File:Pax and DNA interaction.jpg

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Pax and DNA interaction

All PAX proteins contain a transactivation domain and a DNA-binding domain known as the paired domain (PD). The PD consists of PAI and RED subdomains, each of which is composed of three helices in a helix-turn-helix motif. Some PAX family members also contain an additional DNA-binding homeodomain and/or an octapeptide region.


Links: Developmental Signals - Pax

Reference

<pubmed>24496612</pubmed>| Development

Copyright

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Figure 1 http://dev.biologists.org/content/141/4/737/F1.expansion.html Panel A cropped from figure 1, resized and relabelled. Text above modified from figure legend.

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current11:10, 8 July 2014Thumbnail for version as of 11:10, 8 July 2014700 × 927 (93 KB)Z8600021 (talk | contribs)==Pax and DNA interaction== All PAX proteins contain a transactivation domain and a DNA-binding domain known as the paired domain (PD). The PD consists of PAI and RED subdomains, each of which is composed of three helices in a helix-turn-helix motif....

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