Talk:2010 Group Project 6

From Embryology
Revision as of 00:31, 23 September 2010 by Z3224500 (talk | contribs)

Peer review

GROUP 6: Maternal serum alpha-fetoprotein

I liked the overall scientific feel of the information you provided. I liked how you went into a bit of the molecular biology involved, as well as pictures to explain what exactly is alpha-beta protein. you guys showed a good understanding of the topic, although I noticed an error in the contents section where you put all the other headings under the 'introduction'. I liked the drawn pictures, it was a nice effort and was very informatively labelled. Ways to improve is probably add some tables to there isn't as much text and to simplify things, and also it can make it more interesting than it is already. More pictures in the abnormalities would have been good, images of spina bifida are definately eye catching and interesting to know about. The tables as pictures were a little hard to see without clicking on them but yes, good organisation, great job! --z3224500 13:31, 22 September 2010 (UTC)


To tell you the truth I didn’t find anything wrong with this assignment page. There is a lot of information but that can be expected from an informative web page. Yet the best way to make it look less is just throw some pictures into the mix. I think that your page was the only page that didn’t have any spelling mistakes so good work in that department and keep it up. I sometimes thought in some areas that the language was a bit easy to read and this can be both an advantage or a disadvantage depending on how Mark Hill but as a precaution just add a bit more scientific data. I don’t think it will hurt. I felt that in some place maybe a table would better suit the information presented but that just me. I also found the introduction had things that could be covered in sections below but I’m not sure if that was intentionally done. The best way to reduce the amount of words used to describe is to dot point or tabulate coming back to my old point but apart from that I found the assignment very informative and interesting which really isn’t easy when you have all those word, most people would have rambled on. So hats off to you there. The flow of the page is disrupted but you can fix that up by just moving bits and pieces around the page seeing where it fits best. A really good assignment. Well Done Guys!!!!

--z3252635 13:24, 22 September 2010 (UTC)


Hi guys!

Good job with the referencing and copyright information on your pictures, including the student-drawn ones. It would be nice to see descriptions of the pictures in that caption-area, just to make it more clear what part of your writing they were relating to. I love that you included a link to a video in your intro; it made me want to watch and find out more. I would suggest moving your other links for further reading to before your glossary though, just so they don’t get lost in the page – once people hit the glossary I find they tend to think that’s the end and stop reading (at least I tend to). Other than that, it says “ babys’ ” instead of “baby’s” in the Maternal Serum Alpha Protein as a Screening Test section first paragraph; but other than that I didn’t spot much else in the way of typos, and I found your language quite easy to read. Other suggestions would just be maybe to break up the text a bit, perhaps with some more pictures, just to make the page more eye-catching. Perhaps something with colour, if you can find it. Overall, though, well done!--z3252833 12:46, 22 September 2010 (UTC)


Group 6

Group 6, I think the structure of your page is great, there's enough subheadings to break it into clear sections, but maybe more point form could be used to break it up a little. The information is very detailed so it shows lots of research but its written in a clear enough way to be understandable, and it has a good scientific feel. The student drawn diagrams, especially the one of the analysis process, is great and helps to explain the information really well. What would improve this project: Maybe some more references, and you could also put in a section of the historic background of the procedure with some of the information that's in the introduction.

--z3292208 08:00, 22 September 2010 (UTC)


Maternal serum alpha-fetoprotein

This is a great project filled with lots of information. It is clearly well researched and the organisation of the page itself is sensible in the logical order of sub headingsand the flow of ideas.

I don't mind seeing a picture aligned to the left :P. Maybe you could use figures the break up the text a bit more? Other than that great work guys, this is excellent and gives a very 'scienfitic feeling'presentation of this topic

--z3254753 17:26, 21 September 2010 (UTC)


Group 6 = Maternal serum alpha-fetoprotein

The project is very organised and the pictures included were very related to the text. I really liked the link too because that not only showed you did alot of research for this project but also made it outstanding. Definetly provide me with better understanding About MSAFP.

How you can improve = There are alot of words may be try to break them down into point form but other than that everything looks good --Navneet Ahuja 12:16, 21 September 2010 (UTC)


Hi Group 6, I like how you have organised the page, its easy to follow and the layout was great. The pictures helped me with understanding the sections, although maybe they could be a bit bigger. I did learn alot about Maternal serum alpha-fetoprotein from your page, Thanks!

Improvements: Under the heading MSAFP testing and the community, there is a spelling mistake. liklihood should be likelihood, and servey should be survey. The page also looks a bit like an essay, maybe for some parts you could do a few tables to make it easier to follow

--z3265772 03:45, 21 September 2010 (UTC)

I enjoyed reading this project, the layout was overall great and i liked how you put in a link to a video. It was very understandable and i was able to follow what was said throughout reading it all. It was scientific enough but easy for anyone to read.

