Placenta - Maternal Decidua
--Mark Hill 22:31, 26 May 2010 (EST) Currently Template page only.
Introduction This page gives an overview of aspects of maternal component of placental development.
In week 2, the trophoblast shell cells proliferate and form a syncitiotrophoblast and cytotrophoblast layer around he conceptus. Syncitiotrophoblast cells migrate into the uterine wall, forming maternal blood-filled spaces (lacunae).
Placentation begins once the conceptus begins to implant in the uterine wall and the placenta will have both a fetal and a maternal component.
The maternal component is formed by the decidualization of the endometrium.
The maternal uterine endometrium stromal cells (fibroblast-like) are transformed by steroid hormones (progesterone) and embryonic signals into the decidua.
The entire maternal decidua is divided into three regions: decidua basalis, decidua capsularis and decidua parietalis.
These 3 regions are named by their positional relationship to the conceptus.
Member of the a transforming growth factor beta (TGFbeta) superfamily, contributes to human endometrial stromal cells (HESC) decidualization and has been localized to decidual cells in the human endometrium. (possibly also BMP2 and TGFbeta1)
Stoikos CJ, Harrison CA, Salamonsen LA, Dimitriadis E. [See Related Articles] A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. Hum Reprod. 2008 Jun;23(6):1447-56.
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Cite this page: Hill, M.A. (2019, August 21) Embryology Placenta - Maternal Decidua. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Placenta_-_Maternal_Decidua
- © Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G