Neural Crest - Schwann Cell Development: Difference between revisions
No edit summary |
|||
| Line 20: | Line 20: | ||
<pubmed></pubmed> | <pubmed></pubmed> | ||
===Search PubMed=== | ===Search PubMed=== | ||
'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=] | '''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Cell%20Development Schwann Cell Development] | ||
==External Links== | ==External Links== | ||
{{Template:External Links}} | {{Template:External Links}} | ||
Revision as of 16:59, 8 December 2010
Introduction
Some Recent Findings
| * Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin[1]"Current opinion holds that pigment cells, melanocytes, are derived from neural crest cells produced at the dorsal neural tube and that migrate under the epidermis to populate all parts of the skin. Here, we identify growing nerves projecting throughout the body as a stem/progenitor niche containing Schwann cell precursors (SCPs) from which large numbers of skin melanocytes originate. SCPs arise as a result of lack of neuronal specification by Hmx1 homeobox gene function in the neural crest ventral migratory pathway. Schwann cell and melanocyte development share signaling molecules with both the glial and melanocyte cell fates intimately linked to nerve contact and regulated in an opposing manner by Neuregulin and soluble signals including insulin-like growth factor and platelet-derived growth factor. These results reveal SCPs as a cellular origin of melanocytes, and have broad implications on the molecular mechanisms regulating skin pigmentation during development, in health and pigmentation disorders." |
Table colours
dark blue bgcolor="DDCEF2" light blue bgcolor="F5FAFF"
References
- ↑ <pubmed>19837037</pubmed>
Reviews
<pubmed></pubmed>
Articles
<pubmed></pubmed>
Search PubMed
Search Pubmed: Schwann Cell Development
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 24) Embryology Neural Crest - Schwann Cell Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_Crest_-_Schwann_Cell_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
