Quicktime Movie - Blastocyst Development
Human Blastocyst (day 3 to 6)
Movie shows in vitro development of a human morula stage to blastocyst stage. The movie covers the period of the first week (day 3 and day 6) post-fertilization and finishes with the blastocyst "hatching out" of the protective zone pellucida, ready to begin implantation in the second week.
00:18 day 4 - blastocoel formation, now blastocyst stage.
00:22 - inner cell mass (embryoblast)
00:29 - maximal expansion of blastocyst in ZP
00:31 - contraction
00:32 - re-expansion
00:37 day 5 - contraction
00:38 - re-expansion
00:39 - contraction (collapse)
00:40 - re-expansion (blastocoel enlargement)
00:41 - commence blastocyst hatching (1 o'clock position)
00:44 day 6 - complete hatching, blastocyst expansion (inner cell mass 2 o'clock position)
00:47 - trophoblast layer thickens
00:53 - movie finishes
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Human blastocyst development (in vitro) from day 1 to day 6.
Connie C Wong, Kevin E Loewke, Nancy L Bossert, Barry Behr, Christopher J De Jonge, Thomas M Baer, Renee A Reijo Pera Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat. Biotechnol.: 2010, 28(10);1115-21 PubMed 20890283
Reprinted by permission from Macmillan Publishers Ltd: Nat Biotechnol. (Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Wong CC, Loewke KE, Bossert NL, Behr B, De Jonge CJ, Baer TM, Pera RA. Nat Biotechnol. 2010 Oct 3. [Epub ahead of print] PMID 20890283), copyright (2010)
Licensee: Mark A Hill License Date: Oct 06, 2010 License Number: 2523401420894 Publication: Nature Biotechnology Title: Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage Type Of Use: Web Site