Rabbit Development: Difference between revisions
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==Rabbit Placentation== | ==Rabbit Placentation== | ||
Rabbit implantation and placentation is a centric (or fusion) type, where the blastocyst adheres only to the epithelial cells (apical region) by trophectoderm forming projections.<ref>Animal models of implantation. Lee KY, DeMayo FJ. Reproduction. 2004 Dec;128(6):679-95. Review. [http://www.ncbi.nlm.nih.gov/pubmed/15579585 PMID: 15579585]</ref> | Rabbit implantation and placentation is a centric (or fusion) type, where the blastocyst adheres only to the epithelial cells (apical region) by trophectoderm forming projections.<ref>Animal models of implantation. Lee KY, DeMayo FJ. Reproduction. 2004 Dec;128(6):679-95. Review. [http://www.ncbi.nlm.nih.gov/pubmed/15579585 PMID: 15579585]</ref> | ||
==Neural Development== | ==Neural Development== |
Revision as of 22:23, 22 April 2010
Introduction
As an embryological tool, the rabbit (Taxon- Oryctolagus cuniculus) along with human was a species which show birth defects with thalidomide (teratogenic effects not detected with prior testing on other species). These animals are herbivores with a very high breeding rate and number of offspring produced.
Links: 2009 ANAT2341 Group Project - Rabbit | Original Rabbit page
Taxon
Oryctolagus cuniculus
Taxonomy Id: 9986 Rank: species
Genetic code: Translation table 1 (Standard) Mitochondrial genetic code: Translation table 2 Other names: New Zealand rabbit[includes], rabbits[common name], European rabbit[common name], Japanese white rabbit[common name], domestic rabbit[common name], rabbit[common name], Lepus cuniculus[misnomer]
Lineage( abbreviated ): Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria; Lagomorpha; Leporidae; Oryctolagus
Rabbit Cycle
Rabbit Placentation
Rabbit implantation and placentation is a centric (or fusion) type, where the blastocyst adheres only to the epithelial cells (apical region) by trophectoderm forming projections.[1]
Neural Development
The data below is summarised from an excellent study of early neural development in the rabbit.[2] The same authors have studied neural development in the pig.
- 6-8 somite stage - the flat neural plate transforms into a V-shaped neural groove (beginning at rhombo-cervical level)
- 8 and 9 somite stage - multiple closure sites occur simultaneously at three levels
- incipient pros-mesencephalic transition
- incipient mes-rhombencephalic transition
- level of the first pairs of somites
results in four transient neuropores
anterior neuropore
- 9-11 somite stages - anterior and rhombencephalic neuropores close
- mesencephalic neuropore is very briefly present
posterior neuropore
- largest and remains open longest
- 9-10 somite stages - tapered (cranial) portion closes fast within
- wide (caudal) portion closes up to a narrow slit
- further closure slows
- 22 somite stage - full closure occurs
compared with chick and mouse - sequence of multiple site closure resembles that of the mouse embryo, but other important aspects of neurulation resemble those of the chick embryo. In contrast to mouse and chick, no time lag between closure at the three closure sites in the rabbit was seen
Rabbit Immune Development
Rabbits generate their antibody repertoire in three stages.[3]
- Neonatal repertoire is generated by B lymphopoiesis in fetal liver and bone marrow (limited by preferential V(H) gene segment usage).
- Between 4 and 8 weeks after birth gut-associated lymphoid tissue (GALT) a complex primary antibody repertoire.
- The primary antibody repertoire is subsequently modified during antigen-dependent immune responses (the secondary repertoire).
Rabbits uniquely develop a primary antibody repertoire through somatic diversification of Ig genes (dependent on intestinal microbial flora).
References
- ↑ Animal models of implantation. Lee KY, DeMayo FJ. Reproduction. 2004 Dec;128(6):679-95. Review. PMID: 15579585
- ↑ Neurulation in the rabbit embryo. Peeters MC, Viebahn C, Hekking JW, van Straaten HW. Anat Embryol (Berl). 1998 Mar;197(3):167-75. PMID: 9543335
- ↑ Development of the antibody repertoire in rabbit: gut-associated lymphoid tissue, microbes, and selection. Lanning D, Zhu X, Zhai SK, Knight KL. Immunol Rev. 2000 Jun;175:214-28. Review. PMID: 10933605
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- rabbit development - All (26270) Review (1568) Free Full Text (5693)
- rabbit embryo - All (11734) Review (744) Free Full Text (2500)
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Cite this page: Hill, M.A. (2024, April 19) Embryology Rabbit Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Rabbit_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G