Paper - A list of normal human embryos which have been cut into serial sections: Difference between revisions

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{{Ref-Mall1910}}
{{Ref-Mall1910}}
{| class="wikitable mw-collapsible mw-collapsed"
! Online Editor 
|-
|[[File:Mark_Hill.jpg|50px|left]] This 1910 historic paper by Mall describes the human embryos sectioned in the [[Carnegie Collection]].
<br>
See also {{Mall Links}}
<br>
[[Book - Manual of Human Embryology|Manual of Human Embryology]]
<br><br>
Keibel and Elie received grants from the Grand Duchy of Baden and from the Royal Prussian Academy of Sciences.
* The Grand Duchy of Baden was a state in the southwest German Empire on the east bank of the Rhine that existed between 1806 and 1918.
* The Royal Prussian Academy of Sciences (''Königlich-Preußische Akademie der Wissenschaften'') was an academy established in Berlin, Germany on 11 July 1700.
<br><br>
'''Modern Notes:''' [[Embryonic Development]] | [[Carnegie Collection]] | [[Carnegie Embryos]]


|}
{{Historic Disclaimer}}
{{Historic Disclaimer}}
=A List Of Normal Human Embryos Which Have Been Cut Into Serial Sections=
=A List Of Normal Human Embryos Which Have Been Cut Into Serial Sections=
[[File:Franklin Mall 01.jpg|thumb|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]]
[[Embryology_History_-_Franklin_Mall|Franklin P. Mall]]


Franklin P. Mall
From the Anatomical Laboratory, Johns Hopkins University


From the Anatomical Laboratory, Johns Hopkins University
==Introduction==


At the Baltimore meeting of the Anatomists a number of embryologists requested The Wistar Institute to prepare a catalogue of human embryos found in various laboratories, museums and private collections in the United States, which have been sectioned and mounted for study. Accordingly a blank was prepared which was widely distributed, but replies were obtained from only those laboratories which possessed a number of series of sections. These blanks, which were not uniformly filled out, were given to me by Dr. Greenman, with the request that they be blended into a single list for the use of those interested in human embryology. Before publishing it, Dr. Huber kindly inserted a note in asking for further data, especially concerning specimens which had not yet been reported upon. The replies thus received, together with those secured by Dr. Greenman, make this list as complete as we can hope to make it at the present time.
At the Baltimore meeting of the Anatomists a number of embryologists requested The Wistar Institute to prepare a catalogue of human embryos found in various laboratories, museums and private collections in the United States, which have been sectioned and mounted for study. Accordingly a blank was prepared which was widely distributed, but replies were obtained from only those laboratories which possessed a number of series of sections. These blanks, which were not uniformly filled out, were given to me by Dr. Greenman, with the request that they be blended into a single list for the use of those interested in human embryology. Before publishing it, Dr. Huber kindly inserted a note in asking for further data, especially concerning specimens which had not yet been reported upon. The replies thus received, together with those secured by Dr. Greenman, make this list as complete as we can hope to make it at the present time.
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As the embryos in a collection are usually referred to by the name of the collector, this designation has been retained in this list. By consulting therefore the list of the names of anatomists as given in this volume of it will be easy to learn where an embryo of a given length may be found.
As the embryos in a collection are usually referred to by the name of the collector, this designation has been retained in this list. By consulting therefore the list of the names of anatomists as given in this volume of it will be easy to learn where an embryo of a given length may be found.


The specimens are arranged according to their length. The medium in which they were measured is also given. The number of slides in the series is of value when requests for loans are made. The “remarks” are self explanatory. Only the chief stain is given in each case. Most of the embryos are counterstained; in Minot’s collection often with Lyons blue, in Jackson’s with congo red, in Gage’s with eosin; and in Huber’s and mine, some with eosin and some with congo red.


The specimens are arranged first, according to their crownrump length, then according to the direction of the sections, and finally according to the quality of the series. Only those marked “excellent” or “good” are of great value for study, but in special cases “fair” and “poor” series no doubt will be of value.
The specimens are arranged according to their length. The medium in which they were measured is also given. The number of slides in the series is of value when requests for loans are made. The “remarks” are self explanatory. Only the chief stain is given in each case. Most of the embryos are counterstained; in [[Embryology History - Charles Minot|Minot]]’s [[Harvard Collection|collection]] often with Lyons blue, in Jackson’s with congo red, in Gage’s with eosin; and in [[Embryology History - G. Carl Huber|Huber]]’s and mine, some with eosin and some with congo red.


