Talk:2009 Group Project 2

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Revision as of 23:57, 26 September 2009 by Z3254857 (talk | contribs)

--Vishnnu Shanmugam 12:13, 26 September 2009 (EST) Great work fly group. Your assignment looks visually appealing and the information presented is well summarized (still amazed that a fly can fully develop in 22 hours). A real plus point in your assignment is how you've used RELEVANT images to support the text. Now let's get to what matters. Ways to improve the assignment:

- With the timeline of Drosophila Development, try to add keys or labels to the "timetable of embryogenesis" image to distinguish the different developing structures. I't a bit hard to see what the green, red and yellow structures in the image represent.

- Under "history of embryological model use" and "genetics" you might be able to mension Gregor Mendel, his work with flies and the contribution he made to the genetics of all organisms as well as the fly.

- The genetics section needs more information maybe the inclusion of how phenotype changes can be achieved from Monohybrid cross of flies with dominant and recessive alleles. Find out more my google searching "Mendelian inheritance". This can then flow to improve the current research section on "The use of Drosophila as a model for the development of human traits".

- The current reaserch section needs some work on it. The inclusion of visual aid to support the text should help. Investigate on dominant/recessive genetic trees and how they are used in Drosophila to model inherited diseases.

- The assignment needs to be properly referenced as there is no references made in the actual text. see www.lc.unsw.edu.au/onlib/ref_apa.html for help with APA referencing.

- A Glossary would also complement the text.

Overall great job.....some additions will make it excellent!


--Elide Newton 14:26, 26 September 2009 (EST) HELLO GROUP 2: Well concrats on producing a really great assignment! I'm impressed with the staging sections and how well the visual content represents the written. Well my one comment of improvement would have to be on equal content for each section. I feel the last 2 sections ( genetics and current research) are lacking in info. I understand genetics might be difficult to get informations. For the current research section try Pubmed and type in the fly, these articles will be cutting edge. Also if you could include How they are used in current research.. eg are their genes manipulate, cross bred, transgenic etc. ie the process of how they are used ? I really hope this helps!


--Jin Lee 16:56, 26 September 2009 (EST)congratulation group 2. Well done! it's a great assignment! Here is my comments: History section needs to be referenced properly and may be some more images and relevant links as well. Information about genetics and current research are little lacking..try to add some links. I am very impressed with the images in the staging section and the way it links to more information. the assignment needs to be looked after the reference part.


--Begum Sonmez 22:37, 26 September 2009 (EST) Hello Group 2, Congratulations on your page. I found that your page was interesting, and easy to read. No overload. Just wanted to say a few things about the History section:

  • The overuse of the word In is unnecessary, and repetitive. A possible alternative would be to replce them with the DATE or the Researchers as sub-headings.
  • When mentioning a researcher for the first time, refer to them with their full name whenever possible. This is relevant to the viewer as he or she may make use of the full name (they may want to 'google' the researcher for example).
  • I found that some of the findings were expressed generally rather than making direct reference to the Drosophilia embryo. For example, instead of stating that Morgan won a nobel prize 'for his discovery that genes are carried on chromosomes and are the mechanical basis of hereditary', a brief explanation of how Morgan used your chosen animals embryo would be useful. I hope I am making sense.
  • A direct link to the researcher's published article would be helpful whenever possible. This allows for quick access for an interested viewer.

For the Genetics section:

  • The Genetics section was interesting, however considering the great importance of genetics, more information would be more informative. It can be improved with information on transgenic Drosophilia, or drosophilia stem cells.
  • After mentioning the simplicity of it's genome, you have outlined the use of the embryo to '...trial new gene expressions in its genome.' This is not a major concern for me, though the inclusion of an example would be more informative.

The current research section was very clear, relevant to the topic, interesting, and informative.

The 'Helpful Links' were relevant to the topic, and they were 'Helpful'. In particular, the FlyBase.

Last of all, a direct link to a video showing the development of the musculature or the gut would be interesting to see. But I find that it isn't crucial to have when the information is structured very well. This is more so, for the reason of the presence of a different medium.

Overall, I found that the structure of each section was clear and easy to read and understand. The sentences in each paragraph were flowing very well (in particular, the introduction). The content of the page was highly relevant. Great job Group 2, I'm impressed.






--Mark Hill 01:42, 8 September 2009 (EST) New comments should go to the top of the page, much easier to read. Like the Rabbit group, your project lacks visual interest. Where are the images of development? You want people to find this project interesting. There is more to researching this topic than simply what you can find on Wikipedia.

Hallo group 2

Being that I have no idea who you all are, let me introduce myself, I am Mitchell.

