Integumentary System - Gland Development
Introduction
The secretory glands associated with the integumentary system have similar embryonic origins and mechanisms of development, though are specialised by their locations and secretions. A key process and feature of all gland development is an epithelial-mesenchymal interaction(s). Gland secretion can also be regulated by a number of different mechanisms, including endocrine changes postnatally at puberty and during pregnancy.
The mammary gland development is covered in detail on a separate notes page.
Some Recent Findings
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Textbooks
- Human Embryology (2nd ed.) Larson Chapter 14 p443-455
- The Developing Human: Clinically Oriented Embryology (6th ed.) Moore and Persaud Chapter 20: P513-529
- Before We Are Born (5th ed.) Moore and Persaud Chapter 21: P481-496
- Essentials of Human Embryology Larson Chapter 14: P303-315
- Human Embryology, Fitzgerald and Fitzgerald
- Color Atlas of Clinical Embryology Moore Persaud and Shiota Chapter 15: p231-236
Development of Glands
- 2 main types - sweat and sebaceous
- both ectodermal in origin
- form as ingrowth of ectoderm into the mesoderm
Sweat Gland
- mostly eccrine some apocrine
- apocrine in axilla, pubic and nipple regions
- see also mammary gland development
Sebaceous Gland
- associated with hair development
- except plans penis and labia minora
- these glands secrete vernix
Vernix Caseosa
(vernix, Latin, vernix = varnish, caseous = cheese=like] term describing a coating formed on the fetal skin surface by: secreted sebum, cells sloughed off the fetus's skin, and shed lanugo hair.
The coating also has a high water content (80%) largely compartmentalized within fetal corneocytes (cells forming the stratum corneum).
This coating develops intially in a cranio-caudal direction and can be absent in preterm infants.
Some functions include:
- protection of the fetal skin from extraembryonic fluids amnion, urine
- providing a slippery surface helps with parturition (birth)
- acting as a biofilm barrier against infection
Abnormalities
References
- ↑ <pubmed>20382343</pubmed>
Journals
Reviews
<pubmed>20565255</pubmed> <pubmed>20484386</pubmed> <pubmed>19889198</pubmed> <pubmed>19020961</pubmed>
Articles
<pubmed>20689821</pubmed> <pubmed>20584313</pubmed> <pubmed>20552032</pubmed>| PLoS One.
Search PubMed
Search Pubmed: Epithelial Gland Development | Sweat Gland Development | Sebaceous Gland Development | Eccrine Gland Development | Apocrine Gland Development
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Cite this page: Hill, M.A. (2024, March 28) Embryology Integumentary System - Gland Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Integumentary_System_-_Gland_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G