File:Nephron development 02.jpg

From Embryology

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Stages in nephron development. Nephron development. (A) In mammals, the kidney develops from the metanephric mesenchyme upon invasion of the ureteric bud out of the nephric duct. (B and C) The ureteric bud starts branching within the growing metanephric mesenchyme. (D) The mesenchyme condenses around the ureteric bud tips forming the Six2-positive cap mesenchyme. (E) Renal vesicles form from the condensed cap mesenchyme. (F) A cleft develops in the comma-shaped bodies. (G) Podocyte progenitors start to attract angioblasts in the s-shaped body. (H) The developing nephron connects with the collecting duct. [1]


  1. C. Schell, et al. Glomerular development – Shaping the multi-cellular filtration unit. Retrieved September 18, 2017, from


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