Molecular Development - microRNA: Difference between revisions

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==Functional miRNA Grouping==
==Functional miRNA Grouping==
The following identifies microRNAs that have been identified with specific developmental processes, based upon a commercial collation of basic research data.


===Pluripotency===
===Pluripotency===
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Data: SABiosciences [http://www.sabiosciences.com/mirna_pcr_product/HTML/MIHS-103Z.html Cell Differentiation & Development miRNA PCR Array]
Data: SABiosciences [http://www.sabiosciences.com/mirna_pcr_product/HTML/MIHS-103Z.html Cell Differentiation & Development miRNA PCR Array]


==References==
==References==

Revision as of 19:38, 28 November 2011

Introduction

Micro RNA (miRNA) are 22 nucleotide non-coding RNAs. These small pieces of RNA have been identified as important negative regulators in both development and adult cell processes involving gene expression.


Molecular Links: molecular | genetics | epigenetics | mitosis | meiosis | X Inactivation | Signaling | Factors | Mouse Knockout | microRNA | Mechanisms | Developmental Enhancers | Protein | Genetic Abnormal | Category:Molecular

Some Recent Findings

Chromosome structure

[1]

Links: References | More References


Functional miRNA Grouping

The following identifies microRNAs that have been identified with specific developmental processes, based upon a commercial collation of basic research data.

Pluripotency

  • let-7a, let-7b, let-7c, let-7d, let-7e, let-7g, miR-101, miR-106b, miR-125b, miR-130a, miR-133b, miR-141, miR-15a, miR-17, miR-182, miR-183, miR-18a, miR-18b, miR-205, miR-20a, miR-20b, miR-21, miR-214, miR-22, miR-222, miR-23b, miR-24, miR-302a, miR-302c, miR-345, miR-424, miR-498, miR-518b, miR-520g.

Early Development

  • Embryoid Bodies: miR-132, miR-181a, miR-9.
  • Definitive Endoderm: miR-205, miR-375.

Ectoderm

  • Neurological Development: let-7b, miR-103a, miR-106b, miR-10b, miR-124, miR-125b, miR-130a, miR-132, miR-134, miR-137, miR-16, miR-181a, miR-182, miR-183, miR-20a, miR-210, miR-219-5p, miR-22, miR-23b, miR-24, miR-26a, miR-302a, miR-302c, miR-7, miR-9, miR-96.
  • Eye Development: miR-130a, miR-196a, miR-219-5p, miR-23b, miR-96.
  • Epidermal Differentiation: let-7b, miR-205, miR-210, miR-23b, miR-26a.
  • Inner Ear Development: miR-182, miR-183, miR-96.

Mesoderm

  • Hematopoiesis: let-7e, miR-125a-5p, miR-142-3p, miR-223.
  • T Cell Development: let-7a, let-7f, miR-106b, miR-142-5p, miR-146b-5p, miR-150, miR-15a, miR-15b, miR-16, miR-181a, miR-20a, miR-222, miR-26a.
  • Erythropoiesis: let-7a, let-7b, let-7c, let-7d, let-7f, let-7g, let-7i, miR-126, miR-128a, miR-137, miR-155, miR-15b, miR-16, miR-17, miR-181a, miR-182, miR-185, miR-206, miR-21, miR-22, miR-222, miR-24, miR-26a, miR-96.
  • Lymphopoiesis: let-7b, miR-125b, miR-128a, miR-16, miR-181a, miR-21, miR-24.
  • Megakaryopoiesis: miR-106b, miR-10a, miR-10b, miR-122, miR-126, miR-127-5p, miR-129-5p, miR-134, miR-146a, miR-150, miR-155, miR-17, miR-18a, miR-192, miR-20a, miR-20b, miR-21, miR-22, miR-301a, miR-33a, miR-378, miR-92a, miR-93.
  • Monocyte Differentiation: miR-155, miR-222, miR-424.
  • Myelopoiesis: miR-103a, miR-128a, miR-17, miR-181a, miR-24.
  • Angiogenesis: miR-126, miR-130a, miR-218, miR-222, miR-92a.
  • Myogenesis: miR-1, miR-125b, miR-206, miR-26a.
  • Osteogenesis: miR-141, miR-15b, miR-424.
  • Adipogenesis: let-7b, let-7c, let-7e, miR-100, miR-101, miR-103a, miR-10b, miR-146b-5p, miR-155, miR-182, miR-192, miR-194, miR-196a, miR-21, miR-210, miR-214, miR-22, miR-24, miR-498, miR-96, miR-99a.
  • Chondrogenesis: let-7f, miR-1, miR-132, miR-181a, miR-196a, miR-96, miR-99a.
  • Heart Development: miR-1, miR-208, miR-488.

Endoderm

  • Liver Development: let-7a, let-7b, let-7c, miR-10a, miR-122, miR-125b, miR-192, miR-21, miR-22, miR-23b, miR-92a, miR-99a.
  • Pancreatic Development: miR-15a, miR-15b, miR-16, miR-195, miR-214, miR-375, miR-7, miR-9.
  • Intestinal Development: let-7d, let-7e, miR-103a, miR-106b, miR-125b, miR-126, miR-130a, miR-141, miR-146b-5p, miR-17, miR-192, miR-194, miR-21, miR-215, miR-301a, miR-424.


Data: SABiosciences Cell Differentiation & Development miRNA PCR Array

References

  1. <pubmed></pubmed>

Reviews

<pubmed></pubmed>

Articles

<pubmed>18029362</pubmed>| Nucleic Acids Res. <pubmed></pubmed> <pubmed></pubmed>


Search Pubmed

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Cite this page: Hill, M.A. (2024, March 28) Embryology Molecular Development - microRNA. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Molecular_Development_-_microRNA

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