As for our little topic, what does everyone think about what we should choose?

Personally, I think Guinea Pig and Rat will obviously have the most information available, but obviously everyone is thinking the same, so it might not be available. The others should be interesting, but it would be challenging to find much information on them.

Thoughts??


carly: http://www.google.com.au/search?q=History+of+Drosophila+Embryological+Model+Use&hl=en&client=firefox-a&channel=s&rls=org.mozilla:en-US:official&hs=WT4&sa=G&tbo=p&tbs=tl:1&num=20&ei=nUefSvP1JJf6kAXBht3PDw&oi=timeline_navigation_bar&ct=timeline-navbar&cd=1


Helpful links: http://embryology.med.unsw.edu.au/Otheremb/Fly.htm

http://embryology.med.unsw.edu.au/Movies/fly.htm

http://people.ucalgary.ca/~browder/virtualembryo/flies.html

http://www.medicalnewstoday.com/articles/131669.php

http://biology.kenyon.edu/courses/biol114/Chap13/Chapter_13A.html

http://www.sdbonline.org/fly/atlas/00atlas.htm

http://www.sdbonline.org/fly/aimain/1aahome.htm

http://www.sdbonline.org/fly/aimain/2stages.htm

http://www.sciencemag.org/cgi/content/abstract/287/5461/2185

I have also found that the 'Biology' 3rd edition by Knox textbook is fairly amazing, at least for the stages. Could be good for some inspiration??


Juls -  Timeline of Development - how long
    Mitchell - Staging - are there species specific staging, what occurs when
      Carly  - History of Model Use - when was it first used, what embryology research
        Tom  - Genetics - chromosome number, sequencing

Group Effort - Current Embryology Research - research papers and findings


Tom's notes:

http://www.yale.edu/ynhti/curriculum/units/1996/5/96.05.01.x.html

http://www.accessexcellence.org/AE/AEPC/WWC/1994/genentics.php

http://books.google.com.au/books?id=CgtIr1V0zxAC&printsec=frontcover&dq=drosophila+genetics&source=gbs_similarbooks_r&cad=3#v=onepage&q=&f=false

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=Retrieve&list_uids=29999

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genome&Cmd=ShowDetailView&TermToSearch=10015

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2147996&tool=pmcentrez

http://en.wikipedia.org/wiki/Drosophila_melanogaster

http://www.fruitfly.org/about/pubs/rubin96.html

Fly pushing: the theory and practice of Drosophila genetics, Part 7 By Ralph J. Greenspan

http://bfgp.oxfordjournals.org/cgi/reprint/2/2/128.pdf

Some info:

The Drosophila melanogaster fly has four pairs of chromosomes: the X/Y sex cells and the autosomes 2, 3 and 4. The fourth chromosome is so small that it is usually overlooked. The comparison of the insignificant 4th chromosome to the other three pairs are shown in the image to the right.

The size of the Drosophila genome is about 165 million pairs and estimated to contain about 14000 genes. In comparison, humans have 3.4 billion base pairs with about 22500 gene sequences and yeast has about 5800 genes in 13.5 million base pairs. More than 60% of the genome appears to be functional non-protein-coding DNA involved in gene expression control.

Also a good link to a variety of info: http://ceolas.org/VL/fly/index.html



For Carly http://www.ncbi.nlm.nih.gov/pubmed/10731135?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=4&log$=relatedarticles&logdbfrom=pubmed




Current medical research

Parkinson's and drosophila http://www.ncbi.nlm.nih.gov/pubmed/19638420?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Evolution of visual systems http://www.ncbi.nlm.nih.gov/pubmed/19467226?ordinalpos=23&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Alzheimers http://www.ncbi.nlm.nih.gov/pubmed/17046662

Of Flies and Man: Drosophila as a Model for Human Complex Traits Trudy F. C. Mackay and Robert R. H. Anholt http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.genom.7.080505.115758 PMID: 16756480


possible pictures http://en.wikipedia.org/wiki/File:EyeColors.jpg

http://en.wikipedia.org/wiki/File:Drosophila.jpg

http://commons.wikimedia.org/wiki/File:Drosophila_melanogaster_-_side_(aka).jpg



Hey guys, Everything you have needs to be on the page by the end of session break because we need to focus on presentation and current research in the last two weeks.


tom: image....... http://commons.wikimedia.org/wiki/File:Sexlinked_inheritance_white.jpg http://commons.wikimedia.org/wiki/File:Drosophila_chromosomes.png


carly image

http://commons.wikimedia.org/wiki/File:Thomas_Hunt_Morgan.jpg