At a future date it may be desirable to rearrange the specimens with profile outlines of each stage, and this would be a great step in advance, for undoubtedly embryos several millimeters apart in this list may be of the same stage of development. Sooner or later we must designate embryos by their stage of development, not by their crown-rump length,——certainly not by their age, which is the Worst method of all and has brought about much confusion in embryology.


The use of a list as here given is amply justified when we consider the nature of the subject before us. Only by cooperation can we hope to advance the science of human embryology,——a subject which is of first importance to anatomists. Witness the Value of cooperation in His’s “Anatomie menschlisher Embryonen” and in Keibel and Elze’s “Normentafel zur Entwicklungsgeschichte des Menschen.” His secured embryos through the aid of various physicians and scientists, but it took a lifetime for him to make a fairly satisfactory collection of his own, as his various publications will show. Keibel and Elze borrowed embryos from different European collections and thereby were placed at an advantage. These two works are-monumental.
The specimens are arranged first, according to their crownrump length, then according to the direction of the sections, and finally according to the quality of the series. Only those marked “excellent” or “good” are of great value for study, but in special cases “fair” and “poor” series no doubt will be of value.
 
A selected collection of pictures of human embryos which includes several of this list is given in Kollmann’s “Handatlas der Entwicklungsgeschichte des Menschen.” At present there is in preparation a larger work on Human Embryology, in two volumes, which will be published shortly both in Leipzig and Philadelphia. About half of this treatise is being prepared by Americans and is based largely upon the collections represented in this list. This cooperative undertaking is not supported by any research grant, but those who have endowed this work with their energies know only too well that their powers would have been greatly augmented had such support been given. It may here be emphasized that efforts to promote the science of human embryology have not received financial support excepting the work of Keibel and Elze, for which they received grants from the Grand Duchy of Baden and from the Royal Prussian Academy of Sciences.
 
The difficulty of obtaining good material, the care and time consumed in the preparation of good series and in the study of the same (involving often the necessity of making time-consuming reconstructions) makes progress in the study of human embryology very slow. During the past 35 years His repeatedly called attention to the need of financial endowment for, and cooperation in the study of human embryology. At the first meeting of the International Association of Academies, held in Paris in 1901, His proposed that commissions be appointed for the promotion of the study of human embryology and neurology. At that meeting we saw the birth of the Brain Commission, which is working effectively for the study of the brain. A series of Interacadernic Institutes has been established, including our Wistar Institute. At that time the International Association of Academies recommended that the study of human embryology should be supported by various anatomical societies. No steps in this direction were, however, taken by the first International Anatomical Congress, which convened four years later at Geneva. Possibly the Second Congress, which meets this summer in Brussels, may be induced to consider the matter.
 
These statements indicate that anatomists as individuals are cooperating, but their work will progress slowly unless institutes be established to carry it on with greater vigor. is a clear one. Until the human embryo has been thoroughly investigated human anatomy will not rest upon a sound basis.




[[File:Mall1910 table01.jpg|800px]]
At a future date it may be desirable to rearrange the specimens with profile outlines of each stage, and this would be a great step in advance, for undoubtedly embryos several millimeters apart in this list may be of the same stage of development. Sooner or later we must designate embryos by their stage of development, not by their crown-rump length,—certainly not by their age, which is the Worst method of all and has brought about much confusion in embryology.




==Table - Sectioned Embryos==
The use of a list as here given is amply justified when we consider the nature of the subject before us. Only by cooperation can we hope to advance the science of human embryology, — a subject which is of first importance to anatomists. Witness the Value of cooperation in His’s “''Anatomie menschlisher Embryonen''” and in Keibel and Elze’s “''Normentafel zur Entwicklungsgeschichte des Menschen''”. His secured embryos through the aid of various physicians and scientists, but it took a lifetime for him to make a fairly satisfactory collection of his own, as his various publications will show. [[Embryology History - Franz Keibel|Keibel]] and Elze borrowed embryos from different European collections and thereby were placed at an advantage. These two works are -monumental.


