Integumentary System - Abnormalities

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Introduction

This page introduces abnormalities associated with the integumentary system and its specializations. Note that each related page will also contain specific information for that component of this system.

Integumentary Links: integumentary | Lecture | hair | tooth | nail | integumentary gland | mammary gland | vernix caseosa | melanocyte | touch | Eyelid | outer ear | Histology | integumentary abnormalities | Category:Integumentary
Hair Links  
Hair Links: Overview | Lanugo | Neonatal | Vellus | Terminal | Hair Follicle | Follicle Phases | Stem Cells | Molecular | Pattern | Puberty | Histology | Hair Colour | Arrector Pili Muscle | Hair Loss | Integumentary
Touch Links  
Touch Links: Touch Receptors | Touch Pathway | Pacinian Corpuscle | Meissner's Corpuscle | Merkel Cell | Sensory Modalities | Neural Crest Development | Neural System Development | Student project | Integumentary | Sensory System
Historic Embryology - Integumentary  
1906 Papillary ridges | 1910 Manual of Human Embryology | 1914 Integumentary | 1923 Head Subcutaneous Plexus | 1921 Text-Book of Embryology | 1924 Developmental Anatomy | 1941 Skin Sensory | Historic Disclaimer
Tinycc  
http://tiny.cc/Integument_Development

Some Recent Findings

  • Comparison between human fetal and adult skinCite error: Closing </ref> missing for <ref> tag

The BreastScreen Australia monitoring report 2011-2012 presents the latest national statistics on this national screening program, which aims to reduce illness and death resulting from breast cancer through organised screening to detect cases of unsuspected breast cancer in women, thus enabling early intervention.

  • Around 55% of women in the target age group of 50-69 took part in the program, with more than 1.7 million women screening in 2011-2012.
  • Breast cancer mortality is at an historic low, at 44 deaths per 100,000 women.


Vascular Abnormalities

Angiomas are vascular disorder resulting in excessive skin vascularisation.

OMIM Database Search: "Angioma" (2005 - 23 search results)

Skin Colour Abnormalities

There are many different factors that can affect skin colouration, some are genetically related while others are due to diet or pharmacological drug side effects.

Albinism autosomal recessive trait resulting in lack of pigment in skin, hair and retina.

Jaundice is the yellow color of skin (and mucous membranes) and is not an abnormality of the skin and is often seen in newborn infants. It is due to accumulation of bile pigments in blood and their deposition in body tissues.

Carotenemia excess carotene intake results from eating large quantities of green and yellow vegetables, tomatoes, or yellow corn.

Quinacrine used for treatment of giardiasis, produces a yellow skin color, but the urine remains normal.

OMIM Database Search: "albinism" (2005 - 73 search results) | "Jaundice" (2005 - 121 search results)

Melanoma

Melanocytes (neural crest) normally protect the postnatal skin cells against UV damage. Melanoma develops when melanocytes become malignantly transformed, these cells can then become invasive and spread to other tissues.

There are several different forms:

  • Superficial spreading melanoma - most common type of melanoma about 70% of all melanomas.
  • Nodular melanoma - about 15% of all melanomas and becomes invasive soon after first appearing.
  • Acral-lentiginous melanoma - about 8% of all melanomas and is the most common melanoma in dark-skinned people.
  • Lentigo maligna melanoma - about 5% of melanomas.
  • Amelanotic melanoma - rare and has an absence of pigmentation.
  • Desmoplastic melanoma - rare about 1.7% of all melanomas.


Links: [SEER Training Module

References


Reviews

Articles

Search Pubmed

Search Pubmed: Integumentary System Development

Ehlers-Danlos Syndrome


Abnormality Links: abnormal development | abnormal genetic | abnormal environmental | Unknown | teratogens | ectopic pregnancy | cardiovascular abnormalities | coelom abnormalities | endocrine abnormalities | gastrointestinal abnormalities | genital abnormalities | head abnormalities | integumentary abnormalities | musculoskeletal abnormalities | limb abnormalities | neural abnormalities | neural crest abnormalities | placenta abnormalities | renal abnormalities | respiratory abnormalities | hearing abnormalities | vision abnormalities | twinning | Developmental Origins of Health and Disease |  ICD-11
Historic Embryology  
1915 Congenital Cardiac Disease | 1917 Frequency of Anomalies in Human Embryos | 1920 Hydatiform Degeneration Tubal Pregnancy | 1921 Anencephalic Embryo | 1921 Rat and Man | 1966 Congenital Malformations


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Cite this page: Hill, M.A. (2024, April 25) Embryology Integumentary System - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Integumentary_System_-_Abnormalities

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G