File:Neural-development.jpg

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Timeline of Events in Human Neural Development

This simplified overview graph shows broad events of neural development classified by proliferation, migration, differentiation and metabolism.

Note the long time course of neural development and that this process continues postnatally. This long timeline means that the nervous system has one of the longest critical periods of development, and the events shown above can be affected by specific teratogens either before or during their window of development.


  • 19 weeks (GA 21 weeks) - at the end of neuronal migration, radial glial cells transformation into astrocytes and astrocytic precursors. PMID: 3339373


Timeline Links: human timeline | mouse timeline | mouse detailed timeline | chicken timeline | rat timeline | zebrafish timeline | Medaka | comparative | Category:Timeline
Human Trimesters - Systems  
Period: first trimester timeline | second trimester timeline | third trimester timeline

Systems: bone timeline | eye neural crest timeline | heart abnormality timeline | hearing timeline | hearing EAM timeline | muscle timeline | ovary timeline | pelvis timeline | placental villi timeline | shoulder timeline | smell timeline | spleen timeline | ventricular timeline

Historic  
upper limb ossification timeline | lower limb ossification timeline | 1932 Guinea pig day 11-21 | 1933 Guinea pig day 21-35
Embryology History: 1600-1699 | 1700-1799 | 1800-1899 | 1900-1909 | 1910-1919 | 1920-1929 | 1930-1939 | 1940-1949 | 1950-1959 | 1960-1969 | 1970-1979 | 1980-1989 | 1990-1999 | Historic Papers | Embryologists


  Critical Period Links: critical period | abnormal development | Critical Periods table | Image - Critical Periods table | Genital | Opioids | Neural | Thalidomide | Environmental


Neural Links: ectoderm | neural | neural crest | ventricular | sensory | Stage 22 | gliogenesis | neural fetal | Medicine Lecture - Neural | Lecture - Ectoderm | Lecture - Neural Crest | Lab - Early Neural | neural abnormalities | folic acid | iodine deficiency | Fetal Alcohol Syndrome | Postnatal | Postnatal - Neural Examination | Histology | Historic Neural | Category:Neural

Reference

Evrard P. Gadisseux J.-F. and Gressens P. Hypoxia Opportunism During Brain Development. (1993) from: Report of the Workshop on Acute Perinatal Asphyxia in Term Infants, U.S. Department of Health and Human Services, Public Health Service, NIH, National Institute of Child Health and Human Development. August 30-31, 1993.

Original File name: https://www.nichd.nih.gov/publications/pubs/acute/PublishingImages/p44_5.gif

Kadhim HJ, Gadisseux JF & Evrard P. (1988). Topographical and cytological evolution of the glial phase during prenatal development of the human brain: histochemical and electron microscopic study. J. Neuropathol. Exp. Neurol. , 47, 166-88. PMID: 3339373

Ge WP, Miyawaki A, Gage FH, Jan YN & Jan LY. (2012). Local generation of glia is a major astrocyte source in postnatal cortex. Nature , 484, 376-80. PMID: 22456708 DOI.


Cite this page: Hill, M.A. (2019, October 20) Embryology Neural-development.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Neural-development.jpg

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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