Placenta - Maternal Decidua: Difference between revisions
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--[[User:S8600021|Mark Hill]] 22:31, 26 May 2010 (EST) Currently Template page only. | --[[User:S8600021|Mark Hill]] 22:31, 26 May 2010 (EST) Currently Template page only. | ||
Introduction | |||
This page gives an overview of aspects of maternal component of placental development. | |||
In week 2, the trophoblast shell cells proliferate and form a syncitiotrophoblast and cytotrophoblast layer around he conceptus. Syncitiotrophoblast cells migrate into the uterine wall, forming maternal blood-filled spaces (lacunae). | |||
Placentation begins once the conceptus begins to implant in the uterine wall and the placenta will have both a fetal and a maternal component. | |||
The maternal component is formed by the decidualization of the endometrium. | |||
{{Template:Placenta Links}} | {{Template:Placenta Links}} | ||
==Maternal Decidua== | |||
The maternal uterine endometrium stromal cells (fibroblast-like) are transformed by steroid hormones (progesterone) and embryonic signals into the decidua. | |||
The entire maternal decidua is divided into three regions: decidua basalis, decidua capsularis and decidua parietalis. | |||
These 3 regions are named by their positional relationship to the conceptus. | |||
==Decidualization Factors== | |||
Activin A | |||
Member of the a transforming growth factor beta (TGFbeta) superfamily, contributes to human endometrial stromal cells (HESC) decidualization and has been localized to decidual cells in the human endometrium. (possibly also BMP2 and TGFbeta1) | |||
Stoikos CJ, Harrison CA, Salamonsen LA, Dimitriadis E. [See Related Articles] A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. | |||
Hum Reprod. 2008 Jun;23(6):1447-56. | |||
==References== | ==References== |
Revision as of 23:30, 26 May 2010
Introduction
--Mark Hill 22:31, 26 May 2010 (EST) Currently Template page only.
Introduction This page gives an overview of aspects of maternal component of placental development.
In week 2, the trophoblast shell cells proliferate and form a syncitiotrophoblast and cytotrophoblast layer around he conceptus. Syncitiotrophoblast cells migrate into the uterine wall, forming maternal blood-filled spaces (lacunae).
Placentation begins once the conceptus begins to implant in the uterine wall and the placenta will have both a fetal and a maternal component.
The maternal component is formed by the decidualization of the endometrium.
Maternal Decidua
The maternal uterine endometrium stromal cells (fibroblast-like) are transformed by steroid hormones (progesterone) and embryonic signals into the decidua.
The entire maternal decidua is divided into three regions: decidua basalis, decidua capsularis and decidua parietalis.
These 3 regions are named by their positional relationship to the conceptus.
Decidualization Factors
Activin A
Member of the a transforming growth factor beta (TGFbeta) superfamily, contributes to human endometrial stromal cells (HESC) decidualization and has been localized to decidual cells in the human endometrium. (possibly also BMP2 and TGFbeta1)
Stoikos CJ, Harrison CA, Salamonsen LA, Dimitriadis E. [See Related Articles] A distinct cohort of the TGFbeta superfamily members expressed in human endometrium regulate decidualization. Hum Reprod. 2008 Jun;23(6):1447-56.
References
Reviews
Articles
Search PubMed
Search Pubmed: Maternal Decidua
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Cite this page: Hill, M.A. (2024, April 20) Embryology Placenta - Maternal Decidua. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Placenta_-_Maternal_Decidua
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G