Talk:2009 Group Project 2: Difference between revisions

Revision as of 12:11, 26 September 2009

Great work fly group. Your assignment looks visually appealing and the information presented is well summarized (still amazed that a fly can fully develop in 22 hours). A real plus point in your assignment is how you've used RELEVANT images to support the text. Now let's get to what matters:--Vishnnu Shanmugam 12:11, 26 September 2009 (EST)

Ways to improve the assignment: - With the timeline of Drosophila Development, try to add keys or labels to the "timetable of embryogenesis" image to distinguish the different developing structures. I't a bit hard to see what the green, red and yellow structures in the image represent.

- Under "history of embryological model use" and "genetics" you might be able to mension Gregor Mendel, his work with flies and the contribution he made to the genetics of all organisms as well as the fly.

- The genetics section needs more information maybe the inclusion of how phenotype changes can be achieved from Monohybrid cross of flies with dominant and recessive alleles. Find out more my google searching "Mendelian inheritance". This can then flow to improve the current research section on "The use of Drosophila as a model for the development of human traits".

- The current reaserch section needs some work on it. The inclusion of visual aid to support the text should help. Investigate on dominant/recessive genetic trees and how they are used in Drosophila to model inherited diseases.

- The assignment needs to be properly referenced as there is no references made in the actual text. see www.lc.unsw.edu.au/onlib/ref_apa.html for help with APA referencing.

- A Glossary would also complement the text.

Overall great job.....some additions will make it brillant!

--Mark Hill 01:42, 8 September 2009 (EST) New comments should go to the top of the page, much easier to read. Like the Rabbit group, your project lacks visual interest. Where are the images of development? You want people to find this project interesting. There is more to researching this topic than simply what you can find on Wikipedia.

Hallo group 2

Being that I have no idea who you all are, let me introduce myself, I am Mitchell.

As for our little topic, what does everyone think about what we should choose?

Personally, I think Guinea Pig and Rat will obviously have the most information available, but obviously everyone is thinking the same, so it might not be available. The others should be interesting, but it would be challenging to find much information on them.

Thoughts??

carly: http://www.google.com.au/search?q=History+of+Drosophila+Embryological+Model+Use&hl=en&client=firefox-a&channel=s&rls=org.mozilla:en-US:official&hs=WT4&sa=G&tbo=p&tbs=tl:1&num=20&ei=nUefSvP1JJf6kAXBht3PDw&oi=timeline_navigation_bar&ct=timeline-navbar&cd=1

Helpful links: http://embryology.med.unsw.edu.au/Otheremb/Fly.htm

http://embryology.med.unsw.edu.au/Movies/fly.htm

http://people.ucalgary.ca/~browder/virtualembryo/flies.html

http://www.medicalnewstoday.com/articles/131669.php

http://biology.kenyon.edu/courses/biol114/Chap13/Chapter_13A.html

http://www.sdbonline.org/fly/atlas/00atlas.htm

http://www.sdbonline.org/fly/aimain/1aahome.htm

http://www.sdbonline.org/fly/aimain/2stages.htm

http://www.sciencemag.org/cgi/content/abstract/287/5461/2185

I have also found that the 'Biology' 3rd edition by Knox textbook is fairly amazing, at least for the stages. Could be good for some inspiration??

Juls -  Timeline of Development - how long

    Mitchell - Staging - are there species specific staging, what occurs when

      Carly  - History of Model Use - when was it first used, what embryology research

        Tom  - Genetics - chromosome number, sequencing

Group Effort - Current Embryology Research - research papers and findings

Tom's notes:

http://www.yale.edu/ynhti/curriculum/units/1996/5/96.05.01.x.html

http://www.accessexcellence.org/AE/AEPC/WWC/1994/genentics.php

http://books.google.com.au/books?id=CgtIr1V0zxAC&printsec=frontcover&dq=drosophila+genetics&source=gbs_similarbooks_r&cad=3#v=onepage&q=&f=false

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=Retrieve&list_uids=29999

http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genome&Cmd=ShowDetailView&TermToSearch=10015