{{|
! Collection
! Number of Embryo
! Number of Slides in the Series
! Crown Rump Length of the Embryo in Millimetres
! In what Medium Measured
! Remarks
! Direction of Section
! Thickness of Sections
! Principal Stains
! Condition of the Tissue
|-
| Huber
Mall
Mall
Minot
Minot
Minot
Huber
Mall
Huber
Mall
Mall
Mall
Mall
McMurrich
Mall
Stockard
Mall
Huber
Huber
Mall
McMurrich
McMurrich
Mall
Mall
| 39


134
A selected collection of pictures of human embryos which includes several of this list is given in [[Embryology History - Julius Kollmann|Kollmann]]’s “''Handatlas der Entwicklungsgeschichte des Menschen''”. At present there is in preparation a larger work on [[Book - Manual of Human Embryology|Human Embryology]], in two volumes, which will be published shortly both in Leipzig and Philadelphia. About half of this treatise is being prepared by Americans and is based largely upon the collections represented in this list. This cooperative undertaking is not supported by any research grant, but those who have endowed this work with their energies know only too well that their powers would have been greatly augmented had such support been given. It may here be emphasized that efforts to promote the science of human embryology have not received financial support excepting the work of Keibel and Elze, for which they received grants from the Grand Duchy of Baden and from the Royal Prussian Academy of Sciences.


278


8253
The difficulty of obtaining good material, the care and time consumed in the preparation of good series and in the study of the same (involving often the necessity of making time-consuming reconstructions) makes progress in the study of human embryology very slow. During the past 35 years His repeatedly called attention to the need of financial endowment for, and cooperation in the study of human embryology. At the first meeting of the International Association of Academies, held in Paris in 1901, His proposed that commissions be appointed for the promotion of the study of human embryology and neurology. At that meeting we saw the birth of the Brain Commission, which is working effectively for the study of the brain. A series of Interacadernic Institutes has been established, including our Wistar Institute. At that time the International Association of Academies recommended that the study of human embryology should be supported by various anatomical societies. No steps in this direction were, however, taken by the first International Anatomical Congress, which convened four years later at Geneva. Possibly the Second Congress, which meets this summer in Brussels, may be induced to consider the matter.


1500


1586
These statements indicate that anatomists as individuals are cooperating, but their work will progress slowly unless institutes be established to carry it on with greater vigor. is a clear one. Until the human embryo has been thoroughly investigated human anatomy will not rest upon a sound basis.


43
==Table - Sectioned Embryos==
 
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c=cono1_w_A_1I. _ 1
 
-mxcxnmss or sl-zcnons
m u
 
PRINCIPAL STAIN
H = E EMATOXYLIN
C = CAHMINE
 
CONDITION OF TIBBUI1‘.
E=EXCELLIN'l‘ F'=F'AIH1
(l= GOOD P=PO0R
 
 
 
 
‘ E E
E i  1 E2 '5
5 in «:2 5
COLl.EC'l'!ON ,_ a 5. 5 I 51-: H I E Q
0 i o N_ I a: a I: l T :
2: : zfi :1: 2 . ‘Q: .
'3 53:. ESE  i
E  Ea  go 2 E 2 '
Minot 1129 i 28 ! 13.1 Formalin 3
Mail 338 12  18 Alcohol I
Huber 45 l 69  18.5 Forlnalin 3
Jackson 98 ' 82 ~ 18 Fresh
Greenman 15026 , 69 18.5, Formalin L
Gage 3 ; 86  19 . . . . . . . . .. I
Minot 819 5 32 1 19.0’ Alcohol
Minot 1597 1 .. T 19.3 Formalln
Mall 7 1 9 E 19.5; Alcohol l
Huber 32 40, 19 Formalin l‘
Mall 229 3 22 19 Alcohol ,
Greenman 14597 24 19 Fresh ‘
Mall 293 1 19 19 Formalm
Greenman 15010 1 39 ‘ 19 Formalln
Minot 828 3 39 1 19.0 Alcohol 1
Huber 41  39 ‘ 19 F01-malin
l\Iz1ll 22 1 40 20 Alcohol 1
. 1 ‘ 20 Alcohol 3
Mall 403 ‘ -10 : {23 Formalin I:
Mall 368 ; 34 3 20 . . . . . . . . _. «
Mall 128 37,. 20 Formalln
Mall 24o'o9; 20 | Formalln i
Mall 349 7 20 ' Formalin
M1-Murrich 19  20  20 Formalin j
Minot. 744 ‘g 65 ; 21.0] Alcohol
Minot 852 ' .. 5 21.85 Alcohol
Stockard 1 I163 22 Alcohol !
Collklin 1 . 77 22 ! On slide I
McMu1-rich 1 3 62 22 I Alcohol ‘
Mino‘: 871  59 1 22.3} Alcohol
Kingsbury 27 * 95 T 22
Stockard 6 1208 ‘ 22 Alcohol 3
Minot 851 120‘ 22.0‘ Alcohol ‘
Mall 108 .. 1 22 Slide .
Huber 7 ‘ 80 22 Formalill
 
