Neural System - Molecular: Difference between revisions
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===Spinal Cord=== | ===Spinal Cord=== | ||
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| Model of the embryonic rostro-caudal gradient of neurogenesis along the chicken spinal cord from the stem zone to the neurogenic neural tube summarising how DELTA-NOTCH signalling may be involved in these processes. | | Model of the embryonic rostro-caudal gradient of neurogenesis along the chicken spinal cord from the stem zone to the neurogenic neural tube summarising how DELTA-NOTCH signalling may be involved in these processes.{{#pmid:18000541|PMID18000541}} | ||
* Caudal to rostral decreasing FGF gradient, leads to Delta-1 expression decrease in cells that leave the stem zone (light blue) and move into the PNTZ where they intermingle with cells that do not express Delta-1. | * Caudal to rostral decreasing FGF gradient, leads to Delta-1 expression decrease in cells that leave the stem zone (light blue) and move into the PNTZ where they intermingle with cells that do not express Delta-1. | ||
* Generates differences in DELTA/NOTCH signalling between adjacent cells that may initiate lateral inhibition. | * Generates differences in DELTA/NOTCH signalling between adjacent cells that may initiate lateral inhibition. | ||
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[[File:Hypothalamus gene interaction model.jpg|600px]] | [[File:Hypothalamus gene interaction model.jpg|600px]] | ||
Hypothalamus Development Gene Interaction Model | Hypothalamus Development Gene Interaction Model{{#pmid:24360028|PMID24360028}} | ||
:'''Links:''' [[Endocrine_-_Hypothalamus_Development|Hypothalamus Development]] | :'''Links:''' [[Endocrine_-_Hypothalamus_Development|Hypothalamus Development]] | ||
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===Reviews=== | ===Reviews=== | ||
===Search Pubmed=== | ===Search Pubmed=== |
Revision as of 12:18, 21 March 2018
Embryology - 25 Apr 2024 Expand to Translate |
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Introduction
Draft Page - notice removed when complete.
Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
- Molecular System Links: Heart | Neural | Renal | Respiratory | Mechanisms | Factors | Molecular
Some Recent Findings
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More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Notch <pubmed limit=5>Notch</pubmed> |
Notch
Spinal Cord
Model of the embryonic rostro-caudal gradient of neurogenesis along the chicken spinal cord from the stem zone to the neurogenic neural tube summarising how DELTA-NOTCH signalling may be involved in these processes.[1]
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Hypothalamus
Hypothalamus Development Gene Interaction Model[2]
- Links: Hypothalamus Development
References
- ↑ Hämmerle B & Tejedor FJ. (2007). A novel function of DELTA-NOTCH signalling mediates the transition from proliferation to neurogenesis in neural progenitor cells. PLoS ONE , 2, e1169. PMID: 18000541 DOI.
- ↑ Ratié L, Ware M, Barloy-Hubler F, Romé H, Gicquel I, Dubourg C, David V & Dupé V. (2013). Novel genes upregulated when NOTCH signalling is disrupted during hypothalamic development. Neural Dev , 8, 25. PMID: 24360028 DOI.
Reviews
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External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- OMIM - NOTCH 1
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Cite this page: Hill, M.A. (2024, April 25) Embryology Neural System - Molecular. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_System_-_Molecular
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G