File:Neutrophil 01.jpg: Difference between revisions
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==Neutrophil== | ==Neutrophil== | ||
* neutrophil granulocyte or polymorphonuclear leukocyte (PMN). | |||
* most common leukocyte in blood smears, about 60% neutrophils (50% - 70%) | |||
* nucleus is divided into 3-5 lobes connected by thin strands of chromatin. | |||
* lobe number increases with cell age (old cells up to 7 lobes). | |||
* contain two types of granules stain only weakly if they are at all visible ("neutral"). | |||
{| | |||
| | |||
===Granules=== | |||
* primary granules (A granules) | |||
** contain lysosomal enzymes and are probably primary lysosomes. | |||
** larger (0.4 µm) than the typical primary lysosome. | |||
* secondary granules (B granules) | |||
** the specific granules of the neutrophils | |||
** contain enzymes with strong bactericidal actions | |||
** these granules stain only weakly if they are at all visible ("neutral"). | |||
| | |||
===Functions=== | |||
* neutrophils locate and eliminate pathogens (bacterial and fungal) and regulate immunity and inflammation. | |||
* ability to release neutrophil extracellular traps. | |||
* Newly identified roles PMID 23825232 | |||
** proposed to participate in protection against intracellular pathogens (viruses and mycobacteria). | |||
** involved in adaptive immune response. | |||
** mediate alternative pathway of systemic anaphylaxis | |||
** participate in allergic skin reactions. | |||
** improper activation may also lead to tissue damage during an autoimmune or exaggerated inflammatory reaction | |||
|} | |||
{{Neutrophil model links}} | |||
{{Blood Histology}} | {{Blood Histology}} | ||
{{Blue Histology}} | |||
[[Category:Blood]] [[Category:Histology]] | [[Category:Blood]] [[Category:Histology]] |
Latest revision as of 09:04, 6 March 2015
Neutrophil
- neutrophil granulocyte or polymorphonuclear leukocyte (PMN).
- most common leukocyte in blood smears, about 60% neutrophils (50% - 70%)
- nucleus is divided into 3-5 lobes connected by thin strands of chromatin.
- lobe number increases with cell age (old cells up to 7 lobes).
- contain two types of granules stain only weakly if they are at all visible ("neutral").
Granules
|
Functions
|
- Immune Links: Neutrophil classical model | Neutrophil novel model | image - neutrophil histology | Immune System Development
- Blood Histology: Blood Development | Blood Cell Number Table | Lymphocyte 1 | Lymphocyte 2 | Lymphocyte 3 | Lymphocyte 4 | Monocyte 1 | Monocyte 2 | Monocyte 3 | Monocyte 4 | Neutrophils 1 | Neutrophil 2 | Neutrophil 3 | Neutrophil 4 | Eosinophil 1 | Eosinophil 2 | labeled Neutrophil and Eosinophil | unlabeled - Neutrophil and Eosinophil | Basophil 1 | Basophil 2 | Basophil 3 | Platelet 1 | Platelet 2 | Reticulocyte | Megakaryocyte | Movie | Bone Marrow Histology | Category:Blood
Blood Cells |
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Adult human blood cell numbers shown in the table below is for reference purposes.
Blood Cell NumbersThe adult ranges of cells / 1 litre (l), total blood volume is about 4.7 to 5 litres. Blood Development | Blood Histology Red Blood Cells
Leukocytes (white blood cells)
Granulocytes
Non-Granulocytes
Lymphocytes
Platelets
|
Links: Histology | Histology Stains | Blue Histology images copyright Lutz Slomianka 1998-2009. The literary and artistic works on the original Blue Histology website may be reproduced, adapted, published and distributed for non-commercial purposes. See also the page Histology Stains.
Cite this page: Hill, M.A. (2024, April 25) Embryology Neutrophil 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Neutrophil_01.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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