Improvements - the pictures were a little small, so maybe enlarge them a bit. Also, maybe break the procedure section into the different steps that are taken.

--z3291079 10:20, 21 September 2010 (UTC)

There is A LOT of information. Although it is very well researched (to that I commend you), I personally think you need to break it up a bit. Maybe align the pictures differently; they are great pictures they just seem to hang there as a side thought. Maybe also include a table or flow chart for the procedure because it is quite hard to follow. Your glossary is adequate although your referencing may fall short in the screening test section. Great video to start off with!! Good work guys!! --z3252083 12:45, 22 September 2010 (UTC)

Co-ordinator Comments
--This is an area for members of the group to communicate online and to place links and information relevant to the project. Do not forget to sign your additions and always add the newer material to the top of this page.

Projects: 1 | 2 | 3 | 4 | 5 | 6 | Students Page | Help:Editing Basics



--Mark Hill 00:56, 31 August 2010 (UTC) OK guys, its now time to get going with this. You need to have significant content added to all sections on your project page before this weeks lab. Still no related images or student drawn figure here.

You need to have this updated before this weeks lab when I will be reviewing all projects.

--Mark Hill 04:52, 23 August 2010 (UTC)OK so there is some discussion here. I need the major subheadings to be added before this weeks lab and there should be some thought to the content within each section. Still no related images here.


--Mark Hill 22:56, 11 August 2010 (UTC) Well group 6 where is your work that should have been done before this week's Lab?

Hey guys, ive only really done some light background research about alpha-fetaprotein testing via wiki/google/journal articles hehe :P


Anyway, i forgot to save the links i got for the journal articles ive already printed off, but i’ll stick up their titles which can be found easily, and i’ll basically summarise the info we can use from them anyway and stick it up so we can sift through it all.


The journal articles that i remembered to save links to are as follows:

First-trimester maternal serum alpha-fetoprotein as a marker for fetal chromosomal disorders - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970141012/abstract


--Mark Hill 04:54, 23 August 2010 (UTC) Here is the Pubmed link for the above paper http://www.ncbi.nlm.nih.gov/pubmed/7534926 This is how to cite it using the current website (look at the page in edit mode):

<pubmed>7534926</pubmed>


And this is how to reference it in the body of your project page.[1]


to appear in a reference list

  1. <pubmed>7534926</pubmed>



Amniotic fluid alpha-fetoprotein is not a useful biological marker of pregnancy outcome - http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291097-0223%28199911%2919:11%3C1031::AID-PD684%3E3.0.CO;2-7/abstract

The value of early third-trimester maternal serum alpha-fetoprotein determination - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970100308/abstract

Reduced fetal hepatic alpha-fetoprotein levels in Down' s syndrome - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970101108/abstract

Very low versus undetectable maternal serum alpha-fetoprotein values and fetal death - http://onlinelibrary.wiley.com/doi/10.1002/pd.1970070605/abstract

I don’t know what you guys had in mind for splitting the work etc, but as it is, im quite happy to just get info, and slowly just add info the main page as it goes and let it slowly evolve from constant editing of stuff etc. And if anyone had clashes of ideas etc, then just fix/change a section and stick it up as well and we can all just edit passages as we see fit after some discussion hehe


so you guys know what other articles im looking at, so we don’t really double up on info, are as follows: The effectiveness of prenatal serum biomarker screening for neural tube defects in 2nd trimester pregnant women

Msaf values in type ½ diabetic patients

2nd trim. Msaf elevation and its association with adverse maternal/fetal outcome

Afp in the early neonatal period

Structure and function of afp

ps - i most likely will just play around with headings etc on the main page...and if i put info up there in point form its not really the main text, just a quick point of ref. for what info i may or may not stick up etc as well as just general format testing haha ^_^

--3186755 15:56, 14 August 2010 (UTC)

Hi everyone, yeh I think its a good idea to compile information and research before the next lab and go through it together before we designate certain areas to one another. I'll try to get through some of the articles that are up to get an idea of how we are going to divide the work up. Possible categories:

1) Introduction to how it is carried out, history, developements. 2) How the test works, what is used or tested. 3) What the test is looking for, diseases, syndromes, dissorders. 4) Any problems or flaws the test has, effectiveness, contempory issues.

We should discuss more in depth during the lab, put up any more ideas for subheadings that we should use.

Thanks

--3290040 12:31, 17 August 2010 (UTC)


Hey guys,

I’m still in the research stage with this assignment, I think we really need to come up with a specific outline or structure for the assignment so the work can be divided up soon.

This structure is similar to the previous one mentioned above:introduction and background information on prenatal testing, what is alpha-fetoprotein how it is made by the foetus etc, the diseases that could be tested, history of maternal alpha- fetoprotein testing, accuracy etc.I don’t think there is much information on the procedure or ethical issues on this topic as they are not so relevant.

