Prostate Development
From Embryology
Mouse
Androgenic regulation of ventral epithelial bud number and pattern in mouse urogenital sinus. Allgeier SH, Lin TM, Moore RW, Vezina CM, Abler LL, Peterson RE. Dev Dyn. 2010 Feb;239(2):373-85. PMID: 19941349
- begins in fetal mice ductal progenitors (or buds) emerge from urogenital sinus epithelium
- prostatic buds develop in response to androgens, which activate androgen receptors in UGS mesenchyme
- two rows of 3-4 prostatic buds at birth