Gastrointestinal Tract - Liver Development: Difference between revisions
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{{Template:Gastrointestinal Tract Links}} | [http://embryology.med.unsw.edu.au/Notes/git7.htm original page] | {{Template:Gastrointestinal Tract Links}} | [http://embryology.med.unsw.edu.au/Notes/git7.htm original page] | ||
== Liver Development Stages == | |||
{| class="prettytable" | |||
| <center>'''Carnegie Stage'''</center> | |||
| '''Feature''' | |||
|- | |||
| <center>11</center> | |||
| hepatic diverticulum development | |||
|- | |||
| <center>12</center> | |||
| '''cell differentiation''' | |||
septum transversum forming liver stroma | |||
hepatic diverticulum forming hepatic trabeculae | |||
|- | |||
| <center>13</center> | |||
| epithelial cord proliferation enmeshing stromal capillaries | |||
|- | |||
| <center>14</center> | |||
| hepatic gland and its vascular channels enlarge | |||
hematopoietic function appeared | |||
|- | |||
| <center>18</center> | |||
| obturation due to epithelial proliferation | |||
bile ducts became reorganized (continuity between liver cells and gut) | |||
|- | |||
| <center>18 to 23</center> | |||
| biliary ductules developed in periportal connective tissue | |||
produces ductal plates that receive biliary capillaries | |||
<div align="right">(More? [../week/weekbyweekdetail.htm Development Week by Week - Detailed])</div> | |||
|} | |||
Data from Godlewski G, etal.<ref><pubmed>9407542</pubmed></ref> "Stage 11 was characterized by hepatic diverticulum development, stage 12 and thereafter by cellular differentiation (septum transversum giving the liver stroma and hepatic diverticulum the hepatic trabeculae), and stage 13 by epithelial cord proliferation enmeshing stromal capillaries. From stage 14, the hepatic gland and its vascular channels presented considerable enlargement while hematopoietic function appeared. From this stage, the development of cystic primordium, never present in rat, was constant in man. At stage 18, after a period of obturation due to epithelial proliferation, the bile ducts became reorganized and ensured the continuity between liver cells and gut. From stages 18 to 23, biliary ductules developed in periportal connective tissue producing ductal plates that received biliary capillaries." | |||
See also Liver development in the rat during the embryonic period (Carnegie stages 15-23).<ref><pubmed>9718390</pubmed></ref> | |||
==References== | ==References== |
Revision as of 14:27, 22 August 2010
Introduction
This section of notes gives an overview of how the liver develops. The transverse septum (septum transversum) arises at an embryonic junctional site. The junctional region externally is where the ectoderm of the amnion meets the endoderm of the yolk sac. The junctional region internally is where the foregut meets the midgut. The mesenchymal structure of the transverse septum provides a support within which both blood vessels and the liver begin to form. This structure grows rapidly.
Liver Development Stages
Feature | |
hepatic diverticulum development | |
cell differentiation
septum transversum forming liver stroma hepatic diverticulum forming hepatic trabeculae | |
epithelial cord proliferation enmeshing stromal capillaries | |
hepatic gland and its vascular channels enlarge
hematopoietic function appeared | |
obturation due to epithelial proliferation
bile ducts became reorganized (continuity between liver cells and gut) | |
biliary ductules developed in periportal connective tissue
produces ductal plates that receive biliary capillaries (More? [../week/weekbyweekdetail.htm Development Week by Week - Detailed])
|
Data from Godlewski G, etal.[1] "Stage 11 was characterized by hepatic diverticulum development, stage 12 and thereafter by cellular differentiation (septum transversum giving the liver stroma and hepatic diverticulum the hepatic trabeculae), and stage 13 by epithelial cord proliferation enmeshing stromal capillaries. From stage 14, the hepatic gland and its vascular channels presented considerable enlargement while hematopoietic function appeared. From this stage, the development of cystic primordium, never present in rat, was constant in man. At stage 18, after a period of obturation due to epithelial proliferation, the bile ducts became reorganized and ensured the continuity between liver cells and gut. From stages 18 to 23, biliary ductules developed in periportal connective tissue producing ductal plates that received biliary capillaries."
See also Liver development in the rat during the embryonic period (Carnegie stages 15-23).[2]
References
Reviews
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20169088
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Cite this page: Hill, M.A. (2024, March 29) Embryology Gastrointestinal Tract - Liver Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Gastrointestinal_Tract_-_Liver_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G