Latest revision as of 14:28, 22 October 2015

Diagram of pronuclear transfer

Create an zygote using the parents’ sperm and eggs .
At the same time, a second Zygote is created using a donor egg with healthy mitochondria and the father’s (or donor) sperm.
The pronuclei are removed from the single-cell stage embryo (day one). The leftover enucleated embryo with diseased mitochondria is discarded.
The pronuclei of the second embryo are removed and discarded.
The parents’ pronuclei can be placed into the second embryo for development.
The developed embryo will then be transferred into the mother.

Reference

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@@ Line 2: / Line 2: @@
 *Create an zygote using the parents’ sperm and eggs .
-*At the same time, a second embryo is created using a donor egg with healthy mitochondria and the father’s (or donor) sperm.
+*At the same time, a second Zygote is created using a donor egg with healthy mitochondria and the father’s (or donor) sperm.
 *The pronuclei are removed from the single-cell stage embryo (day one). The leftover enucleated embryo with diseased mitochondria is discarded.
 *The pronuclei of the second embryo are removed and discarded.