E : gulf,‘
 
l",,, 13 EE : ,,."““
 
'1:-an i ;. <>< 7 oi‘
 
REMARKS 1:55:11 : Eggl zé
 
-c=->:z= : <<~, 93::
 
£211‘  E11; E12,
 
. . . . . . . .. S E 14 C 2 P
25]
....... .. sland} C I P
L 50J 1
 
. . . . . . . .. C 3 10 H  F
 
. . . . . . . .. C  26 C 1 P
 
. . . . . . . .. C 10 H1‘ F
 
. . . . . . .  T 20 C 3 E
 
. . . . . . .  T 14 C 1 F
 
. . . . . . .  T 12 C ‘, E
 
. . . . . . . ... T 40 C  P
 
. . . . . . .  S 15 H . G
 
. . . . . . . .. s 50 C 1 G
 
. . . . . . . .. C 100 C 1 G
 
. . . . . . . .. s I 50 C { F
 
. . . . . . . .. C 10 H 1 F
 
. . . . . . . .. C 12 C 1 P
 
. . . . . .. C 10 H 1 F
 
. . . . . .. T 50 C ' o
 
. . . . . . . ..  20 H — F
 
. . . . . . . ..i s 20 H 1 P
....... ..l C 50 C I G
. . . . . . . ..i C 20 H G
Inject.ed 1 C 250 None  G
Head ' C 20 II? F
....... .. T I 14 C 1 P
Head s 10 H ! ..
. . . . , . . .. T 10 H; E
. . . . . . . .. T I 6% H | G
. . . . . . . .. T ' 15 C . G
. . . . . . . .. T 1 12 C '1 1-‘
T I 15 C ‘l F
 
. . . . . . . .. s l 10 H G
. . . . . . . .. s 1 12 C ‘ G
. . . . . . . .. s 45 C 3 F
s 15 H ; P
 
 
 
 
364 FRANKLIN P. MALL
 
PRINCIPAL sum
:1 HEMATOXYLIN
 
c CARMINE
 
CONDITION or TISSUE
E=Ex(‘ELLEN"l' 1-‘=rAll:
c=ooon I-=roon
 
O
":5
 
L4
 
oomomooooommmoooozooocmmomooono
ooowwuawqmoww
 
E E E E 9
2- El  c  E
9,: n 3 2 2 3 5,5
5  a 2 a 2 ma 2
COLLECTION E‘ S E E ‘*1  g 3 REMARKS 9 E 2, 2, Z
2 t: E m I: E 2 lg 2 3 E 3 El
2 2 u 5:“ 3 == 5 8 .2 as E i
3 § 5 8 3 E 3? 2 :7 75; 5 '2
2 2 5 E 5 (4 m o F
25 ‘l
Mall 268 34 22 Fornlalin . . . . . . . . . s l and J}
50
Minot 737 00 22.8 Alcohol . . . . . . . . . 7 12
Minot 192 6 23.0 Alcohol Yolk sac T 13
Mall 242 58 23 Alcohol Double T 40
Mall 382 29 23 . . . . . . . . . . Injected S 50
 
Minot 181 68 23.0 Alcohol . . . . . . . . . S 20
 
Gage 9 80 23 . . . . . . . . . . . . . . . . . . . S 20
 
Jackson 147 80 23 Alcohol . . . . . . . . . S 20
 
Stockard 2 206 23 Alcohol . . . . . . . . . ‘ s 10
 
Huber 38 45 23 Alcohol . . . . . . . . . S 15
 
Mall 57 40 23 Alcohol . . . . . . . . . ‘ S 50
 
Jackson 56 117 24 Alcohol . . . . . . . .. T 20
 
Mall 6 38 24 Alcohol . . . . . . . . . T 40
 
Mall 405 31 24 Alcohol . . . . . . . . . S 40
 
. . . . . . . . . ..  26 Formalin  .. ..
Minot 24 29 24.0 Alcohol Head C 20
Minot 38 34 24 . 0 Alcohol Trunk T 20
Mall 10 19 24 Alcohol . . _ _ _ . . . . T 40
 
