Neural System - Glial Development

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Introduction

Within the neural tube stem cells generate the 2 major classes of cells that make the majority of the nervous system: neurons and glia. Both these classes of cells differentiate into many different types generated with highly specialized functions and shapes. This section covers the establishment of glial populations, the inductive influences of surrounding tissues and the sequential generation of neurons establishing the layered structure seen in the brain and spinal cord.

Glial cells have many different roles in neural development, though they are typically described as "supportive", and have the same early embryonic origins as neurons.

Types of glia: radial glia, astroglia, oligodendroglia, microglia and Schwann cells.

Development the neural crest and sensory systems (hearing/vision/smell) are only briefly introduced in these notes and are covered in detail in another notes sections. (More? Neural Crest Notes Senses Notes)


Neural Links: ectoderm | neural | neural crest | ventricular | sensory | Stage 22 | gliogenesis | neural fetal | Medicine Lecture - Neural | Lecture - Ectoderm | Lecture - Neural Crest | Lab - Early Neural | neural abnormalities | folic acid | iodine deficiency | Fetal Alcohol Syndrome | neural postnatal | neural examination | Histology | Historic Neural | Category:Neural

| Neural Crest Development | Sensory System Development | original Neural page


Some Recent Findings

  • Neural Stem Cell Differentiation[1] "Upon evaluating distinct growth-permissive substrates in an embryonic stem cell‚Äìneurogenesis assay, we found that laminin, fibronectin, and gelatin instruct neural fate and alter the functional specification of neurons when applied at distinct stages of development." (More? Stem Cells )
  1. <pubmed>16832065</pubmed>PNAS