Neural Crest Development: Difference between revisions
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== Some Recent Findings == | == Some Recent Findings == | ||
* Derivation of neural crest cells from human pluripotent stem cells. Lee G, Chambers SM, Tomishima MJ, Studer L. Nat Protoc. 2010 Apr;5(4):688-701. Epub 2010 Mar 18. [http://www.ncbi.nlm.nih.gov/pubmed/20360764 PMID: 20360764] | |||
== Textbooks == | == Textbooks == | ||
Revision as of 09:50, 14 April 2010
Introduction
The neural crest are bilaterally paired strips of cells arising in the ectoderm at the margins of the neural tube. These cells migrate to many different locations and differentiate into many cell types within the embryo. This means that many different systems (neural, skin, teeth, head, face, heart, adrenal glands, gastrointestinal tract) will also have a contribution fron the neural crest cells.
In the body region, neural crest cells also contribute the peripheral nervous system (both neurons and glia) consisting of sensory ganglia (dorsal root ganglia), sympathetic and parasympathetic ganglia and neural plexuses within specific tissues/organs.
In the head region, neural crest cells migrate into the pharyngeal arches (as shown in movie below) forming ectomesenchyme contributing tissues which in the body region are typically derived from mesoderm (cartilage, bone, and connective tissue).
General neural development is also covered in Neural Notes.
--Mark Hill 09:25, 14 April 2010 (EST) Page Template only - content from original UNSW Embryology site currently being edited and updated.
Links: Category:Neural Crest | original Neural Crest Development page
Some Recent Findings
- Derivation of neural crest cells from human pluripotent stem cells. Lee G, Chambers SM, Tomishima MJ, Studer L. Nat Protoc. 2010 Apr;5(4):688-701. Epub 2010 Mar 18. PMID: 20360764
Textbooks
Objectives
- Understand the structures derived from ectoderm.
- Understand the formation of neural folds.
- Identify the initial location of neural crest cells in the trilaminar embryo.
- Identify pathways of neural crest migration throughout the embryo.
- To know the major tissues to which neural crest cells contribute.
- To know how abnormalities in development that result from abnormal neural crest cell migration.
- Understand how neural crest cells contribute to the pharyngeal arches and the head structures they form.
Computer Activities
Development Overview
References
Reviews
Articles
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Cite this page: Hill, M.A. (2024, April 18) Embryology Neural Crest Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_Crest_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
