Difference between revisions of "File:Ngn1 and Ngn2 in DRG development.png"

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===Copyright within Journal Article===
 
===Copyright within Journal Article===
Note: These panels(A-J) were cropped from the original image.
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Note: These panels (A-L) were cropped from the original image.
  
 
©2011 Hu et al; licensee BioMed Central Ltd.
 
©2011 Hu et al; licensee BioMed Central Ltd.

Revision as of 14:27, 16 October 2018

Normal expression of neurogenins in Rbpj-deficient DRG. (A-L) Transverse sections through the upper neural tube (nt) and surrounding tissue of wild-type (WT) and Rbpj CKO with Ngn1 (A-F) and Ngn2 (G-L) mRNA probes at the indicated stages. Loss of Rbpj does not appear to affect the expression of neurogenins either in migrating NCCs at E9.5 and E10.0, or in post-migratory NCCs in the DRG at E10.0 and E10.5. Arrows in (A,B,G,H) point to a cluster of migrating NCCs, and those in (C-F,I-L) point to post-migratory NCCs condensed in the DRG located laterally to the neural tube. High magnification views of the areas delineated by black rectangles in panels (C-F,I,J) are shown at the bottom of each panel. Note that the signal of in situ hybridization is present in the cytoplasm, whereas the nuclei contain no signals.

Reference

Hu, Z.-L., Shi, M., Huang, Y., Zheng, M.-H., Pei, Z., Chen, J.-Y., … Ding, Y.-Q. (2011). The role of the transcription factor Rbpj in the development of dorsal root ganglia. Neural Development, 6, 14. http://doi.org/10.1186/1749-8104-6-14

Copyright

Copyright within Journal Article

Note: These panels (A-L) were cropped from the original image.

©2011 Hu et al; licensee BioMed Central Ltd.

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current00:47, 15 October 2018Thumbnail for version as of 00:47, 15 October 2018384 × 557 (212 KB)Z5229597 (talk | contribs)This figure compares of the concentration of cells expressing Ngn-1 and Ngn-2 in the DRG between wild-type and Rbpj knock out mice at E10.0 and E10.5. This figure demonstrates that loss of Rbpj function does not affect neurogenin activity either in the...

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