, and i’ll basically summarise the info we can use from them anyway and stick it up so we can sift through it all.

The journal articles that i remembered to save links to are as follows:

First-trimester maternal serum alpha-fetoprotein as a marker for fetal chromosomal disorders - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970141012/abstract

Amniotic fluid alpha-fetoprotein is not a useful biological marker of pregnancy outcome - http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0223%28199911%2919:11%3C1031::AID-PD684%3E3.0.CO;2-7/abstract

The value of early third-trimester maternal serum alpha-fetoprotein determination - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970100308/abstract

Reduced fetal hepatic alpha-fetoprotein levels in Down' s syndrome - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970101108/abstract

Very low versus undetectable maternal serum alpha-fetoprotein values and fetal death - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970070605/abstract

I don’t know what you guys had in mind for splitting the work etc, but as it is, im quite happy to just get info, and slowly just add info the main page as it goes and let it slowly evolve from constant editing of stuff etc. And if anyone had clashes of ideas etc, then just fix/change a section and stick it up as well and we can all just edit passages as we see fit after some discussion hehe

so you guys know what other articles im looking at, so we don’t really double up on info, are as follows: The effectiveness of prenatal serum biomarker screening for neural tube defects in 2nd trimester pregnant women

Msaf values in type ½ diabetic patients

2nd trim. Msaf elevation and its association with adverse maternal/fetal outcome

Afp in the early neonatal period

Structure and function of afp

ps - i most likely will just play around with headings etc on the main page...and if i put info up there in point form its not really the main text, just a quick point of ref. for what info i may or may not stick up etc as well as just general format testing haha ^_^

--3186755 15:56, 14 August 2010 (UTC)

Hi everyone, yeh I think its a good idea to compile information and research before the next lab and go through it together before we designate certain areas to one another. I'll try to get through some of the articles that are up to get an idea of how we are going to divide the work up. Possible categories:

1) Introduction to how it is carried out, history, developements. 2) How the test works, what is used or tested. 3) What the test is looking for, diseases, syndromes, dissorders. 4) Any problems or flaws the test has, effectiveness, contempory issues.

We should discuss more in depth during the lab, put up any more ideas for subheadings that we should use.

Thanks

--3290040 12:31, 17 August 2010 (UTC)

Hey guys,

I’m still in the research stage with this assignment, I think we really need to come up with a specific outline or structure for the assignment so the work can be divided up soon.

This structure is similar to the previous one mentioned above:introduction and background information on prenatal testing, what is alpha-fetoprotein how it is made by the foetus etc, the diseases that could be tested, history of maternal alpha- fetoprotein testing, accuracy etc.I don’t think there is much information on the procedure or ethical issues on this topic as they are not so relevant.

Here are two links The first one is some general research done on rats. I’m not sure if you guys want to use it?!!

www.reproduction-online.org/cgi/reprint/48/1/1.pdf

reducing invasive testing by using maternal serum alpha-fetoprotein testing. We could use it to compare some benefits of a non-invasive test.

http://www.nejm.org/doi/pdf/10.1056/NEJM199404213301603

--z3254433 11:28, 17 August 2010 (UTC)

Hey guys,

I think right now we have come up with the basic lay out of the site, I suggest that we split up the parts in our next lab class and if we come across anything that are specific for our assignment and think it's worthwhile to put in the site as well we can do that as we go along. These are some of the articles that I have been looking at:

MATERNAL SERUM ALPHA-FETOPROTEIN MEASUREMENT: A SCREENING TEST FOR DOWN SYNDROME - http://storage0.nun.unsw.edu.au/cgi-bin/Data/db.cgi?db=fulltexttest&uid=default&view_records=1&url=http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SFX&_method=citationSearch&_volkey=01406736%23323%23926&_version=1&md5=b96bddefb297298958f38399471d082b&Address=http://www.sciencedi

MATERNAL SERUM α-FETOPROTEIN—A MARKER OF FETAL APLASTIC CRISIS DURING INTRAUTERINE HUMAN PARVOVIRUS INFECTION - http://storage0.nun.unsw.edu.au/cgi-bin/Data/db.cgi?db=fulltexttest&uid=default&view_records=1&url=http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SFX&_method=citationSearch&_volkey=01406736%23329%23433&_version=1&md5=e7e29728e20dd0ed4956e51eb02c2128&Address=http://www.sciencedi

PRENATAL DIAGNOSIS OF SPINA BIFIDA AND ANENCEPHALY BY MATERNAL SERUM-ALPHA-FETOPROTEIN MEASUREMENT : A Controlled Study - http://storage0.nun.unsw.edu.au/cgi-bin/Data/db.cgi?db=fulltexttest&uid=default&view_records=1&url=http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SFX&_method=citationSearch&_volkey=01406736%23303%23765&_version=1&md5=bc4a8ecfac6aea060269fd3858638b59&Address=http://www.sciencedi