File:Thermoreceptor development diagram.JPG

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Revision as of 10:51, 3 October 2012 by Z3331951 (talk | contribs) (This diagram shows some of the genes required for the development of the thermosensory nerves. Under the influence of Neurog1 and Neurog2, nerve progenitors begin to express TrkA, a nerve growth factor receptor. Approximately 50% of these nerves continue )
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This diagram shows some of the genes required for the development of the thermosensory nerves. Under the influence of Neurog1 and Neurog2, nerve progenitors begin to express TrkA, a nerve growth factor receptor. Approximately 50% of these nerves continue to express TrkA during differentiation, the other half however start expressing RET, a glial-cell-derived neurotrophic factor. This differentiation occurs under the influence of Runx1, a transcription factor. It is from the pool of RET+ neurons that nerves expressing the thermoTRP ion channels develop. These nerves are capable of thermosensation.

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current10:51, 3 October 2012Thumbnail for version as of 10:51, 3 October 2012576 × 635 (29 KB)Z3331951 (talk | contribs)This diagram shows some of the genes required for the development of the thermosensory nerves. Under the influence of Neurog1 and Neurog2, nerve progenitors begin to express TrkA, a nerve growth factor receptor. Approximately 50% of these nerves continue
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