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2147996&tool=pmcentrez

http://en.wikipedia.org/wiki/Drosophila_melanogaster

http://www.fruitfly.org/about/pubs/rubin96.html

Fly pushing: the theory and practice of Drosophila genetics, Part 7 By Ralph J. Greenspan

http://bfgp.oxfordjournals.org/cgi/reprint/2/2/128.pdf

Some info:

The Drosophila melanogaster fly has four pairs of chromosomes: the X/Y sex cells and the autosomes 2, 3 and 4. The fourth chromosome is so small that it is usually overlooked. The comparison of the insignificant 4th chromosome to the other three pairs are shown in the image to the right.

The size of the Drosophila genome is about 165 million pairs and estimated to contain about 14000 genes. In comparison, humans have 3.4 billion base pairs with about 22500 gene sequences and yeast has about 5800 genes in 13.5 million base pairs. More than 60% of the genome appears to be functional non-protein-coding DNA involved in gene expression control.

Also a good link to a variety of info: http://ceolas.org/VL/fly/index.html

For Carly http://www.ncbi.nlm.nih.gov/pubmed/10731135?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=4&log$=relatedarticles&logdbfrom=pubmed

Current medical research

Parkinson's and drosophila http://www.ncbi.nlm.nih.gov/pubmed/19638420?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Evolution of visual systems http://www.ncbi.nlm.nih.gov/pubmed/19467226?ordinalpos=23&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Alzheimers http://www.ncbi.nlm.nih.gov/pubmed/17046662

Of Flies and Man: Drosophila as a Model for Human Complex Traits Trudy F. C. Mackay and Robert R. H. Anholt http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.genom.7.080505.115758 PMID: 16756480

possible pictures http://en.wikipedia.org/wiki/File:EyeColors.jpg

http://en.wikipedia.org/wiki/File:Drosophila.jpg

http://commons.wikimedia.org/wiki/File:Drosophila_melanogaster_-_side_(aka).jpg

Hey guys, Everything you have needs to be on the page by the end of session break because we need to focus on presentation and current research in the last two weeks.

tom: image....... http://commons.wikimedia.org/wiki/File:Sexlinked_inheritance_white.jpg http://commons.wikimedia.org/wiki/File:Drosophila_chromosomes.png

carly image

http://commons.wikimedia.org/wiki/File:Thomas_Hunt_Morgan.jpg

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+Great work fly group. Your assignment looks visually appealing and the information presented is well summarized (still amazed that a fly can fully develop in 22 hours). A real plus point in your assignment is how you've used RELEVANT images to support the text. Now let's get to what matters:--[[User:Z3187802|Vishnnu Shanmugam]] 12:11, 26 September 2009 (EST)
+Ways to improve the assignment:
+- With the timeline of Drosophila Development, try to add keys or labels to the "timetable of embryogenesis" image to distinguish the different developing structures. I't a bit hard to see what the green, red and yellow structures in the image represent.
+- Under "history of embryological model use" and "genetics" you might be able to mension Gregor Mendel, his work with flies and the contribution he made to the genetics of all organisms as well as the fly.
+- The genetics section needs more information maybe the inclusion of how phenotype changes can be achieved from Monohybrid cross of flies with dominant and recessive alleles. Find out more my google searching  "Mendelian inheritance". This can then flow to improve the current research section on "The use of Drosophila as a model for the development of human traits".
+- The current reaserch section needs some work on it. The inclusion of visual aid to support the text should help. Investigate on dominant/recessive genetic trees and how they are used in Drosophila to model inherited diseases.
+- The assignment needs to be properly referenced as there is no references made in the actual text. see www.lc.unsw.edu.au/onlib/ref_apa.html for help with APA referencing.
+- A Glossary would also complement the text.
+Overall great job.....some additions will make it brillant!
 --[[User:S8600021|Mark Hill]] 01:42, 8 September 2009 (EST) New comments should go to the top of the page, much easier to read. Like the Rabbit group, your project lacks visual interest. Where are the images of development? You want people to find this project interesting. There is more to researching this topic than simply what you can find on Wikipedia.