SH Practical - Respiratory: Difference between revisions
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:'''Virtual Slides:''' [http://vslides.unsw.edu.au/VirtualSlideV2.nsf/id/F51ED7 Respiratory Histology] | :'''Virtual Slides:''' [http://vslides.unsw.edu.au/VirtualSlideV2.nsf/id/F51ED7 Respiratory Histology] | ||
{{SH2011}} | {{SH2011}} | ||
==Upper Respiratory Tract - Nasal Cavity== | |||
===Respiratory=== | |||
{| | |||
| [[File:Respiratory histology 12.jpg|400px]] | |||
| [[File:Respiratory histology 11.jpg|400px]] | |||
|- | |||
| Nasal respiratory epithelium (inferior concha) | |||
| Nasal respiratory epithelium (detail) | |||
|} | |||
{{Nasal respiratory links}} | |||
===Olfactory=== | |||
Nasal cavity olfactory epithelium cells | |||
# Olfactory cells | |||
# Sustentacular cells - located mainly in the superficial cell layer of the epithelium (difficult to distinguish from olfactory cells). | |||
# Basal cells - identified by their location. | |||
{| | |||
| width=300px| '''Epithelium''' | |||
* Cilia are not visible | |||
* goblet cells are absent from the olfactory epithelium. | |||
| width=300px| '''Lamina Propria''' | |||
* olfactory axon bundles (lightly stained, rounded areas) connected to olfactory cells. | |||
* Bowman's glands - (small mucous glands, olfactory glands) function to moisturise the epithelium. | |||
|} | |||
{| | |||
|- | |||
| [[File:Respiratory histology 13.jpg|400px]] | |||
| [[File:Respiratory histology 14.jpg|400px]] | |||
|- | |||
| Nasal cavity olfactory | |||
| Nasal cavity olfactory (detail) | |||
|} | |||
{{Nasal olfactory links}} | |||
==Trachea== | |||
[[File:Hyaline_cartilage_03.jpg|thumb|trachea histology]] | |||
'''Mucosa''' - formed by epithelium and underlying lamina propria. | |||
* respiratory epithelium - (pseudostratified columnar and ciliated) ciliated cells, goblet cells, brush cells, endocrine cells, surfactant-producing cells (Clara cells), serous cells, basal cells, basement membrane. | |||
* lamina propria - loose connective tissue, many elastic fibres. | |||
* elastic lamina - forming the border between the mucosa and submucosa is not visible in H&E stained slides. | |||
'''Submucosa''' - connective tissue and submucosal glands. | |||
===Submucosal Glands=== | |||
(muco-serous) serous (dark) and mucous (light) parts have different staining appearance. | |||
* Mucous secretions - "slimy" (high viscosity) mucous acini cells appear "foamy" or "frothy" and poorly stained (light). nuclei dark and smaller than serous. | |||
* Serous secretions - "watery" (low viscosity) serous acini cell apical cytoplasm is usually well-stained (dark). nuclei round to ovoid located in cell basal cytoplasm. | |||
===Cartilage=== | |||
* perichondrium - surface of cartilage. | |||
* tracheal cartilage - hyaline cartilage, 16 to 20 C-shaped cartilages. | |||
* trachealis muscle - (smooth muscle) Not visible in this section, together with connective tissue fibres, join ends of the cartilages together. | |||
===Hyaline Cartilage Development=== | |||
* forms from mesenchymal cells. | |||
* precursor cells become rounded and form densely packed cellular masses, chondrification centres. | |||
* chondroblasts - (cartilage-forming cells) begin secreting the extracellular matrix components of cartilage. | |||
** extracellular matrix - ground substance (hyaluronan, chondroitin sulfates and keratan sulfate) and tropocollagen (polymerises into fine collagen fibres, not visible). | |||
{{Trachea histology links}} | |||
[[File:Hyaline_cartilage_03.jpg|400px]] [[File:Hyaline_cartilage_04.jpg|400px]] | |||
[[File:Respiratory histology 05.jpg|400px]] [[File:Respiratory histology 06.jpg|400px]] | |||
{{Trachea histology links}} | |||
==Bronchiole== | |||
[[File:Respiratory_histology_01.jpg|400px]] [[File:Respiratory_histology_09.jpg|400px]] | |||
==Alveolar Ducts and Alveoli== | |||
{| | |||
|- | |||
| valign=top width=350px|'''Alveolar type I cells''' | |||
* small alveolar cells or type I pneumocytes | |||
* are extremely flattened (the cell may be as thin as 0.05 µm) | |||
* form the bulk (95%) of the surface of the alveolar walls. | |||
* The shape of the cells is very complex, and they may actually form part of the epithelium on both faces of the alveolar wall. | |||
