Sheep Development: Difference between revisions

From Embryology
mNo edit summary
mNo edit summary
Line 15: Line 15:
|}
|}
{| class="wikitable mw-collapsible mw-collapsed"
{| class="wikitable mw-collapsible mw-collapsed"
! More recent papers
! More recent papers  
|-
|-
| [[File:Mark_Hill.jpg|90px|left]] {{Most_Recent_Refs}}
| [[File:Mark_Hill.jpg|90px|left]] {{Most_Recent_Refs}}

Revision as of 17:46, 1 August 2016

Embryology - 28 Mar 2024    Facebook link Pinterest link Twitter link  Expand to Translate  
Google Translate - select your language from the list shown below (this will open a new external page)

العربية | català | 中文 | 中國傳統的 | français | Deutsche | עִברִית | हिंदी | bahasa Indonesia | italiano | 日本語 | 한국어 | မြန်မာ | Pilipino | Polskie | português | ਪੰਜਾਬੀ ਦੇ | Română | русский | Español | Swahili | Svensk | ไทย | Türkçe | اردو | ייִדיש | Tiếng Việt    These external translations are automated and may not be accurate. (More? About Translations)

Introduction

Sheep with lamb with second (twin) lamb being born.

The domestic sheep (Ovis aries) has been used as a mammalian model of development.

  • term gestational days = 145 days

Some Recent Findings

  • Development of morulae from the oocytes of cultured sheep preantral follicles[1] "Sheep preantral follicles (PFs) measuring 250-400 microm in diameter were cultured for six days in serum-free media supplemented differently with growth factors and hormones. ...In combination with T4 and FSH, IGF-I+GH supported the best development of the PFs. Culture of PFs in micro drops or agar gel supported similarly high development. In vitro fertilization of the oocytes from the cultured sheep PFs resulted in the embryos developing to the morula stage for the first time."
  • Viral particles of endogenous betaretroviruses are released in the sheep uterus and infect the conceptus trophectoderm in a transspecies embryo transfer model[2]
More recent papers  
Mark Hill.jpg
PubMed logo.gif

This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.

  • This search now requires a manual link as the original PubMed extension has been disabled.
  • The displayed list of references do not reflect any editorial selection of material based on content or relevance.
  • References also appear on this list based upon the date of the actual page viewing.


References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability.

More? References | Discussion Page | Journal Searches | 2019 References | 2020 References

Search term: Sheep Embryology

<pubmed limit=5>Sheep Embryology</pubmed>

Development Overview

Sheep follicle in vitro[3]
  • day 4 - embryo enters the uterus at the morula stage of development
  • day 6 - develops into a blastocyst
  • day 8 - blastocyst hatches from zona pellucida
  • day 11-16 - elongates to a filamentous form
  • day 14 - 16 - binucleate cells begin to differentiate in the trophoblast
  • day 16 - adplantation

See also Implantation mechanisms: insights from the sheep[4]

Dolly

Dolly the sheep (5 July 1996 – 14 February 2003)

A female domestic sheep remarkable in being the first mammal to be cloned from an adult somatic cell, using the process of nuclear transfer.[5]

Cloned by Ian Wilmut, Keith Campbell and colleagues at the Roslin Institute near Edinburgh in Scotland, born on 5 July 1996 and she lived until the age of six (5 July 1996 – 14 February 2003). The cell used as the donor for the cloning of Dolly was taken from a mammary gland, and the production of a healthy clone therefore proved that a cell taken from a specific part of the body could recreate a whole individual. As Dolly was cloned from part of a mammary gland, she was named after the famously curvaceous country western singer Dolly Parton.


Links: Roslin Institute, Edinburgh | Science Museum - Dolly the sheep, 1996-2003


Oocyte Development

Sheep follicle gene expression 01.jpg

Sheep follicle gene expression[6]
  • red - genes expressed in granulose cells.
  • blue - genes expressed in oocytes.
  • black - genes expressed both in oocytes and granulosa cells.


Sheep Oocyte Distribution of Telomerase reverse transcriptase

The following oocyte images are from a recent study of sheep in vitro follicle development.[7]

Sheep oocyte 01.jpg Sheep oocyte 02.jpg
preantral early antral
Sheep oocyte 03.jpg Sheep oocyte 04.jpg
early antral preovulatory follicle
  • TERT - Red (Cy3-conjugated secondary antibody) (telomerase reverse transcriptase, TERT)
  • DNA - Green (SYBR Green 14/I)


Sheep Oocyte TERT: preantral | early antral | early antral | preovulatory follicle | Oocyte Development | Sheep Development

Respiratory

Phases of fetal lung development:[8]

  1. embryonic - 0 to 40 days.
  2. pseudoglandular - 40 to 80 days.
  3. canalicular - 80 to 120 days.
  4. saccular - 120 to term 148 days gestation.


Links: Respiratory Development

Immune

Lymphocytes development has been characterised by an immunohistology study of T lymphocytes in the sheep fetal spleen.[9]

  • 43-44 days of gestation, SBU-T1- and SBU-T8-positive lymphocytes were present in low numbers.
  • 45-50 days of gestation Surface immunoglobulin (sIg) was first detected on fetal spleen cells
  • 50-55 days of gestation SBU-T4, 20.96-, 25.69-, 38.38-, or 46.66-positive lymphocytes present.
  • 57 days of gestation SBU-T19 lymphocytes appeared.


Links: Immune Development

References

  1. <pubmed>20615540</pubmed>
  2. <pubmed>20610723</pubmed>
  3. <pubmed>22132111</pubmed>| PLoS One.
  4. <pubmed>15579583</pubmed>
  5. <pubmed>9039911</pubmed>
  6. <pubmed>26540452</pubmed>| PLoS One.
  7. <pubmed>22132111</pubmed>| PLoS One.
  8. <pubmed>15774522</pubmed>| PMC1464504
  9. <pubmed>3308689</pubmed>


Reviews

<pubmed>19726075</pubmed> <pubmed>16008756</pubmed>

Articles

<pubmed>19909921</pubmed> <pubmed>15047940</pubmed>| Reproduction

Search PubMed

Search Pubmed: sheep development | ovine development | ovine embryo development

External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.




Animal Development: axolotl | bat | cat | chicken | cow | dog | dolphin | echidna | fly | frog | goat | grasshopper | guinea pig | hamster | horse | kangaroo | koala | lizard | medaka | mouse | opossum | pig | platypus | rabbit | rat | salamander | sea squirt | sea urchin | sheep | worm | zebrafish | life cycles | development timetable | development models | K12
Historic Embryology  
1897 Pig | 1900 Chicken | 1901 Lungfish | 1904 Sand Lizard | 1905 Rabbit | 1906 Deer | 1907 Tarsiers | 1908 Human | 1909 Northern Lapwing | 1909 South American and African Lungfish | 1910 Salamander | 1951 Frog | Embryology History | Historic Disclaimer


Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link



Cite this page: Hill, M.A. (2024, March 28) Embryology Sheep Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Sheep_Development

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G