Here are two links The first one is some general research done on rats. I’m not sure if you guys want to use it?!!

www.reproduction-online.org/cgi/reprint/48/1/1.pdf

reducing invasive testing by using maternal serum alpha-fetoprotein testing. We could use it to compare some benefits of a non-invasive test.

http://www.nejm.org/doi/pdf/10.1056/NEJM199404213301603

--z3254433 11:28, 17 August 2010 (UTC)

Hey guys,

I think right now we have come up with the basic lay out of the site, I suggest that we split up the parts in our next lab class and if we come across anything that are specific for our assignment and think it's worthwhile to put in the site as well we can do that as we go along. These are some of the articles that I have been looking at:

MATERNAL SERUM ALPHA-FETOPROTEIN MEASUREMENT: A SCREENING TEST FOR DOWN SYNDROME - http://storage0.nun.unsw.edu.au/cgi-bin/Data/db.cgi?db=fulltexttest&uid=default&view_records=1&url=http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SFX&_method=citationSearch&_volkey=01406736%23323%23926&_version=1&md5=b96bddefb297298958f38399471d082b&Address=http://www.sciencedi

MATERNAL SERUM α-FETOPROTEIN—A MARKER OF FETAL APLASTIC CRISIS DURING INTRAUTERINE HUMAN PARVOVIRUS INFECTION - http://storage0.nun.unsw.edu.au/cgi-bin/Data/db.cgi?db=fulltexttest&uid=default&view_records=1&url=http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SFX&_method=citationSearch&_volkey=01406736%23329%23433&_version=1&md5=e7e29728e20dd0ed4956e51eb02c2128&Address=http://www.sciencedi

PRENATAL DIAGNOSIS OF SPINA BIFIDA AND ANENCEPHALY BY MATERNAL SERUM-ALPHA-FETOPROTEIN MEASUREMENT : A Controlled Study - http://storage0.nun.unsw.edu.au/cgi-bin/Data/db.cgi?db=fulltexttest&uid=default&view_records=1&url=http://www.sciencedirect.com/science?_ob=GatewayURL&_origin=SFX&_method=citationSearch&_volkey=01406736%23303%23765&_version=1&md5=bc4a8ecfac6aea060269fd3858638b59&Address=http://www.sciencedi

Alpha-fetoprotein Information, chemical composition, quantition, Standardization of AFP assay etc. - http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3083.1978.tb03896.x/pdf

Overview - http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B83W2-4TX314K-5&_user=1975841&_coverDate=09%2F30%2F2008&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000004218&_version=1&_urlVersion=0&_userid=1975841&md5=a7bfedcf9c80ddcf5994434da0c82603&searchtype=a

--3216889 10:56, 18 August 2010 (UTC)

hey guys,

i just put up a very rough and incomplete outline of the subheading that we can have for our assignment, so if you have any subheading you would like to add or edit those that i have put up please do so.

also if anyone has any relevant picture that we can use please post them up.

cheers.

--z3254433 23:55, 24 August 2010 (UTC)

hey, i just stuck up some basic background stuff on afp that is prety much just a dump of info so we can use it how we see fit :) hopefully will be able to add some other stuffs under the diff headings etc ^_^

--3186755 14:16, 25 August 2010 (UTC)

hey guys, just sending you a pictures via email that i drew but i think it might breach copyright so if you can edit it so that its not that would be great, also I'm uploading other pictures that i have drawn on our site. if you find any pictures that aren't copyright please post them up because i can't seem to find any!!!

--z3254433 05:43, 9 September 2010 (UTC)

ok I have chuck in the spina bifida and anencephaly detection in there, I would have the Down Syndrome detection up soon as well. I will help find pictures of thoses disorders as well and have them up as soon as possible. (Note to self: remember to edit the AFP in pregnancy so it doesn't overlap with the disorder section)


--3216889 13:52, 12 September 2010 (UTC)----

just upload the picture you emailed to us :) it should be fine hehe anyway, just added extra parts :) --3186755 16:00, 12 September 2010 (UTC)

hey guys, did 3290040 respond to any of the emails you sent? --3186755 11:56, 13 September 2010 (UTC)

hey, i got no response, Q) why won't these pics upload on our page???



--z3254433 11:18, 14 September 2010 (UTC)

ummm not sure? maybe try and just upload onto the main page and see if its like that i guess :S the other pictures seem to work fine on the main page --3186755 15:50, 14 September 2010 (UTC)

so i redid all the references since no one knew how to edit them properly. However, i couldnt really find the proper references for the following:

Green 1995. See n. 6, p. 232

Iles and Gath 1993. See n. 30, p. 411

so i'll leave it here in discussion to be cleared up and take it off the main page hehe

--3186755 13:51, 15 September 2010 (UTC)