Mall 314 28 24 Alcohol . . . . . . . . . S 50
 
Kingsbllry 28 88 25.6 . . . . . . . . . . . . . . . . . . . T 15
 
Kingsbury 29 86 25 On slide . . . . . . . . . T 15
 
Huber 33 50 25 Alcohol . . . . . . . . . S 15
 
McMurrich 2 46 26 Alcohol . . . . . . . . . T 20
 
Jackson 99 199 26 Fresh . . . . . . . .. T 20
 
Mall 100 96 27 Alcohol . . . . . . . . . S 50
 
Mall 45 60 28 Alcohol . . . . . . . . . T 50
 
Minot 1598 . . . . 28.8 Formalin . . . . . . . . . S 12
 
Hul)er 49 108 29 Form:l.lin . . . . . . . .. C 15
 
Minot 914 121 29.0 Alcohol . . . . . . . .. C 20
 
Greenman 15024 108 29 Formulin . . . . . . . .. C 15
 
Minot 913 88 30.0 Alcohol . . . . . . . . . T 14
 
Mall 75 105 30 Alcohol . . . . . . . .. S 50
{ 50
 
Mall 227 39 30 . . . . . . . . . . . . . . . . . . . S and
100
 
Huber 15 120 30 Formalin . . . . . . . .. C 20
 
Q Q QQQQQHOWWQWWQWWOQ3
 
 
i E i E E E E 3 § ‘§
la 2 2 5 s 1
E 1 5 N i E a: pa: :3 l 5 E ‘I I" E C
:3] l "5 1:. 2 E g E In p. < >< ‘ 9:. E4
COLLECTION 5‘ ‘iii ‘ En REMARKS ‘°:_,__, 0 15:“: G;
3 2:: “g: 2%‘ %%§§=§ ‘:=E-
  :2 
2 1.=== 3:; 3: 1=E~723l‘:E N51 2“
2 _:“ 5 5 511.115 2:11, 21‘;
Mall 86 115 30 Formalin . . . . . . . .. C ‘ 50 C “ G
Jackson 57 262 31 Fresh . . . . . . . .. T = 20 C f G
Huber 46 169 31 Formalin . . . . . . . .. s 1 15 H E
Gage 11 ‘275 31 . . . . . . . . . . . . . . . . . .. C ‘ 20 H G
.\/Iinot 648 1 25 32.0 Alcohol Head T C F
Minot 649 l 81 32.0 Alcohol Trunk T .. C F
Minot 290 , 42 32.0 Alcohol Head S 20 C F
Minot 292 113 32.0 Alcohol . . . . . . . .. S 24 C F
Minot 291 53 32.0 Alcohol Head C 20 C F
Mall 211 44 33 Formalin . . . . . . . .. S 33 C G
Gage 19 666 34 . . . . . . . . . . . . . . . . . .. T E 15 3 H G
10
Mall 449 103 34 Alcohol Injected S { and? H G
100
Mall 199 64 35 . . . . . . . . .. Incomplete S 50 3 H j G
Huber 22 35 35 Alcohol . . . . . . . .. S 10 H. I F
[ 50 C 1
Jackson 51 46 35 Fornmlin . . . . . . . .. S i and} C F
200
Gage 4 470 36 . . . . . . . . . . . . . . . . . . S 20 H F
Minot 820 264 37.0 Xlcohol . . . . . . . _. T 14 C F
Mall 249 41 37 Alcohol Double T 50 C F
1 f 50
.\I:1ll 145 34 38 Formalin ‘ . . . . . i .. S { and} C G
1 L 100
Huber 17 210 39 Formalin . . . . . . . . 1 C428 10 H E
Jackson 122 100 39 Forrnalin . . . l . . . .. T 60 C F
50
Mall 224 74- 40 Formalin . . . . . . i .. S ll and} C G
100
 
McMurrich 4 46 40 Formalin Head C 40 H G
Minot 838 201 42.0 Alcohol Trunk '1‘ 14 C F
Minot 841 161 42.0 Alcohol Hr.-ad T 14 C F
Minot 1611 .. .. 44.3 Alcohol . . . . . . . . . C&S 14 C G
 
