File:Normal control muscle (a) vs. Duchennes muscular dystrophy muscle (b).jpg

Immunofluorescence with anti-AQP4 antibody of normal control muscle (a) and Duchenne muscular dystrophy muscle (DMD) (b), and that with anti-spectrin antibody of serial muscle section of DMD (c). Positive immunoreactivity with anti-AQP4 antibody is seen in apparently all myofibers of normal control muscles (a); while it is noted in mosaic pattern in DMD muscle (b). DMD muscle contains less numerous myofibers with positive immunoreactivity of anti-AQP4 antibody (b) than myofibers with that of anti-spectrin antibody (c). Scattered anti-AQP4 immunonegative fibers (asterisks in (b)) are noted in DMD muscle. Scale bar in (a)–(c) = 50μm.

Normal control muscle (a) vs. Duchennes muscular dystrophy muscle (b).jpg

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Assessment

+ Good to show actual immunofluorescence of protein localisation. - No citation included image information as required by file criteria, this is a major error. - Clumsy file naming is a minor eror.

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Cite this page: Hill, M.A. (2024, April 20) Embryology Normal control muscle (a) vs. Duchennes muscular dystrophy muscle (b).jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Normal_control_muscle_(a)_vs._Duchennes_muscular_dystrophy_muscle_(b).jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G