Neural Crest - Cardiac

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Introduction

Cardiac Neural Crest Migration
Cardiac Neural Crest Migration

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Cardiac neural crest has an important contribution to the developing heart outflow tract.[1] It has been shown to not contribute to any of the heart conduction system.[2]

Neural Crest Links: neural crest | Lecture - Early Neural | Lecture - Neural Crest Development | Lecture Movie | Schwann cell | adrenal | melanocyte | peripheral nervous system | enteric nervous system | cornea | cranial nerve neural crest | head | skull | cardiac neural crest | Nicole Le Douarin | Neural Crest Movies | neural crest abnormalities | Category:Neural Crest
Student Projects 2023: 1 Patterning neural border and NC | 2 NPB NEUcrest | 3 EMT and NC | 4 miRNA and NC | 5 Adrenal Gland and NC | 6 Melanocyte & Melanoma | 7 Neurocristopathies | Neural Crest
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Historic Embryology - Neural Crest  
1879 Olfactory Organ | 1905 Cranial and Spinal Nerves | 1908 10 mm Peripheral | 1910 Mammal Sympathetic | 1920 Human Sympathetic | 1928 Cranial ganglia | 1939 10 Somite Embryo | 1942 Origin | 1957 Adrenal

Cardiovascular System Development

Some Recent Findings

  • FGF8 signaling is chemotactic for cardiac neural crest cells[3] "neural crest cells migrate into the pharyngeal arches where they support development of the pharyngeal arch arteries. The pharyngeal endoderm and ectoderm both express high levels of FGF8. We hypothesized that FGF8 is chemotactic for cardiac crest cells. To begin testing this hypothesis, cardiac crest was explanted for migration assays under various conditions. Cardiac neural crest cells migrated more in response to FGF8."
More recent papers  
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Search term: Cardiac Neural Crest

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Cardiac Neural Crest

<pubmed limit=5>Cardiac Neural Crest</pubmed>


References

  1. Creazzo TL, Godt RE, Leatherbury L, Conway SJ & Kirby ML. (1998). Role of cardiac neural crest cells in cardiovascular development. Annu. Rev. Physiol. , 60, 267-86. PMID: 9558464 DOI.
  2. Boullin J & Morgan JM. (2005). The development of cardiac rhythm. Heart , 91, 874-5. PMID: 15958352 DOI.
  3. Rosa AL, Alvarez ME, Lawson D & Maccioni HJ. (1990). A polypeptide of 59 kDa is associated with bundles of cytoplasmic filaments in Neurospora crassa. Biochem. J. , 268, 649-55. PMID: 2141976

Reviews

Plein A, Fantin A & Ruhrberg C. (2015). Neural crest cells in cardiovascular development. Curr. Top. Dev. Biol. , 111, 183-200. PMID: 25662261 DOI.

Keyte AL, Alonzo-Johnsen M & Hutson MR. (2014). Evolutionary and developmental origins of the cardiac neural crest: building a divided outflow tract. Birth Defects Res. C Embryo Today , 102, 309-23. PMID: 25227322 DOI.

Creazzo TL, Godt RE, Leatherbury L, Conway SJ & Kirby ML. (1998). Role of cardiac neural crest cells in cardiovascular development. Annu. Rev. Physiol. , 60, 267-86. PMID: 9558464 DOI.

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Cite this page: Hill, M.A. (2024, April 19) Embryology Neural Crest - Cardiac. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_Crest_-_Cardiac

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G