Huber 18 300 45 Form-alin . . . . . . . . C818 10 H E
 
Mall 95 86 46 Formalin . . . . . . . .. S 100 C G
 
Jackson 121 100 46 Formalin . . . . . . . .. I‘ 60 C F
 
Huber 48 189 47 FOTIII‘-Llln . . . . . . . .. S 15 H G
 
01
 
 
0 5 E  w §§
2 §  2 a  ,.
2 3 ,, g E E E 3 E Z  E Z;
co1,m3:m~1ox H -,. E D {:1 E g ‘:3 REMARKS I H _, _: o 3 34 H O H
2 2: “i.:§ afi iii? ;¥. :5; 559
u a: " z :4 *‘ ‘ 5 E 4 " ° z E 3 E0 0
‘£ :5} ggg‘ $5 35% E; 233? gfi
E 2 E E : £1 ll 11 E E :1 ll 8 a <2
Huber 47 48 48 Formalin . . . . . . . . . S 20 H F
 
Mall 84 17 50 Alcohol . . . . . A . . . T 50 C G
 
Gage 10 16 50 . . . . . . . . . . . . . . . . . . . T 15 H G
 
Brodel 3 .. 50 . . . . . . . . .. Injected T .. C G
 
Mall 96 29 50 Formalin . . . . . . . . . S 100 C G
50
 
Mall 184 08 50 Formalin . . . . . . . . . S A ind C G
L 100
 
Jackson 115 37 50 Fresh . . . . . . . . . S 40 C F
 
Gage 15 80 53 . . . . . . . . . . . . . . . . . . . S 15 H G
 
Mall 267 66 59 Formalin Head S 20 Mal- G
 
lor y
 
Huber 23 0‘0 60 Form.-ilin . . . . . . . . . C&T 10 H G
 
Brodel l . 1 60 . . . . T . . . . . Injected T . . . . G
 
Mall 3063 43 60 Formalin Hands S 25 C G
 
Jackson 55 18 65 Formalin Trunk T 50 C F
 
Jackson 55 00 65 Formalin Head T 45 C F
 
l 30l
 
Minot 722 56 78 Alcohol Head T 1 mdj G
37
30
 
Minot 723 58 78 Alcohol Tho: ax T { ind} G
45
 
Minot 724 19 78 Alcohol Abdomen T . . G
 
Minot 725 16 78 Alcohol Abdomen T . . . . G
 
Minot 728 7 78 Alcohol Penis S 15 C G
 
Minot 729 3 78 Alcohol finger S 13 C G
 
Minot 730 6 78 Alcohol Toe S . . C G
 
Mall 44 56 70 Alcohol Trunk T 100 C G
 
Mall 23 59 70 Alcohol Trunk T 100 C G
 
Mall 179 32 70 F ormalin Trunk T 50 C P
30
 
Minot. 720 34 78 Alcohol Face C { ind} G
37
 
Winot 721 19 78 Alcohol Head C 37 . . G
 
Mall 34 60 80 Alcohol Trunk T 50 C G
 
Mall 2345 91 80 Alcohol Head T 50 C G
 
Mall 172 760 80 Alcohol . . . . . . . . . T 100 C G
 
 
 
E E E E E 5
3 a E o 5 gig
: :~ 0 3 I!
I E "‘ H E H z 2 a " r.
s .2 19 H "’
Fri in m 94 2 E E E [L : E Bu E
COLI.EC'l‘10N 8 g E E H E E g namnzxs E 2, i 3 5 3 E :
a: ca 5: a: .. A x— __ ;;
2 SE DEE 5: K-no 22 Egg!) 2'“-7
2 2 2: 5 ME. :5 " E 1: 1 8 H
Huber 25 85 85 Formalin Pelvis S 15 H F
Mall 170 70 80 Alcohol Brain '1‘ 100 C F
Huber 26 70 90 Formalin Pelvis S 15 H G
Huber 20 125 95 Mi'1l1er’s Incomplete S 10 H G
Mall 146 108 95 Formalin Brain T 100 C F
Huber 27 120 95 Alcohol Pelvis S 15 H F
Huber 28 118 100 Formalin Plevis S 15 H G
50
Mall 219 48 115 Fresh Brain S i and C F
[ 100
Brfidel 2 120 . . . . . . . . . . Injected T . . . . G
Mall 120 . . . 125 Alcohol Brain T 100 C F
Mall 48 191 130 Alcohol Abdomen T 100 C G
151
Huber 29 146 135 Formalin Pelvis S { andj H G
20
Huber 30 320 145 Formalin Pelvis S 10 H G
Jackson 54 427 150 Formalin Head C 75 H F
Jackson 54 . . . 150 Formalin Trunk T 100 H F
Mall 220 24 150 Formalin Brain T 100 C P
Huber 31 530 180 Formalin Pelvis S 20 H G
Huber 34 180 180 Formalin Tissues . . . . . . G
l\-'Iin0t 727 5 195 Alcohol Penis T 10 C G
Huber 42 . 240 Formulin Tissues


