Paper - Development of olfactory and related structures in staged human embryos

Embryology - 18 Apr 2024 Expand to Translate
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Bossy J. Development of olfactory and related structures in staged human embryos. (1980) Anat. Embryol., 161(2);225-36 PMID 7469043

Online Editor

This historic 1980 paper by Bossy described development olfactory and related structures in staged human embryos from the Carnegie Collection.

Modern Notes smell

Historic Embryology - Smell
Historic Embryology: 1902 Olfactory Structures \| 1910 cavum nasi \| 1940 Olfactory and Accessory Olfactory Formations \| 1941 Olfactory nerve \| 1944 Jacobson’s organ \| 1980 Staged embryos

Historic Head Embryology
1910 Skull \| 1910 Skull Images \| 1912 Nasolacrimal Duct \| 1921 Human Brain Vascular \| 1923 Head Subcutaneous Plexus \| 1919 21mm Embryo Skull \| 1920 Human Embryo Head Size \| 1921 43 mm Fetal Skull \| Historic Disclaimer

Historic Embryology - Respiratory
1902 The Nasal Cavities and Olfactory Structures \| 1906 Lung \| 1912 Upper Respiratory Tract \| 1912 Respiratory \| 1913 Prenatal and Neonatal Lung \| 1914 Phrenic Nerve \| 1918 Respiratory images \| 1921 Respiratory \| 1922 Chick Pulmonary Vessels \| 1934 Right Fetal Lung \| 1936 Early Human Lung \| 1937 Terminal Air Passages \| 1938 Human Histology

Search PubMed nasal cavity development

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Pages where the terms "Historic" (textbooks, papers, people, recommendations) appear on this site, and sections within pages where this disclaimer appears, indicate that the content and scientific understanding are specific to the time of publication. This means that while some scientific descriptions are still accurate, the terminology and interpretation of the developmental mechanisms reflect the understanding at the time of original publication and those of the preceding periods, these terms, interpretations and recommendations may not reflect our current scientific understanding. (More? Embryology History \| Historic Embryology Papers)

Summary

The staged sequence of development of the olfactory and related structures has been established from the serially sectioned human embryos of the Carnegie Collection, from stage 11 to stage 23.

The nasal epiblastic thickening appears at stage 11 and the nasal field is well outlined at stage 12. At stage 15, a continuous cellulovascular strand is observed between the nasal groove and the olfactory field. The vomeronasal groove appears at stage 16 (O'Rahilly 1967). During stage 17, the olfactory nerve is organized into two plexuses, lateral and medial, the latter mingled with the terminal-vomeronasal complex. The olfactory bulb begins to appear at stage 18. Stage 19 is characterized by the individualization of the olfactory bulb and nuclei. In addition, the distinction between olfactory structures and terminal and vomeronasal ones begins to be clear. The structure of the olfactory bulb is evident at stage 21. At stage 23, the olfactory strands are well individualized, and olfactory and terminal-vomeronasal fibers are easily distinguishable.

The terminal ganglion is rather terminal-vomeronasal with an autonomic terminal contingent and a sensory one attached to the vomeronasal system.

Carnegie Stages

11 - the nasal epiblastic thickening appears
12 - nasal field is well outlined
15 - a continuous cellulovascular strand is observed between the nasal groove and the olfactory field.
16 - he vomeronasal groove appears.
17 - the olfactory nerve is organized into two plexuses, lateral and medial, the latter mingled with the terminal-vomeronasal complex.
18 - the olfactory bulb begins to appear.
19 - individualization of the olfactory bulb and nuclei. In addition, the distinction between olfactory structures and terminal and vomeronasal ones begins to be clear.
21 - the structure of the olfactory bulb is evident.
23 - the olfactory strands are well individualized, and olfactory and terminal-vomeronasal fibers are easily distinguishable.

**Embryonic Smell Development**
Week FA (GA)	Carnegie Stage	Event
week 4 (GA 6)	11	nasal epiblastic thickening appears
	12	nasal field is well outlined
week 5 (GA 7)	15	continuous cellulovascular strand seen between the nasal groove and the olfactory field
week 6 (GA 8)	16	vomeronasal groove appears.
	17	olfactory nerve is organized into two plexuses, lateral and medial, the latter mingled with the terminal-vomeronasal complex.
week 7 (GA 9)	18	olfactory bulb begins to appear
	19	individualization of the olfactory bulb and nuclei, distinction between olfactory structures and terminal and vomeronasal ones begins to be clear.
week 8 (GA 10)	21	structure of the olfactory bulb is evident.
	23	olfactory strands are well individualized, and olfactory and terminal-vomeronasal fibers are easily distinguishable.
Links: smell \| sensory \| timeline \| Category:Timeline Table Data Reference^[1]

Cite this page: Hill, M.A. (2024, April 18) Embryology Paper - Development of olfactory and related structures in staged human embryos. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Paper_-_Development_of_olfactory_and_related_structures_in_staged_human_embryos

What Links Here?

↑ Bossy J. Development of olfactory and related structures in staged human embryos. (1980) Anat. Embryol., 161(2);225-36 PMID 7469043

[PMID7469043-1] Bossy J. Development of olfactory and related structures in staged human embryos. (1980) Anat. Embryol., 161(2);225-36 PMID 7469043

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