Talk:2010 Group Project 3

Co-ordinator Comments

--This is an area for members of the group to communicate online and to place links and information relevant to the project. Do not forget to sign your additions and always add the newer material to the top of this page.

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--z3292208 06:27, 15 August 2010 (UTC)

Here are some links to start off:

Historic background: http://www.ob-ultrasound.net/amniocentesis.html

Procedure: http://www.mjbovo.com/Pregnancy/PregAmnio.htm

Risks: http://www.wisegeek.com/what-are-the-risks-of-amniocentesis.htm

Main risks include 1) Miscarriage or pre-term labor, statistics have reduced in recent years. 2) Infection through the needle to the mother. 3) If the placenta is accidentally pricked mixing of neonatal blood and mothers blood may occur causing a condition where the mothers immune system attacks the fetus as a foreign body. This occurs due to a difference in blood type, one being Rh-positive, one being Rh-negative, although this can be tested before the procedure (checking the parents genotype) and extra care can be taken. 4) Harm to the baby from the needle, but ultrasound reduces this significantly.

Risk of miscarriage is less than 1% according to http://www.genetics.com.au/pdf/factsheets/fs17c.pdf.

--z3292208 08:46, 12 August 2010 (UTC)

Hey guys so I've rethought the structure a bit and added some detail that we should look into:

1. Historic background:

- When was it first used?

- How was the technique developed?

- The key scientists involved.

- Trends in its use.

2. Procedure

- Who is eligible for the procedure?

- Are there women/couples more suited to the test? (e.g family history in genetic disorders or previous birth with a genetic defect)

- When is the test taken during pregnancy?

- How is the procedure performed? Method, steps involved.

3. Risks

- Side effects, complications, short and long term (short term like infections, long term possible effects to the baby, abortion or induced early birth?)

- Could do an advantages/disadvantages table maybe?

4. Disorders detected

- What components of the amniotic fluid do they isolate and analyse, and what do they test for? (I read that there are a few hundred disorders that they can test for but the parents and doctor only choose certain ones for them to test, and also there are some main ones so maybe we'll just pick the most common ones and do those, e.g. chromosomal disorders like Down syndrome and neural tube defects like spina bifida).

5. Diagnostic accuracy

- How accurate is the testing, statistics.

6. Ethical issues

- Professional and public opinions about the test, is it a more common diagnostic technique?

7. Current research

- Is there any current research being done to improve the procedure? There may not be...

What do you guys think? If there's anything you think we should add post it up top (apparently we're supposed to post new things at the top of the page) if not then we should think how to split up the workload so we can start getting into it.

Tegan.

--z3292208 00:14, 12 August 2010 (UTC)

Areas to look into:

1. Historic Background

2. Procedure, method.

3. Complications

4. Benefits, what disorders can be detected and prevented, option of abortion.

5. Current research on the procedure

Anything else you guys can think of to include?

--z3254753 00:33, 12 August 2010 (UTC)

nice work! i think '4.Benefits, what disorders can be detected and prevented, option of abortion' would be a big one, maybe whoever takes that one just has that point, and the other two ppl take two points each? what do you guys think?

hi everybody!

--Mark Hill 22:56, 11 August 2010 (UTC) Well group 3 where is your work that should have been done before this week's Lab?