[[File:Mall1910 table01.jpg|800px]]
[[File:Mall1910 table02.jpg|800px]]
[[File:Mall1910 table03.jpg|800px]]
[[File:Mall1910 table04.jpg|800px]]
[[File:Mall1910 table05.jpg|800px]]
[[File:Mall1910 table06.jpg|800px]]
[[File:Mall1910 table07.jpg|800px]]
[[File:Mall1910 table08.jpg|800px]]
[[File:Mall1910 table09.jpg|800px]]
[[File:Mall1910 table10.jpg|800px]]




{{Footer}}
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[[Category:Historic Embryology]] [[Category:Franklin Mall]]
[[Category:Historic Embryology]] [[Category:Franklin Mall]]
[[Category:Draft]]
[[Category:Draft]][[Category:1910's]][[Category:Carnegie Collection]]

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Mall FP. A list of normal human embryos which have been cut into serial sections. (1910) Anat. Rec. 4(10): 355-367.

Online Editor 
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This 1910 historic paper by Mall describes the human embryos sectioned in the Carnegie Collection.


See also

Franklin Mall Links: Franklin Mall | 1891 26 Day Human Embryo | 1905 Blood-Vessels of the Brain | 1906 Human Ossification | 1910 Manual of Human Embryology 1 | 1912 Manual of Human Embryology 2 | 1911 Mall Human Embryo Collection | 1912 Heart Development | 1915 Tubal Pregnancy | 1916 Human Magma in Normal and Pathological Development | 1917 Frequency Human Abnormalities | 1917 Human Embryo Cyclopia | 1918 Embryo Age | 1918 Appreciation | 1934 Franklin Mall biography PDF | Mall photograph | Mall painting | Mall painting | Carnegie Stages | Carnegie Embryos | Carnegie Collection | Category:Franklin Mall


Manual of Human Embryology

Keibel and Elie received grants from the Grand Duchy of Baden and from the Royal Prussian Academy of Sciences.

  • The Grand Duchy of Baden was a state in the southwest German Empire on the east bank of the Rhine that existed between 1806 and 1918.
  • The Royal Prussian Academy of Sciences (Königlich-Preußische Akademie der Wissenschaften) was an academy established in Berlin, Germany on 11 July 1700.



Modern Notes: Embryonic Development | Carnegie Collection | Carnegie Embryos

Historic Disclaimer - information about historic embryology pages 
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Pages where the terms "Historic" (textbooks, papers, people, recommendations) appear on this site, and sections within pages where this disclaimer appears, indicate that the content and scientific understanding are specific to the time of publication. This means that while some scientific descriptions are still accurate, the terminology and interpretation of the developmental mechanisms reflect the understanding at the time of original publication and those of the preceding periods, these terms, interpretations and recommendations may not reflect our current scientific understanding.     (More? Embryology History | Historic Embryology Papers)

A List Of Normal Human Embryos Which Have Been Cut Into Serial Sections

Franklin Mall (1911)

Franklin P. Mall

From the Anatomical Laboratory, Johns Hopkins University

Introduction

At the Baltimore meeting of the Anatomists a number of embryologists requested The Wistar Institute to prepare a catalogue of human embryos found in various laboratories, museums and private collections in the United States, which have been sectioned and mounted for study. Accordingly a blank was prepared which was widely distributed, but replies were obtained from only those laboratories which possessed a number of series of sections. These blanks, which were not uniformly filled out, were given to me by Dr. Greenman, with the request that they be blended into a single list for the use of those interested in human embryology. Before publishing it, Dr. Huber kindly inserted a note in asking for further data, especially concerning specimens which had not yet been reported upon. The replies thus received, together with those secured by Dr. Greenman, make this list as complete as we can hope to make it at the present time.

