Genital - Male Development
Introduction
The male and female reproductive systems develop initially "indifferently", it is the product of the Y chromosome SRY gene that makes the "difference". The mesonephric duct (Wolffian Duct) contributes the majority of male internal genital tract.
Embryonic gonad development leads to the mesonephric/paramesonephric duct changes, while the external genitaila remain indeterminate in appearance through to the fetal period.
Importantly its sex chromosome dependence, late embryonic/fetal differential development, complex morphogenic changes, long time-course, hormonal sensitivity and hormonal influences make it a system prone to many different abnormalities.
There are also currently separate pages describing Spermatozoa Development | Testis Development | Prostate Development.
| Puberty
Some Recent Findings
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Textbooks
- Human Embryology (2nd ed.) Larson Chapter 10 p261-306
- The Developing Human: Clinically Oriented Embryology (6th ed.) Moore and Persaud Chapter 13 p303-346
- Before We Are Born (5th ed.) Moore and Persaud Chapter 14 p289-326
- Essentials of Human Embryology, Larson Chapter 10 p173-205
- Human Embryology, Fitzgerald and Fitzgerald Chapter 21-22 p134-152
- Developmental Biology (6th ed.) Gilbert Chapter 14 Intermediate Mesoderm
Movies
Genital development animations
Urogenital Sinus | Urogenital Septum |
Male External | Testis Descent |
Primordial germ cell migration (mouse)
Migration 1 | Migration 2 | Migration 3 |
Development Overview
Three main stages during development, mesonephric/paramesonephric duct changes are one of the first male/female differences that occur in development, while external genitaila remain indeterminate in appearance for quite a while.
- Differentiation of gonad (Sex determination)
- Differentiation of internal genital organs
- Differentiation of external genital organs
The 2nd and 3rd stages dependent on endocrine gonad. Reproductive development has a long maturation timecourse, begining in the embryo and finishing in puberty. (More? Puberty Development)
Historic Images of Genital Changes
Urogenital indifferent | Urogenital male | Urogenital female |
Additional Images
Stages of primordial germ cell migration[4]
References
- ↑ <pubmed>20674196</pubmed>
- ↑ <pubmed>19906863</pubmed>
- ↑ <pubmed>19159697</pubmed>
- ↑ <pubmed> 20027186</pubmed>| Nature Reviews Molecular Cell Biology
Reviews
Articles
Search PubMed
Search Pubmed: Male Genital System Development | mesonephric duct
Terms
Glossary Links
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Cite this page: Hill, M.A. (2024, April 19) Embryology Genital - Male Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Genital_-_Male_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G