| valign=top width=350px|'''Alveolar type II cells''' | |||
* large alveolar cells or type II pneumocytes | |||
* about as many type II cells as type I cells (cell shape accounts for small contribution to alveolar area). | |||
* irregularly (sometimes cuboidal) shaped. | |||
* form small bulges on the alveolar walls. | |||
* contain are large number of granules called cytosomes (or multilamellar bodies) | |||
** consist of precursors to pulmonary surfactant (mixture of phospholipids that keep surface tension in the alveoli low). | |||
|} | |||
[[File:Respiratory_histology_08.jpg|400px]] [[File:Respiratory_histology_07.jpg|400px]] | |||
{| | |||
| [[File:Respiratory_histology_02.jpg|200px]] | |||
| [[File:Respiratory_histology_03.jpg|200px]] | |||
| [[File:Respiratory histology 04.jpg|200px]] | |||
| [[File:Respiratory_histology_10.jpg|200px]] | |||
|- | |||
| Alveolar Duct | |||
| Alveoli | |||
| Alveoli Elastin | |||
| Lung Reticular Fibres | |||
|} | |||
Revision as of 09:19, 3 April 2013
Introduction
Current page provides further background information for Medicine phase 1 Society and Health Respiratory Histology Practical Virtual Slides. This page content is not part of the SH practical class.
- Virtual Slides: Respiratory Histology
- SH Links: Lymphatic Lecture | Lymphatics Practical Support | Respiratory Lecture | Respiratory Practical Support | Medicine
Upper Respiratory Tract - Nasal Cavity
Respiratory
Nasal respiratory epithelium (inferior concha) | Nasal respiratory epithelium (detail) |
Olfactory
Nasal cavity olfactory epithelium cells
- Olfactory cells
- Sustentacular cells - located mainly in the superficial cell layer of the epithelium (difficult to distinguish from olfactory cells).
- Basal cells - identified by their location.
Epithelium
|
Lamina Propria
|
Nasal cavity olfactory | Nasal cavity olfactory (detail) |
- Nasal Olfactory Histology: overview image | detail image | Smell Development | Histology | Histology Stains
Trachea
Mucosa - formed by epithelium and underlying lamina propria.
- respiratory epithelium - (pseudostratified columnar and ciliated) ciliated cells, goblet cells, brush cells, endocrine cells, surfactant-producing cells (Clara cells), serous cells, basal cells, basement membrane.
- lamina propria - loose connective tissue, many elastic fibres.
- elastic lamina - forming the border between the mucosa and submucosa is not visible in H&E stained slides.
Submucosa - connective tissue and submucosal glands.
Submucosal Glands
(muco-serous) serous (dark) and mucous (light) parts have different staining appearance.
- Mucous secretions - "slimy" (high viscosity) mucous acini cells appear "foamy" or "frothy" and poorly stained (light). nuclei dark and smaller than serous.
- Serous secretions - "watery" (low viscosity) serous acini cell apical cytoplasm is usually well-stained (dark). nuclei round to ovoid located in cell basal cytoplasm.
Cartilage
- perichondrium - surface of cartilage.
- tracheal cartilage - hyaline cartilage, 16 to 20 C-shaped cartilages.
- trachealis muscle - (smooth muscle) Not visible in this section, together with connective tissue fibres, join ends of the cartilages together.
Hyaline Cartilage Development
- forms from mesenchymal cells.
- precursor cells become rounded and form densely packed cellular masses, chondrification centres.
- chondroblasts - (cartilage-forming cells) begin secreting the extracellular matrix components of cartilage.
- extracellular matrix - ground substance (hyaluronan, chondroitin sulfates and keratan sulfate) and tropocollagen (polymerises into fine collagen fibres, not visible).
- Trachea Histology Links: Overview HE | Overview VG | Detail 1 HE Detail 2 HE | Respiratory Histology | Histology Stains | Histology
- Trachea Histology Links: Overview HE | Overview VG | Detail 1 HE Detail 2 HE | Respiratory Histology | Histology Stains | Histology
Bronchiole
Alveolar Ducts and Alveoli
Alveolar type I cells
|
Alveolar type II cells
|
Alveolar Duct | Alveoli | Alveoli Elastin | Lung Reticular Fibres |
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 24) Embryology SH Practical - Respiratory. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/SH_Practical_-_Respiratory
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G