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=Reelin signalling in cerebellum development=
=Reelin signalling in cerebellum development=
 
Reelin is a large glycoprotein that acts on the receptors VLDLR and ApoER2 which in turn acts on Dab1 adapter protein to induce downstream cellular changes.  Reelin functions in releasing purkinje cells from radial glia after migration and formation of the monolayer of purkinje cells.<ref><Pubmed>PMC1800349</Pubmed></ref>
==Summary==
Reelin is a large glycoprotein that acts on the receptors VLDLR and ApoER2 which in turn acts on Dab1 adapter protein to induce downstream cellular changes.  Reelin functions in releasing purkinje cells from radial glia after migration and formation of the monolayer of purkinje cells.<ref>Zhang, G., Assadi, A. H., McNeil, R. S., Beffert, U., Wynshaw-Boris, A., Herz, J., . . . D'Arcangelo, G. (2007). The Pafah1b Complex Interacts with the Reelin Receptor VLDLR. PLoS ONE, 2(2), 252nd ser. doi:https://doi.org/10.1371/journal.pone.0000252</ref>


==Reference==
==Reference==
<references/>
<references/>


==Link==
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800349/
==Copyright==
==Copyright==
Copyright Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Copyright Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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Latest revision as of 17:49, 25 October 2017

Reelin signalling in cerebellum development

Reelin is a large glycoprotein that acts on the receptors VLDLR and ApoER2 which in turn acts on Dab1 adapter protein to induce downstream cellular changes. Reelin functions in releasing purkinje cells from radial glia after migration and formation of the monolayer of purkinje cells.[1]

Reference

  1. <Pubmed>PMC1800349</Pubmed>

Copyright

Copyright Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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current18:59, 22 October 2017Thumbnail for version as of 18:59, 22 October 2017478 × 547 (37 KB)Z5177699 (talk | contribs)Reelin is a large glycoprotein that acts on the receptors VLDLR and ApoER2 which in turn acts on Dab1 adapter protein to induce downstream cellular changes.

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