There are about 300 specimens listed in this catalogue, and of these about one-half are well preserved. When it is considered that the series of human embryos in the embryological collection of the Anatomical Laboratory of Johns Hopkins University are selected from about 1000 abortions, it may safely be stated that but 5 per cent of them yield good serial sections of normal embryos. This list then is a selected one from about 3000 abortions, ‘ova, embryos and young foetuses.


As the embryos in a collection are usually referred to by the name of the collector, this designation has been retained in this list. By consulting therefore the list of the names of anatomists as given in this volume of it will be easy to learn where an embryo of a given length may be found.


The specimens are arranged according to their length. The medium in which they were measured is also given. The number of slides in the series is of value when requests for loans are made. The “remarks” are self explanatory. Only the chief stain is given in each case. Most of the embryos are counterstained; in Minot’s collection often with Lyons blue, in Jackson’s with congo red, in Gage’s with eosin; and in Huber’s and mine, some with eosin and some with congo red.


The specimens are arranged first, according to their crownrump length, then according to the direction of the sections, and finally according to the quality of the series. Only those marked “excellent” or “good” are of great value for study, but in special cases “fair” and “poor” series no doubt will be of value.


At a future date it may be desirable to rearrange the specimens with profile outlines of each stage, and this would be a great step in advance, for undoubtedly embryos several millimeters apart in this list may be of the same stage of development. Sooner or later we must designate embryos by their stage of development, not by their crown-rump length,—certainly not by their age, which is the Worst method of all and has brought about much confusion in embryology.


The use of a list as here given is amply justified when we consider the nature of the subject before us. Only by cooperation can we hope to advance the science of human embryology, — a subject which is of first importance to anatomists. Witness the Value of cooperation in His’s “Anatomie menschlisher Embryonen” and in Keibel and Elze’s “Normentafel zur Entwicklungsgeschichte des Menschen”. His secured embryos through the aid of various physicians and scientists, but it took a lifetime for him to make a fairly satisfactory collection of his own, as his various publications will show. Keibel and Elze borrowed embryos from different European collections and thereby were placed at an advantage. These two works are -monumental.


A selected collection of pictures of human embryos which includes several of this list is given in Kollmann’s “Handatlas der Entwicklungsgeschichte des Menschen”. At present there is in preparation a larger work on Human Embryology, in two volumes, which will be published shortly both in Leipzig and Philadelphia. About half of this treatise is being prepared by Americans and is based largely upon the collections represented in this list. This cooperative undertaking is not supported by any research grant, but those who have endowed this work with their energies know only too well that their powers would have been greatly augmented had such support been given. It may here be emphasized that efforts to promote the science of human embryology have not received financial support excepting the work of Keibel and Elze, for which they received grants from the Grand Duchy of Baden and from the Royal Prussian Academy of Sciences.


The difficulty of obtaining good material, the care and time consumed in the preparation of good series and in the study of the same (involving often the necessity of making time-consuming reconstructions) makes progress in the study of human embryology very slow. During the past 35 years His repeatedly called attention to the need of financial endowment for, and cooperation in the study of human embryology. At the first meeting of the International Association of Academies, held in Paris in 1901, His proposed that commissions be appointed for the promotion of the study of human embryology and neurology. At that meeting we saw the birth of the Brain Commission, which is working effectively for the study of the brain. A series of Interacadernic Institutes has been established, including our Wistar Institute. At that time the International Association of Academies recommended that the study of human embryology should be supported by various anatomical societies. No steps in this direction were, however, taken by the first International Anatomical Congress, which convened four years later at Geneva. Possibly the Second Congress, which meets this summer in Brussels, may be induced to consider the matter.


These statements indicate that anatomists as individuals are cooperating, but their work will progress slowly unless institutes be established to carry it on with greater vigor. is a clear one. Until the human embryo has been thoroughly investigated human anatomy will not rest upon a sound basis.

Table - Sectioned Embryos

Mall1910 table01.jpg Mall1910 table02.jpg Mall1910 table03.jpg Mall1910 table04.jpg Mall1910 table05.jpg Mall1910 table06.jpg Mall1910 table07.jpg Mall1910 table08.jpg Mall1910 table09.jpg Mall1910 table10.jpg



Cite this page: Hill, M.A. (2024, April 19) Embryology Paper - A list of normal human embryos which have been cut into serial sections. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Paper_-_A_list_of_normal_human_embryos_which_have_been_cut_into_serial_sections

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