Quicktime Movie - Blastocyst Development

From Embryology
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Human Blastocyst (day 3 to 6)

Movie shows in vitro development of a human morula stage to blastocyst stage. The movie covers the period of the first week (day 3 and day 6) post-fertilization and finishes with the blastocyst "hatching out" of the protective zone pellucida, ready to begin implantation in the second week.


00:00 day 3 - Initially a solid mass of cells morula stage (labelled H) enclosed by the zona pellucida.

00:18 day 4 - blastocoel formation, now blastocyst stage.

00:22 - inner cell mass (embryoblast)

00:29 - maximal expansion of blastocyst in ZP

00:31 - contraction

00:32 - re-expansion

00:37 day 5 - contraction

00:38 - re-expansion

00:39 - contraction (collapse)

00:40 - re-expansion (blastocoel enlargement)

00:41 - commence blastocyst hatching (1 o'clock position)

00:44 day 6 - complete hatching, blastocyst expansion (inner cell mass 2 o'clock position)

00:47 - trophoblast layer thickens

00:53 - movie finishes


Movie Links: Flash version | Quicktime movie | Quicktime - Blastocyst Contractions | Flash - Blastocyst Contractions | Quicktime - Blastocyst Hatching | Flash - Blastocyst Hatching | Blastocyst | Quicktime Movies
Human blastocyst day 1-6.jpg

Human blastocyst development (in vitro) from day 1 to day 6.


Links: Zygote | Morula | Blastocyst | Zona pellucida | Implantation

Reference

Connie C Wong, Kevin E Loewke, Nancy L Bossert, Barry Behr, Christopher J De Jonge, Thomas M Baer, Renee A Reijo Pera Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat. Biotechnol.: 2010, 28(10);1115-21 PubMed 20890283

| Nat Biotechnol.


Copyright

Reprinted by permission from Macmillan Publishers Ltd: Nat Biotechnol. (Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Wong CC, Loewke KE, Bossert NL, Behr B, De Jonge CJ, Baer TM, Pera RA. Nat Biotechnol. 2010 Oct 3. [Epub ahead of print] PMID 20890283), copyright (2010)

Licensee: Mark A Hill License Date: Oct 06, 2010 License Number: 2523401420894 Publication: Nature Biotechnology Title: Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage Type Of Use: Web Site