Histology Artifacts: Difference between revisions

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Embryology - 18 Apr 2024 Expand to Translate
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Introduction

There are many steps in the preparation and processing of tissue sections that can introduce artefacts into the original tissue. This page introduces some of the steps in tissue preparation where this can occur and the type of artefact that appears in the final tissue. The pages on histology fixatives and stains should be read in conjunction with this page.

In histology, if it looks interesting, it is probably an artefact!

Draft page - Notice removed when completed.

Historic Histology Textbooks: 1941 Histology] | 1944 Oral Histology

Histology Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | ANAT2241 Support | Histology | Histology Stains | Embryology Glossary

Artifacts

Prefixation artifacts
Fixation artifacts
Artifacts related to bone tissue
Tissue-processing artifacts
Artifacts related to microtomy
Artifacts related to floatation and mounting
Staining artifacts
Mounting artifacts

Prefixation Artifacts

Anything that may have been done to the tissue before it has been preserved by fixation. This includes handling, physical distortion, drug treatments or injections, tissue degeneration, or poor tissue preparation for fixation.

Fixation Artifacts

Fixative solution osmolality

Hypertonic can cause cellular shrinkage and increased extracellular spaces.
Hypotonic can cause cell swelling.

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link

Cite this page: Hill, M.A. (2024, April 18) Embryology Histology Artifacts. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Histology_Artifacts

What Links Here?

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 {{Header}}
 == Introduction==
-There are many steps in the preparation and processing of tissue sections that can introduce artefacts into the original tissue. This page introduces some of the steps in tissue preparation where this can occur and the type of artefact that appears in the final tissue.
+There are many steps in the preparation and processing of tissue sections that can introduce artefacts into the original tissue. This page introduces some of the steps in tissue preparation where this can occur and the type of artefact that appears in the final tissue. The pages on histology {{fixatives}} and {{stains}} should be read in conjunction with this page.
+<br><br>
 <center>''In histology, if it looks interesting, it is probably an artefact!''</center>
+<br><br>
+Draft page - Notice removed when completed.
+<br>
 {{Histology Links}}
+==Artifacts==
 * Prefixation artifacts
 * Fixation artifacts
@@ Line 18: / Line 19: @@
 * Mounting artifacts
+==Prefixation Artifacts==
+Anything that may have been done to the tissue before it has been preserved by fixation. This includes handling, physical distortion, drug treatments or injections, tissue degeneration, or poor tissue preparation for fixation.
+==Fixation Artifacts==
+Fixative solution osmolality
+* Hypertonic can cause cellular shrinkage and increased extracellular spaces.
+* Hypotonic can cause cell swelling.