Immune System - Abnormalities

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Introduction

Lymphatic vessel development cartoon
Lymphatic vessel development[1]


Developing Human Thymus (Carnegie stage 22)
Developing Human Thymus (stage 22)


Immune Links: immune | blood | spleen | thymus | Lymphatic | lymph node | Antibody | Med Lecture - Lymphatic Structure | Med Practical | Immune Movies | vaccination | bacterial infection | Abnormalities | Category:Immune
Historic Embryology  
1909 Lymph glands | 1912 Development of the Lymphatic System | 1918 Gray's Lymphatic Images | 1916 Pig Lymphatics | 1919 Chicken Lymphatic | 1921 Spleen | 1922 Pig Stomach Lymphatics | 1932 Cat Pharyngeal Tonsil | Historic Disclaimer

Some Recent Findings

  • Tie1 is required for lymphatic valve and collecting vessel development[2] "Tie1 is a receptor tyrosine kinase with broad expression in embryonic endothelium. Reduction of Tie1 levels in mouse embryos with a hypomorphic Tie1 allele resulted in abnormal lymphatic patterning and architecture, decreased lymphatic draining efficiency, and ultimately, embryonic demise. ... Our findings reveal a fundamental role for Tie signaling during lymphatic vessel remodeling and valve morphogenesis and implicate it as a candidate gene involved in primary lymphedema."
More recent papers
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Search term: Immune System Abnormalities

<pubmed limit=5>Immune System Abnormalities</pubmed>


Cite this page: Hill, M.A. (2019, October 23) Embryology Immune System - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Immune_System_-_Abnormalities

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
  1. <pubmed>19138383</pubmed>| PMC2646268 | Genome Biology
  2. <pubmed>25576926</pubmed>